The Jonathan Coleman Lab
Research
Our lab is focused on understanding the mechanism of disease recurrence, response to therapies and disease progression of upper tract urothelial cancer, a rare but aggressive disease. To interrogate molecular diversity of the disease, we employ genomics, transcriptomics, metabolomics and tumor immune microenvironment profiling of patient samples as well as patient derived organoids and xenograft models generated in our lab.
Our laboratory has also been developing novel photodynamic therapies for local tumor ablation. The preclinical models are used in support of translational studies for ongoing clinical trials across multiple cancer types. Combination studies of photoablation with immunotherapies are an active area of investigation
People
Jonathan Coleman, MD
- Jonathan Coleman is a physician-scientist focused on translational research, cancer genomics, and patient-derived organoid models in the study of urologic malignancies. Ongoing work includes the development of local ablative therapies, their influence on the tumor microenvironment, and implications for therapy response.
- MD, Cornell University Medical College
- [email protected]
- Email Address
- 646-422-4432
- Office Phone
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