A Phase 1 Study of BDTX-4933 in People With Advanced Lung Cancer

Full Title

A Phase 1/2, Open-label Study of Oral S241656 (BDTX-4933) as Monotherapy and in Combination with Other Anti-Cancer Therapies in Patients with KRAS, BRAF and Other Selected RAS/MAPK Mutation-Positive Malignancies

Purpose

Researchers want to find the best dose of BDTX-4933 to use in people with advanced lung cancer. The people in this study have non-small cell lung cancer that has a mutation (change or variant) in the BRAF or KRAS genes (KRAS non-G12C mutation). This mutation can cause cancer cells to grow.

BDTX-4933 blocks the altered BRAF or KRAS proteins, which play a role in cancer cell growth. By blocking these proteins, BDTX-4933 may help slow or stop the growth of your cancer. It is taken orally (by mouth).

Contact

For more information or to see if you can join this study, please call Dr. Michael Offin’s office at 646-608-3763.