Inside My Lab: Scott Lowe
About the Scott Lowe Lab
Our laboratory studies tumor-suppressor networks controlling apoptosis and senescence and how their disruption influences malignant behavior.
Scott Lowe Lab Plasmid and Animal Requests
Request plasmids through addgene More »
For plasmids not listed on addgene, please contact the lab manager, Anne Trumble-Koncelik, trumblea@mskcc.org.
For animal requests, please contact the mouse colony manager, Janelle Simon, simonj@mskcc.org.
Scott W. Lowe, PhD
Chair, Cancer Biology & Genetics Program, SKI; Chair, Geoffrey Beene Cancer Research Center
Professor
Research Focus
Cancer biologist Scott Lowe uses genetically engineered mouse models to study how the genetic alterations in cancer cells contribute to tumorigenesis, alter treatment response, and create molecular vulnerabilities that may be targeted therapeutically.Education
PhD, Massachusetts Institute of Technology- Office Phone: 646-888-3342
- Office Fax: 646-888-3347
- Lab Phone 646-888-3340
- Lab Phone 646-888-3345
- Lab Fax: 646-888-3347
Lab Members
Corina Amor Vegas
Graduate Student
Direna Alonso Curbelo
Postdoctoral Researcher
Francisco Barriga
Postdoctoral Researcher
Hsuan-An Chen
Graduate Student
Yu-Jui (Ray) Ho
Computational Biologist
Shauna Houlihan
Postdoctoral Researcher
Josef Leibold
Postdoctoral Researcher
Grace Xiang Li
Graduate Student
Evangelia Loizou
Graduate Student
Riccardo Mezzadra
Postdoctoral Researcher
John P. Morris IV
Postdoctoral Researcher
Scott Millman
Postdoctoral Researcher
Stella V. Paffenholz
Graduate Student
Jose Reyes
Postdoctoral Researcher
Marcus Ruscetti
Postdoctoral Researcher
Francisco Sanchez-Rivera
Postdoctoral Researcher
Kaloyan Tsanov
Postdoctoral Researcher
Charles J. Sherr
Visiting Investigator/Advisor
Lynn Boss
Administrative Coodinator
Mei-Ling Li
Administrative Coodinator
Janelle Simon
Mouse Colony Manager
Anne Trumble-Koncelik
Lab Manager
Wei Luan
Senior Research Technician
Kasia Rybczyk
Research Technician
Anahi Tehuitzil
Research Technician
Sha Tian
Senior Research Technician
Alexandra Wuest
Research Technician
Sarah Ackermann
Data Coordinator
Publications
- A combinatorial strategy for treating KRAS-mutant lung cancer. Manchado E, Weissmueller S, Morris JP 4th, Chen CC, Wullenkord R, Lujambio A, de Stanchina E, Poirier JT, Gainor JF, Corcoran RB, Engelman JA, Rudin CM, Rosen N, Lowe SW. Nature. 2016 Jun 30;534(7609):647-51. Epub 2016 Jun 22.
- Deletions linked to TP53 loss drive cancer through p53-independent mechanisms. Liu Y, Chen C, Xu Z, Scuoppo C, Rillahan CD, Gao J, Spitzer B, Bosbach B, Kastenhuber ER, Baslan T, Ackermann S, Cheng L, Wang Q, Niu T, Schultz N, Levine RL, Mills AA, Lowe SW. Nature. 2016 Mar 24;531(7595):471-475. doi: 10.1038/nature17157. Epub 2016 Mar 16.
