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Part natural killer, part T cell, this hybrid immune cell has a “double sword” for fighting cancer.
… Tuesday, October 5, 2021 Pick up any immunology textbook and you’ll find an explanation of the “innate” and “adaptive” arms of the immune system. The innate arm is active from birth and responds to a predefined set of common threats; the adaptive arm takes time to develop but is more versatile at combatting
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The new Fiona and Stanley Druckenmiller Center for Lung Cancer Research brings together MSK physicians and scientists in an intensive, multidisciplinary effort against the number-one cause of death from cancer in the nation.
… Friday, January 8, 2016 Summary Lung cancer causes more deaths in the United States than colon, breast, and prostate cancers combined. The Druckenmiller Center gathers scientists and physicians from across MSK to advance our understanding of the disease, examine novel treatments in preclinical models
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Surgical resection of symptomatic, benign intradural extramedullary (IDEM) spine tumors provides rapid, significant, and durable improvements in patient-reported outcomes.
… Tuesday, March 2, 2021 Surgical resection of symptomatic, benign intradural extramedullary (IDEM) spine tumors provides rapid, significant, and durable improvements in patient-reported outcomes (PROs), according to our study published recently in Neurosurgery . (1) Historically, these tumors have been
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Chris Bourne is the first recipient of the MERIT Sawyers Fellowship.
… Thursday, February 10, 2022 Chris Bourne remembers the moment he knew he wanted to become a researcher. He had just completed freshman year at Swarthmore College in Pennsylvania and landed a summer internship with a pharmaceutical company near where he had grown up in South Brunswick, New Jersey. “I’
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Breast conservation therapy as an initial treatment did not compromise survival outcomes compared to mastectomy in breast cancer patients under the age of 35.
… Thursday, January 14, 2021 Survival outcomes in breast cancer patients under the age of 35 was not compromised in those who had initial conservation therapy versus those who had mastectomy, according to our retrospective study published recently in the International Journal of Radiation Oncology . (
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在 35 岁以下的乳腺癌患者中,与乳房切除术相比,保乳手术作为初始疗法并未损害患者的生存结局。
… Thursday, January 14, 2021 根据我们最近发表在 《国际放射肿瘤学杂志》 上的回顾性研究,对于 35 岁以下的乳腺癌患者,相较于接受乳房切除术的患者,接受初始保乳治疗的患者的生存结局并没有更差。 (1) 过去,与老年患者相比,40 岁以下的浸润性乳腺癌女性患者的总生存率 (OS) 更差,复发率更高, (2) , (3) , (4) 因此这些患者接受更高强度的治疗,如乳房切除术(而非保乳手术)联合辅助治疗。 之前的研究也发现,年轻的乳腺癌患者的结局更差。 然而,在这些研究中,研究时间间隔以及对“年轻”或“非常年轻”患者组和老年对照组的定义各不相同,其中一些还包括
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Three 2010 summer students won poster awards at the Annual Biomedical Research Conference for Minority Students in November.
… Wednesday, December 1, 2010 Three 2010 summer students — Jeannie Camarillo, Mariela Martinez Rivera, and Cynthia Sandoval — won poster awards at the Annual Biomedical Research Conference for Minority Students in November. Over 1,200 posters were submitted and only 140 awards presented.
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Carl Granum tells the story of his diagnosis and treatment for a desmoplastic small round cell tumor, a type of sarcoma that typically begins in the abdomen or pelvis.
… Friday, January 19, 2018 Summary Carl Granum was a college athlete in Iowa when he was diagnosed with a desmoplastic small round cell tumor , a type of sarcoma that typically begins in the abdomen or pelvis. In general, sarcomas are cancers in bones, muscles, and connective tissue throughout the body
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— Researchers from Memorial Sloan Kettering Cancer Center (MSK) have shown early promising results in using a chimeric antigen receptor (CAR) T cell therapy that targets the protein mesothelin, which is expressed on the surface of cancer cells in patients with diseases of the chest cavity — namely malignant pleural mesothelioma but also metastatic lung and breast cancer. The results from a phase I clinical trial were presented as part of the press program at the American Association for Cancer Research (AACR) Annual Meeting 2019. The findings showed tumor reduction in patients who participated in the study and no evidence of toxicity.
… Sunday, March 31, 2019 Researchers from Memorial Sloan Kettering Cancer Center (MSK) have shown early promising results in using a chimeric antigen receptor (CAR) T cell therapy that targets the protein mesothelin, which is expressed on the surface of cancer cells in patients with diseases of the chest
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The U.S. Food and Drug Administration (FDA) has granted full approval to the drug tarlatamab, a bispecific T cell engager, for small cell lung cancer, based on results from a phase 3 clinical trial led by Dr. Charles Rudin at MSK.
… Thursday, November 20, 2025 On November 19, 2025, the U.S. Food and Drug Administration (FDA) granted full approval to the targeted immunotherapy drug tarlatamab (Imdelltra ® ) for treating adults with advanced small cell lung cancer (SCLC) that has spread after platinum-based chemotherapy. The approval