The Karlo Perica Lab

The laboratory of Dr. Karlo Perica focuses on developing new Chimeric Antigen Receptor T cell and other cell therapies for cancer. We seek to make cell therapy more accessible and more effective by developing “off-the-shelf” approaches using allogeneic cell therapies and in vivo editing.

Our research spans the scientific spectrum from basic studies in animal models, to translational and correlative work with patient samples, to development of new cell therapy products. Ongoing projects include developing allogeneic cells that resist immune rejection, gene editing of CAR T cells to enhance potency and function, translational research on the correlates of CAR T cell response in patients, and in vivo gene editing of T cells.

Research Projects

• Projects