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The Nikolov laboratory focuses on the structural, biophysical, and biochemical characterization of the molecular mechanisms of cell-cell interactions and signal transduction across the plasma membrane.
The Osorio Lab studies the mechanisms of antibody-mediated immunity, with a focus on myeloid cell reprograming to advance cancer immunotherapies.
The Pillarsetty Laboratory develops bioactive radiopharmaceuticals and fluorophores for molecular characterization and targeted treatment of cancer.
Physician-scientist Adrienne Boire studies metastasis to the central nervous system.
Physician-scientist Richard Kolesnick studies the role of ceramide signaling in radiation-induced vascular dysfunction and tumor regression.
Cell biologist Michael Overholtzer studies the mechanisms of tumor initiation and progression, cell adhesion, and cell death.
We develop and clinically deploy novel computational algorithms for analyzing multiscale, multimodal biomedical imaging data.
Physician-scientist Karuna Ganesh studies stem cell plasticity in metastasis, therapy resistance and tissue regeneration.
The Diehl lab studies how the microbiota and other exogenous factors regulate development and function of the intestinal immune system.
Physician-scientist Adam Schmitt studies how long noncoding RNAs regulate cellular stress responses and tumor development.