Andrew Intlekofer is an Assistant Member in the Human Oncology and Pathogenesis Program and an Attending Physician on the Lymphoma Service in the Department of Medicine. Dr. Intlekofer’s research investigates how deregulated metabolic pathways contribute to cancer development and how metabolic enzymes can be targeted for cancer treatment.
Andrew M. Intlekofer, MD, PhD
Research FocusPhysician-scientist Andrew Intlekofer investigates why cancer cells depend on specific pathways of nutrient metabolism.
EducationMD, PhD, University of Pennsylvania School of Medicine, PA.
- Intlekofer AM, Wang B, Liu H, Shah H, Carmona-Fontaine C, Rustenburg AS, Salah S, Gunner MR, Chodera JD, Cross JR, Thompson CB. L-2-hydroxyglutarate production arises from non-canonical enzyme function at acidic pH. Nature Chemical Biology. 2017 May;13(5):494-500. doi: 10.1038/nchembio.2307.
- Intlekofer AM, Dematteo RG, Venneti S, Finley LWS, Lu C, Judkins AR, Rustenburg AS, Grinaway, PB, Chodera JD, Cross JR, Thompson CB. Hypoxia Induces Production of L-2-Hydroxyglutarate. Cell Metabolism. 2015 Aug 4; 22(2):304-11.
- Burroughs Wellcome Fund Career Award for Medical Scientists (2016)
- NCI K08 Mentored Clinical Scientist Research Career Development Award (2016)
- Steven Greenberg Lymphoma Research Award (MSKCC) (2016)
- Leukemia & Lymphoma Society Special Fellow Award (2015)
- Conquer Cancer Foundation of ASCO Young Investigator Award (2014)
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- Stuart Mudd Award for Excellence and Creativity in Microbiology (UPenn) (2009)
- Saul Winegrad Award for Outstanding Ph.D. Dissertation (UPenn) (2008)
- Balduin Lucke Prize for Research in Experimental Medicine and Biology (UPenn) (2006)