Purinethol [DSC]; Purixan
- It is used to treat a type of leukemia.
- It may be given to you for other reasons. Talk with the doctor.
- If you have an allergy to mercaptopurine or any other part of this drug.
- If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
- If you have taken this drug or a drug called thioguanine before and your cancer did not respond.
- If you are taking allopurinol.
- If you are breast-feeding or plan to breast-feed.
- Tell all of your health care providers that you take this drug. This includes your doctors, nurses, pharmacists, and dentists.
- If you have upset stomach, throwing up, loose stools (diarrhea), or are not hungry, talk with your doctor. There may be ways to lower these side effects.
- You may have more chance of getting an infection. Wash hands often. Stay away from people with infections, colds, or flu.
- You may bleed more easily. Be careful and avoid injury. Use a soft toothbrush and an electric razor.
- If you have thiopurine S-methyltransferase (TPMT) or nucleotide diphosphatase (NUDT15) deficiency, talk with your doctor.
- This drug may add to the chance of getting some types of cancer. Talk with the doctor.
- A rare type of cancer called hepatosplenic T-cell lymphoma (HSTCL) has happened with this drug. These cases have been deadly. Most of the time, these cases happened in teenagers or young adults. Most of these patients were using this drug to treat certain types of bowel problems like Crohn disease and ulcerative colitis. This drug is not approved for use to treat bowel problems like these. Tell the doctor if you have ever had any type of cancer. Talk with the doctor.
- Have blood work checked as you have been told by the doctor. Talk with the doctor.
- If you are taking warfarin, talk with your doctor. You may need to have your blood work checked more closely while you are taking it with this drug.
- Talk with your doctor before getting any vaccines. Use with this drug may either raise the chance of an infection or make the vaccine not work as well.
- You may get sunburned more easily. Avoid sun, sunlamps, and tanning beds. Use sunscreen and wear clothing and eyewear that protects you from the sun.
- A very bad and sometimes life-threatening problem called Macrophage Activation Syndrome (MAS) may rarely happen in people with autoimmune diseases. Talk with the doctor.
- Low blood sugar has happened in people taking this drug, especially children. Signs may be dizziness, headache, feeling sleepy, feeling weak, shaking, a fast heartbeat, confusion, hunger, or sweating. Call your doctor right away if you have any of these signs.
- This drug may cause harm to the unborn baby or loss of the unborn baby if you take it while you are pregnant.
- Use birth control that you can trust to prevent pregnancy while taking this drug.
- If you are pregnant or you get pregnant while taking this drug, call your doctor right away.
- Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
- Signs of infection like fever, chills, very bad sore throat, ear or sinus pain, cough, more sputum or change in color of sputum, pain with passing urine, mouth sores, or wound that will not heal.
- Signs of bleeding like throwing up blood or throw up that looks like coffee grounds; coughing up blood; blood in the urine; black, red, or tarry stools; bleeding from the gums; vaginal bleeding that is not normal; bruises without a reason or that get bigger; or any bleeding that is very bad or that you cannot stop.
- Signs of kidney problems like unable to pass urine, change in how much urine is passed, blood in the urine, or a big weight gain.
- Very loose stools (diarrhea).
- Very upset stomach or throwing up.
- Change in color of skin.
- Redness or white patches in mouth or throat.
- Feeling very tired or weak.
- Shortness of breath.
- Very bad belly pain or soreness.
- A skin lump or growth.
- Very bad and sometimes deadly liver problems have happened with this drug. Call your doctor right away if you have signs of liver problems like dark urine, feeling tired, not hungry, upset stomach or stomach pain, light-colored stools, throwing up, or yellow skin or eyes.
- Loose stools (diarrhea).
- Not hungry.
- Upset stomach or throwing up.
- Feeling tired or weak.
- Take this drug at the same time of day.
- Talk with your doctor or pharmacist about how to take this drug with regard to food.
- Drink lots of noncaffeine liquids unless told to drink less liquid by your doctor.
- Your doctor will tell you how to take this drug. Be sure you know how much to take, how often to take this drug, and how to store this drug. If your doctor does not tell you how to use this drug or if you are not sure how to use it, talk with your doctor.
- You will need to take special care when handling this drug. Check with the doctor or pharmacist to see how to handle this drug.
- Shake well for at least 30 seconds before each use.
- Measure liquid doses carefully. Use the measuring device that comes with this drug.
- Clean the measuring device as you have been told. If you have questions about cleaning the measuring device, talk with the doctor or pharmacist.
- This drug is pink to brown in color. This is normal.
- Call your doctor to find out what to do.
- Store at room temperature.
- Store in a dry place. Do not store in a bathroom.
- Protect from heat.
- Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
- Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.
- Throw away any part not used 8 weeks after opening.
- If your symptoms or health problems do not get better or if they become worse, call your doctor.
- Do not share your drugs with others and do not take anyone else’s drugs.
- Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
- Talk with the doctor before starting any new drug, including prescription or OTC, natural products, or vitamins.
- Some drugs may have another patient information leaflet. If you have any questions about this drug, please talk with your doctor, nurse, pharmacist, or other health care provider.
- If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.