Sloan Kettering Institute (SKI), the laboratory research base of MSKCC, has a professional staff of over 200. At SKI, all approaches, from the most basic and theoretical to the most pragmatic and applied, are utilized in advancing biological knowledge and discovering or improving means for the detection, diagnosis, treatment, and prevention of cancer. The research programs of SKI now occupy about half a million square feet in four buildings: the Kettering Laboratory, the Arnold and Marie Schwartz International Hall of Science for Cancer Research, the Rockefeller Research Laboratories, and the new, 23-story Zuckerman Research Center, which is uniquely designed to foster interaction and collaboration among researchers from different disciplines. Within MSKCC, 31 core facilities such as the Human Tissue Procurement and Tissue Bank, Immunohisto chemistry Laboratory, the Nuclear Magnetic Resonance Analytical Facility, the Radiation Biophysics Facility, and the Monoclonal Antibody Production Facility (in vitro) support basic and clinical research.