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The Baylies laboratory studies the mechanisms that form and maintain muscle both during normal development and in disease.
Molecular biologist Dirk Remus investigates mechanisms of DNA replication in eukaryotic cells.
Physician-scientist Samuel Singer studies the genomic alterations that define new targets for therapy in sarcoma. I am a surgical oncologist who specializes in the diagnosis and treatment of soft tissue sarcoma. I have extensive experience with this group of cancers, and am one of just a few surgeons in the world focused solely on treating sarcoma patients. My years of experience have enabled me to devise surgical techniques that improve the ability to completely remove these tumors. In addition to my clinical sarcoma practice, I conduct laboratory research to develop new methods to improve the diagnosis and treatment of sarcoma. I lead both a National Cancer Institute Specialized Program in Research Excellence (SPORE) and the Sarcoma Genome Project.
Physician-scientist David R. Jones studies molecular mechanisms governing the development of metastases in lung and esophageal cancers.
The Łuksza Lab develops predictive models of immune-driven evolution to understand how tumors and viruses adapt under immune pressure.
Physician-scientist Viviane Tabar focuses on stem cells as tools for brain repair and for modeling brain cancer.
The Kushal Dey lab focuses on developing machine learning models and computational pipelines that integrate genomic and epigenomic data.
Joan Massagué studies the control of stem cell growth and phenotype in tumor progression, metastasis, and response to therapy.
The Hite laboratory studies the mechanisms of ion and metabolite transport and the maintenance of genomic integrity.