A Phase II Study of Mosunetuzumab as Initial Chemotherapy-Free Treatment for Follicular Lymphoma

Full Title

An Open-Label, Multicenter, Single-Arm, Sequential Phase-2 Study of Mosunetuzumab Alone or With Zanubrutinib for the Treatment of Patients with Newly Diagnosed Follicular Lymphoma in Need of Systemic Therapy

Purpose

The purpose of this study is to assess the safety and effectiveness of the drug mosunetuzumab for people with follicular lymphoma who have not yet received treatment. Mosunetuzumab binds to a cancer cell and a T cell (which plays a key role in the immune system) at the same time. Researchers think that mosunetuzumab may strengthen the immune system’s ability to fight cancer cells by activating a patient’s own cells to destroy the tumor. Mosunetuzumab is given as a subcutaneous (under the skin) injection.

Contact

For more information and to ask about eligibility for this study, please contact the office of Dr. Lorenzo Falchi 646-608-3705.

Protocol
22-100
Phase
Phase II (phase 2)
Disease Status
Newly Diagnosed
Investigator
Co-Investigators
ClinicalTrials.gov ID
NCT05389293