Pediatric Medication

Brand Names: US

Alsuma; Imitrex; Imitrex STATdose Refill; Imitrex STATdose System; Onzetra Xsail; Sumavel DosePro; Zecuity [DSC]; Zembrace SymTouch

Brand Names: Canada

ACT-Sumatriptan; Apo-Sumatriptan; Ava-Sumatriptan; Dom-Sumatriptan; Imitrex DF; Imitrex Injection; Imitrex Nasal Spray; Mylan-Sumatriptan; PHL-Sumatriptan; PMS-Sumatriptan; Sandoz-Sumatriptan; Sumatriptan DF; Taro-Sumatriptan; Teva-Sumatriptan; Teva-Sumatriptan DF

What is this drug used for?

Nose spray, shot, and tablets:

  • It is used to treat migraine headaches.

Nose powder and patch:

  • If your child has been given this form of this drug, talk with the doctor for information about the benefits and risks. Talk with the doctor if you have questions or concerns about giving this drug to your child.

What do I need to tell the doctor BEFORE my child takes this drug?

  • If your child has an allergy to this drug or any part of this drug.
  • If your child is allergic to any drugs like this one or any other drugs, foods, or other substances. Tell the doctor about the allergy and what signs your child had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
  • If your child has any of these health problems: High blood pressure or some types of migraine headaches like hemiplegic or basilar migraine.
  • If your child has ever had any of these health problems: Chest pain or pressure; diseased arteries going to the legs or arms; heart attack; heart disease; poor blood flow in the heart, brain, bowel, or kidney; stroke; or a heartbeat that is not normal like Wolff-Parkinson-White syndrome.
  • If your child has liver disease.
  • If your child has taken certain drugs used for low mood (depression) like isocarboxazid, phenelzine, or tranylcypromine or drugs used for certain other health problems in the last 14 days. Taking this drug within 14 days of those drugs can cause very bad high blood pressure.
  • If your child is taking another drug that has the same drug in it.
  • If your child has taken almotriptan, eletriptan, frovatriptan, naratriptan, rizatriptan, or zolmitriptan in the last 24 hours.
  • If your child has taken ergotamine, methysergide, dihydroergotamine, or any drug like them in the last 24 hours.

If your child is breast-feeding a baby:

  • Talk with the doctor if your child is breast-feeding a baby or plans to breast-feed a baby.
This is not a list of all drugs or health problems that interact with this drug.
Tell the doctor and pharmacist about all of your child’s drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for your child to take this drug with all of his/her drugs and health problems. Do not start, stop, or change the dose of any drug your child takes without checking with the doctor.

What are some things I need to know or do while my child takes this drug?

  • Tell all of your child’s health care providers that your child is taking this drug. This includes your child’s doctors, nurses, pharmacists, and dentists.
  • Have your child avoid tasks or actions that call for alertness until you see how this drug affects your child. These are things like riding a bike, playing sports, or using items such as scissors, lawnmowers, electric scooters, toy cars, or motorized vehicles.
  • Have your child’s blood pressure checked often. Talk with your child’s doctor.
  • Very bad and sometimes deadly allergic side effects have rarely happened. Talk with your child’s doctor.
  • This drug is not meant to prevent or lower the number of migraine headaches your child gets. Talk with the doctor.
  • If your child has a headache that is not like the usual migraine headaches, talk with the doctor before you give this drug.
  • Giving more of this drug (a higher dose, more often) than the doctor told you to give may cause your child’s headaches to become worse.
  • Use care if your child has risks for heart disease (high blood pressure, high cholesterol, overweight, high blood sugar or diabetes, cigarette smoking, other family members with early heart disease). Talk with the doctor.
  • Very bad and sometimes deadly heart problems like heart attack and a heartbeat that is not normal have rarely happened within a few hours of taking this drug. Call the doctor right away if your child has chest, throat, neck, or jaw tightness, pain, pressure, or heaviness; breaking out in a cold sweat; shortness of breath; a fast heartbeat; a heartbeat that does not feel normal; or very bad dizziness or passing out.
  • Very bad and sometimes deadly brain blood vessel problems like stroke have rarely happened with this drug. Call the doctor right away if your child has a change in strength on 1 side that is greater than the other, trouble speaking or thinking, change in balance, or change in eyesight.
  • This drug is not approved for use in children younger than 18 years of age. Talk with the doctor.

If your child is pregnant:

  • Tell the doctor if your child is pregnant or becomes pregnant. You will need to talk about the benefits and risks of your child using this drug while pregnant.

What are some side effects that I need to call my child’s doctor about right away?

