Clinical Updates & Insights

Our clinical updates provide you with timely information about Memorial Sloan Kettering’s new treatment approaches, key clinical trials, and innovations in detecting and treating many cancers.

156 Clinical Updates found

Clinical Update

Image-Guided RT Reduces Potential Under-Dosing in High-Risk Prostate Cancer

All radiotherapy treatments for prostate cancer should be accompanied by image-guidance of the prostate position to rule out significant setup errors in fractional delivery.

  • Monday, November 19, 2018

Clinical Update

Profiling Prostate Tumors for MSI May Inform Better Treatment Selection

Profiling prostate cancer tumors for microsatellite instability (MSI) status with targeted next-generation sequencing can identify patients who may respond better to PD-1/PD-L1 agents.

  • Thursday, November 8, 2018

Clinical Update

Prostatectomy and RT Combination Yields Favorable Outcomes in Advanced Prostate Cancer

Men with advanced prostate cancer treated with radical prostatectomy and adjuvant radiotherapy have a lower risk of cancer-specific death and improved overall survival compared to men treated with radiotherapy plus androgen deprivation therapy.

  • Thursday, November 8, 2018

Clinical Update

The Emerging Role and Value of Abbreviated Breast MRI

Abbreviated breast magnetic resonance imaging is a cost-effective screening tool that should be made available to patients with an average lifetime risk of breast cancer, according to our recent review of protocols.

  • Tuesday, October 9, 2018

Clinical Update

Finding a Better Way: Improving the Surgical Paradigm for Ovarian Cancer

Surgical paradigm shifts to achieve complete cytoreduction during primary debulking surgery combined with the use of perioperative epidural anesthesia improve survival outcomes for ovarian cancer patients, our recently published research shows.

  • Monday, October 8, 2018

Clinical Update

Reexamining Surgical Margins in Breast Cancer

Wider negative margins do not improve local control for ductal carcinoma in situ or invasive carcinoma when they are treated with lumpectomy and radiation therapy, our recent literature review shows.

  • Monday, October 8, 2018

Clinical Update

Sidestepping Rectal Cancer Surgery with Total Neoadjuvant Therapy

Total neoadjuvant therapy is a viable treatment strategy for patients with locally advanced rectal cancer and is associated with the potential to sidestep surgical treatment.

  • Monday, September 10, 2018

Clinical Update

The “Pocket-Creation Method” for Resecting Early-Stage Gastrointestinal Cancers

The “pocket-creation method” is the latest advance in endoscopic submucosal dissection, a technique for the removal of early-stage gastrointestinal cancers, further boosting its superiority over the standard approach of using endoscopic mucosal resection.

  • Monday, September 10, 2018

Clinical Update

Distraction Osteogenesis: Optimal Bone Reconstruction in Pediatric Sarcoma

Although distraction osteogenesis is commonly employed in regular orthopedic surgery, its use in cancer patients is currently limited. But research shows that these durable reconstructions can provide superior opportunities for better long-term limb function and growth in this cohort.

  • Friday, August 10, 2018

Clinical Update

Managing Chemotherapy-Induced Thrombocytopenia: Romiplostim Research

Our recent research demonstrates that the thrombopoietin receptor agonist romiplostim effectively modifies chemotherapy-induced thrombocytopenia (CIT) in solid tumor patients, allowing a majority to resume chemotherapy

  • Friday, August 10, 2018