Developmental Biology Program

The Anna-Katerina Hadjantonakis Lab

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Pictured: Anna-Katerina Hadjantonakis
Anna-Katerina Hadjantonakis, PhD
Chair, Developmental Biology Program, SKI

Cancer is a condition promoted by cells undergoing an identity crisis. An understanding of how cells control their identity (cell fate specification), and how they organize themselves into normal tissues (morphogenesis) provides the blueprint for the fundamental biological processes that become deregulated in cancer. 

The Hadjantonakis laboratory uses high-resolution quantitative methods to investigate the mechanisms underlying stem cell specification, cellular differentiation, tissue organization and growth. They use the mammalian embryo as a platform, and the mouse as a primary model system. They also exploit in vitro cultured stem cells, including pluripotent stem cells, for their studies. 

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Research Projects

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Inside My Lab: Anna-Katerina Hadjantonakis

Go inside the lab of Anna-Katerina Hadjantonakis from SKI’s Developmental Biology Program.
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The Anna-Katerina Hadjantonakis Lab

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Kat Hadjantonakis
At Work: Developmental Biologist Anna-Katerina Hadjantonakis

In the Lab
In this fluorescent microscopy image of endoderm tissue from a mouse embryo, cell membranes are red, cell nuclei are blue, and extra-embryonic endoderm cells are green (they appear turquoise because blue and green are merged).
Scientists Rewrite the Textbook of Organ Development, One Cell at a Time

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Five scientists in a lab
Out of the Closet, into the Lab: Five LGBTQ Scientists Share Their Stories

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Publications

Saiz N, Mora-Bitria L, Rahman S, George H, Herder J, Garcia-Ojalvo J, Hadjantonakis AK.  Growth factor-mediated coupling between lineage size and cell fate choice underlies robustness of mammalian development. Elife. 2020 Jul 28;9:e56079. doi: 10.7554/eLife.56079.

Nowotschin S, Setty M, Kuo YY, Liu V, Garg V, Sharma R, Simon CS, Saiz N, Gardner R, Boutet SC, Church DM, Hoodless PA, Hadjantonakis AK, Pe’er D. The emergent landscape of the mouse gut endoderm at single-cell resolution. Nature. 2019 May;569(7756):361-367. doi: 10.1038/s41586-019-1127-1.

Morgani SM, Metzger JJ, Nichols J, Siggia ED, Hadjantonakis AK. Micropattern differentiation of mouse pluripotent stem cells recapitulates embryo regionalized cell fate patterning. Elife. 2018 Feb 7;7. pii: e32839. doi: 10.7554/eLife.32839.

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People

Pictured: Anna-Katerina Hadjantonakis

Anna-Katerina Hadjantonakis, PhD

Chair, Developmental Biology Program, SKI

  • The Hadjantonakis laboratory studies pluripotency, cell lineage commitment, tissue patterning, and morphogenesis in mammalian embryos and in vitro stem cell models.
  • PhD, Imperial College (London)
hadjanta@mskcc.org
Email Address
212-639-3159
Office Phone

Members

Kat Hadjantonakis, PhD
Kat Hadjantonakis

Member

Abderhman Abuhashem
Abderhman Abuhashem

Graduate Student

Evan Bardot

Postdoctoral Research Fellow

Nicole Clerico
Nicole Clerico

Administrative Assistant

Vidur Garg
Vidur Garg

Graduate Student

Ying-Yi Kuo
Ying-Yi Kuo

Senior Research Technician

Sophie Morgani, PhD
Sophie Morgani

Research Fellow - joint with Dr. Jenny Nichols at Cambridge University

Sonja Nowotschin, PhD
Sonja Nowotschin

Senior Research Scientist

Jonathan Pai
Jonathan Pai

Graduate Student

Clayton Schwarz
Clayton Schwarz

Research Fellow – joint with Dr. Eric Siggia at Rockefeller University

Claire Simon

Research Fellow - NYSTEM Training Award at the CSCB

Lab Alumni
Jerome Artus

Postdoctoral Research Fellow

Sophie Balmer
Sophie Balmer

Postdoctoral Research Fellow

John Burrowes

Administrative Assistant

Lydia Coleman
Lydia Coleman

Administrative Assistant

Anna Ferrer-Vaquer

Research Fellow

Laina Freyer
Laina Freyer

Postdoctoral Research Fellow

Benjamin Gordon
Benjamin Gordon

Research Technician

Minjung Kang, BS
Minjung Kang

Graduate Student

Xinghua Lou

Research Fellow

Silvia Munoz-Descalzo

Visiting Research Fellow

Ricky Narvaez
Ricky Narvaez

Research Technician

Yvonne Pao

Research Technician

Anna Piliszek

Postdoctoral Research Fellow

Berenika Plusa

Visiting Research Fellow

Maria Pulina

Postdoctoral Research Fellow

Nestor Saiz Arenales, PhD
Nestor Saiz Arenales

Postdoctoral Research Fellow

Kristy Schmicking

Administrative Assistant II

Nadine Schrode
Nadine Schrode

Graduate Research Assistant

Rowena Turnbull

Research Technician

Manuel Viotti

Graduate Student

Evan Weiner

Research Technician

Tao Wu, PhD
Tao Wu

Postdoctoral Research Fellow

Panos Xenopoulos

Postdoctoral Research Fellow

Lab Affilations

Open Positions

Postdoctoral Fellow Position

Individuals in the final stages of their graduate studies who are interested in working on mechanisms driving pluripotency transitions, lineage differentiation and the morphogenesis of nascent organs in mammalian models, and/or the construction of stem cell-derived mammalian embryo-like structures, are always encouraged to apply for Postdoctoral Fellow positions in the lab.

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Disclosures

Doctors and faculty members often work with pharmaceutical, device, biotechnology, and life sciences companies, and other organizations outside of MSK, to find safe and effective cancer treatments, to improve patient care, and to educate the health care community.

MSK requires doctors and faculty members to report (“disclose”) the relationships and financial interests they have with external entities. As a commitment to transparency with our community, we make that information available to the public.

Anna-Katerina Hadjantonakis discloses the following relationships and financial interests:

No disclosures meeting criteria for time period


The information published here is for a specific annual disclosure period. There may be differences between information on this and other public sites as a result of different reporting periods and/or the various ways relationships and financial interests are categorized by organizations that publish such data.

This page and data include information for a specific MSK annual disclosure period (January 1, 2019 through disclosure submission in spring 2020). This data reflects interests that may or may not still exist. This data is updated annually.

Learn more about MSK’s COI policies here. For questions regarding MSK’s COI-related policies and procedures, email MSK’s Compliance Office at ecoi@mskcc.org.


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