Epivir; Epivir HBV
3TC; Apo-Lamivudine; Apo-Lamivudine HBV; Auro-Lamivudine; Heptovir
- This drug may rarely cause swollen liver and an acid health problem in the blood. This may be deadly in some cases. The chance may be higher in women, in overweight people, and in people who have taken drugs like this one for a long time. Talk with your doctor.
- Hepatitis B has gotten worse when this drug was stopped in some people with hepatitis B. Close follow-up for a few months is needed when therapy is stopped in people who have hepatitis B. Do not stop taking this drug without calling your doctor. Talk with your doctor.
- There is more than 1 brand of this drug. One brand cannot safely be used for the other. The doctor will tell you about any needed change.
- Do not take this brand of this drug if you have HIV infection. The dose of this brand is not enough and HIV may be harder to treat after taking it. HIV testing needs to be done before taking this brand. Talk with your doctor.
- It is used to treat hepatitis B infection.
- It is used to treat HIV infection.
- If you have an allergy to lamivudine or any other part of this drug.
- If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
- If you are taking another drug that has the same drug in it.
- Tell all of your health care providers that you take this drug. This includes your doctors, nurses, pharmacists, and dentists.
- Have blood work checked as you have been told by the doctor. Talk with the doctor.
- This drug does not stop the spread of diseases like HIV or hepatitis that are passed through blood or having sex. Do not have any kind of sex without using a latex or polyurethane condom. Do not share needles or other things like toothbrushes or razors. Talk with your doctor.
- If giving to your child, the dose of this drug may need to be changed as your child’s weight changes. Have your child’s weight checked often. Talk with the doctor before changing your child’s dose.
- Tell your doctor if you are pregnant or plan on getting pregnant. You will need to talk about the benefits and risks of using this drug while you are pregnant.
All liquid products:
- If you have high blood sugar (diabetes), you will need to watch your blood sugar closely.
Treating HIV infection:
- If you have HIV and hepatitis B, the hepatitis b virus can change while you take this drug. If this happens, the hepatitis B virus may be harder to treat. Talk with your doctor.
- Liver disease has gotten worse in people who have both HIV and hepatitis C when taking drugs like this one with some other drugs used to treat hepatitis C. Sometimes, this has been deadly. If you have HIV and hepatitis C, talk with your doctor.
- Use this drug with care in children. They may have more side effects. Talk with the doctor.
- This drug is not a cure for HIV. Stay under the care of your doctor.
- When able to, it is best to take the tablet form of this drug. The liquid form of this drug did not work as well in children taking other liquid HIV drugs as it did in children taking the tablet form. Talk with your doctor.
- Do not breast-feed if you have HIV disease unless your doctor tells you to.
Hepatitis B infection:
- Tell your doctor if you have never had hepatitis care before.
- This drug is not a cure for hepatitis infection. Stay under the care of your doctor.
- Tell your doctor if you are breast-feeding. You will need to talk about any risks to your baby.
For all patients taking this drug:
- Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
- Signs of liver problems like dark urine, feeling tired, not hungry, upset stomach or stomach pain, light-colored stools, throwing up, or yellow skin or eyes.
- Signs of too much lactic acid in the blood (lactic acidosis) like fast breathing, fast heartbeat, a heartbeat that does not feel normal, very bad upset stomach or throwing up, feeling very sleepy, shortness of breath, feeling very tired or weak, very bad dizziness, feeling cold, or muscle pain or cramps.
- Signs of a pancreas problem (pancreatitis) like very bad stomach pain, very bad back pain, or very bad upset stomach or throwing up.
- A burning, numbness, or tingling feeling that is not normal.
- Mood changes.
- Change in body fat.
Treating HIV infection:
- This drug may help the immune system work. If you have an infection that you did not know you had, it may show up when you take this drug. Tell your doctor right away if you notice any signs of infection like fever, sore throat, weakness, cough, or shortness of breath after you start this drug.
- Upset stomach or throwing up.
- Loose stools (diarrhea).
- Feeling tired or weak.
- Runny nose.
- Stuffy nose.
- Muscle pain.
- Not able to sleep.
- Nose and throat irritation.
- Ear irritation.
- Take with or without food.
- To gain the most benefit, do not miss doses.
- Keep taking this drug as you have been told by your doctor or other health care provider, even if you feel well.
All liquid products:
- Measure liquid doses carefully. Use the measuring device that comes with this drug. If there is none, ask the pharmacist for a device to measure this drug.
- Take a missed dose as soon as you think about it.
- If it is close to the time for your next dose, skip the missed dose and go back to your normal time.
- Do not take 2 doses at the same time or extra doses.
- Store at room temperature.
- Store in a dry place. Do not store in a bathroom.
- Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
- Check with your pharmacist about how to throw out unused drugs.
- If your symptoms or health problems do not get better or if they become worse, call your doctor.
- Do not share your drugs with others and do not take anyone else’s drugs.
- Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
- Talk with the doctor before starting any new drug, including prescription or OTC, natural products, or vitamins.
- Some drugs may have another patient information leaflet. If you have any questions about this drug, please talk with your doctor, nurse, pharmacist, or other health care provider.
- If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.