A Study of Exercise Therapy to Improve Cardiovascular Health in Post-Menopausal Women after Treatment for Early-Stage Breast Cancer

Full Title

A Randomized Trial to Minimize Non-Response to Aerobic Training in Post-Menopausal Women with Early Stage Breast Cancer

Purpose

This study will compare the effects of different amounts of aerobic exercise on heart and lung (cardiorespiratory) fitness in post-menopausal women who completed treatment for early-stage breast cancer. Researchers will study the effects of different exercise programs on oxygen use, heart pumping ability, lung function, and blood vessel health. Participants will be randomly assigned to one of four groups:

• Group A: 300 minutes of supervised walking each week for 16 weeks followed by “usual care,” which will not include exercise treatment. Participants will receive monthly check-in calls from the study team until week 32.
• Group B: Supervised walking sessions for 150 minutes each week for 32 weeks.
• Group C: Supervised walking sessions for 300 minutes each week for 32 weeks.
• Group D: Supervised walking sessions for 150 minutes each week for 16 weeks followed by usual care and monthly check-in calls until week 32.