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your child’s doctor or get medical help right away if your child has any of the following signs or symptoms that may be related to a very bad side effect:
  • Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
  • Seizures.
  • Loss of eyesight. This can be long-lasting.
  • Very bad headache or if headache is not better after the first dose.
  • A burning, numbness, or tingling feeling that is not normal.
  • Change in color of skin to a bluish color like on the lips, nail beds, fingers, or toes.
  • Hard stools (constipation).
  • Loose stools (diarrhea).
  • Very upset stomach or throwing up.
  • Very bad belly pain or bloody loose stools.
  • Fever.
  • Weight loss.
  • Leg cramps.
  • Feeling of heaviness or tightness in the leg muscles.
  • Feeling cold.
  • Burning or aching pain in the feet or toes.
  • Change in hearing.
  • A very bad and sometimes deadly health problem called serotonin syndrome may happen. The risk may be greater if your child takes this drug with drugs for depression, migraines, or certain other drugs. Call your child’s doctor right away if your child has agitation; change in balance; confusion; hallucinations; fever; a fast or abnormal heartbeat; flushing; muscle twitching or stiffness; seizures; shivering or shaking; sweating a lot; very bad diarrhea, upset stomach, or throwing up; or very bad headache.

What are some other side effects of this drug?

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your child’s doctor or get medical help if any of these side effects or any other side effects bother your child or do not go away:

All products:

  • Dizziness.
  • Flushing.
  • Feeling of warmth.
  • Feeling tired or weak.
  • Feeling sleepy.
  • Upset stomach or throwing up.

Nose spray:

  • Bad taste in your child’s mouth.
  • Burning.
  • Nose and throat irritation.


  • Irritation where the shot is given.
These are not all of the side effects that may occur. If you have questions about side effects, call your child’s doctor. Call your child’s doctor for medical advice about side effects.
You may report side effects to your national health agency.

How is this drug best given?

Give this drug as ordered by your child’s doctor. Read all information given to you. Follow all instructions closely.

All products:

  • Follow how to give this drug as you have been told by your child’s doctor or read the package insert.


  • Give this drug with or without food.
  • Have your child swallow whole. Do not let your child chew, break, or crush.
  • Give this drug with liquids as early as you can after the attack has started.
  • If your child’s headache comes back after the first dose, 1 more dose may be taken 2 hours after the first one.


  • The shot is given under the skin as early as it can be after the attack has started.
  • If you will be giving your child the shot, your child’s doctor or nurse will teach you how to give the shot.
  • Be sure you know where to give the shot. If you are not sure where to give the shot, talk with the doctor.
  • If more than 1 shot is needed, space each shot by 1 hour.
  • Wash hands before and after use.
  • Do not use if the solution is cloudy, leaking, or has particles.
  • Do not use if solution changes color.
  • Throw away needles in a needle/sharp disposal box. Do not reuse needles or other items. When the box is full, follow all local rules for getting rid of it. Talk with a doctor or pharmacist if you have any questions.

Nose spray:

  • Do not give this drug by mouth. Use in your child’s nose only. Keep out of your child’s mouth and eyes (may burn).
  • Use this drug as early as you can after the attack has started.
  • Have your child sit down before use.
  • Have your child blow nose before use.
  • If your child’s headache comes back after the first dose, 1 more dose may be taken 2 hours after the first one.

What do I do if my child misses a dose?

  • This drug is given on an as needed basis. Do not give to your child more often than told by the doctor.

How do I store and/or throw out this drug?

All products:

  • Store at room temperature. Do not refrigerate or freeze.
  • Store in a dry place. Do not store in a bathroom.
  • Protect from light.
  • Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
  • Check with your pharmacist about how to throw out unused drugs.


  • If you were given a storage case, store in the case you were given.

General drug facts

  • If your child’s symptoms or health problems do not get better or if they become worse, call your child’s doctor.
  • Do not share your child’s drug with others and do not give anyone else’s drug to your child.
  • Keep a list of all your child’s drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your child’s doctor.
  • Talk with your child’s doctor before giving your child any new drug, including prescription or OTC, natural products, or vitamins.
  • Some drugs may have another patient information leaflet. If you have any questions about this drug, please talk with your child’s doctor, nurse, pharmacist, or other health care provider.
  • If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

Consumer Information Use and Disclaimer

This information should not be used to decide whether or not to take this medicine or any other medicine. Only the healthcare provider has the knowledge and training to decide which medicines are right for a specific patient. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from the healthcare provider. You must talk with the healthcare provider for complete information about the risks and benefits of using this medicine.

Last Reviewed Date



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