Full TitlePAC Protocol: Overnight Fasting After Treatment: The OnFACT Study
Research has shown that cancer survivors are at higher risk for obesity, diabetes, and other medical conditions that have a negative impact on their lives. Although the reasons for the development of these conditions are not fully understood, researchers believe that the health of the gastrointestinal (GI) tract (the body system that processes and breaks down food) may play a major role. Many factors influence the health of the GI tract. The main factors being considered in this study are the body’s processing of blood sugar and the diversity of the microbiome (the number and different types of bacteria normally present in the GI tract).
The purpose of this study is to determine if regularly not eating for at least 12 hours a night (“overnight fasting”) for a six-month period can improve blood sugar and the health of the GI tract in overweight and obese adult survivors of childhood cancer. Researchers propose that increasing the length of the overnight fast will improve blood sugar processing and the diversity of the microbiome.
This study will include overweight or obese adult survivors of childhood cancer who are not already fasting and are being followed in the Memorial Sloan Kettering Adult Long-Term Follow-Up Program. Participants must have completed cancer therapy two or more years before entering the study.
For more information about this study, please contact Dr. Emily Tonorezos at 646-888-8080.