Dissertation Phosphorylation – dependent Regulation of the Tumor Suppressor TRIM3 (2012) Mentor Andrew Koff, PhD Start Year 2008 End Year 2013 Education BA, Princeton University Publications Hukkelhoven E, Liu Y, Yeh N, Ciznadija D, Blain SW, Koff A. (2012). Tyrosine phosphorylation of the p21 cyclin-dependent kinase inhibitor facilitates the development of proneural glioma. J Biol Chem., 287, 38523-30. PMCID: PMC3493897. Gong Y, Zack TI, Morris LG, Lin K, Hukkelhoven E, Raheja R, Tan IL, Turcan S, Veeriah S, Meng S, Viale A, Schumacher SE, Palmedo P, Beroukhim R, Chan TA. (2014) Pan-cancer genetic analysis identifies PARK2 as a master regulator of G1/S cyclins. Nat Genet. 46, 588-94. PMCID: PMC4251771 Raheja R, Liu Y, Hukkelhoven E, Yeh N, Koff A. (2014). The ability of TRIM3 to induce growth arrest depends on RING-dependent E3 ligase activity. Biochem J., 458, 537-45. PMCID: PMC4404499 Liu Y, Raheja R, Yeh N, Ciznadija D, Pedraza AM, Ozawa T, Hukkelhoven E, Erdjument-Bromage H, Tempst P, Gauthier NP, Brennan C, Holland EC, Koff A. (2014). TRIM3, a tumor suppressor linked to regulation of p21(Waf1/Cip1.). Oncogene.33, 308-15. PMCID: PMC3928554
