Pictured: Jedd Wolchok

Jedd D. Wolchok, MD, PhD

Medical Oncologist

Titles

Lloyd J. Old/Virginia and Daniel K. Ludwig Chair in Clinical Investigation; Chief, Melanoma & Immunotherapeutics Service; Director, Parker Institute for Cancer Immunotherapy at MSK; Associate Director, Ludwig Center for Cancer Immunotherapy

Clinical Expertise

Melanoma; Immunotherapy and Cancer Vaccines

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Accepted Insurance Providers

Dr. Wolchok accepts the following list of insurance providers. Select your insurance provider to see more details.

Contact and Location

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Find a Convenient Location

Memorial Sloan Kettering has locations throughout New York City, Long Island, New Jersey, and Westchester. These locations offers many services, including screening, chemotherapy, and medical testing.

About Me

Education

MD, New York University

Residencies

Internal Medicine - New York University Medical Center/Bellevue Hospital

Fellowships

Medical Oncology/Hematology - Memorial Sloan Kettering Cancer Center

Board Certifications

Internal Medicine, Medical Oncology

I am a medical oncologist who specializes in caring for people with melanoma. As a researcher, I am working to develop innovative ways to use the immune system to treat cancer. I have been at the forefront of cancer immunotherapy as a clinician-scientist and as a principal investigator of several pivotal clinical trials.

One of these was a large phase III trial that led to the FDA approval of ipilimumab (Yervoy®), an antibody now used as a first-line treatment for people with advanced melanoma. Ipilimumab was the first drug ever shown to improve survival in these patients. It has fundamentally changed this disease’s outcome — people who were once given a matter of months are living years longer in some cases. A number of patients I treated with ipilimumab in 2004 are still alive and free of cancer today. As a physician, nothing is more gratifying than being able to give someone his or her life back after cancer. 

Despite the successes of ipilimumab, only about 20 percent of melanoma patients respond to the drug. This experience led me to test ipilimumab in combination with another immune drug, called nivolumab. I designed and led the phase I, II, and III clinical trials that led to the FDA approval of this combination in 2015 for advanced melanoma. You can hear about one patient’s experience with this combination here.

In 2011, I established the Immunotherapeutics Clinical Core, a specialized phase I outpatient unit at MSK that conducts novel immunotherapy trials, with a specific emphasis on identifying molecular biomarkers that can predict response. This group treats patients with a variety of cancers and has become a model for similar efforts by other major cancer centers throughout the world.

I received my undergraduate degree from Princeton University and my MD and PhD degrees from New York University, where I also fulfilled my residency program. After completing my fellowship at MSK, I remained on the faculty as part of the Melanoma and Immunotherapeutics Service. I am also a professor of medicine at Weill Cornell Medical College.

Awards and Honors

  • The Solomon A. Berson Medical Alumni Achievement Award in Clinical and Translational Science from the NYU School of Medicine, 2016
  • Castle Connolly: New York Magazine Top Doctors (2013-2018)
  • Board of Directors, American Society for Clinical Oncology (ASCO), 2015
  • Dr. Melvin L. and Dr. Sylvia F. Griem Lectureship & Award Recipient (Univ of Chicago), 2015
  • AICF Prize for Scientific Excellence in Medicine Award, 2014
  • Giant of Cancer Care in Melanoma Award, 2014
  • American Association for Cancer Research Richard and Hinda Rosenthal Memorial Award
  • Giants of Cancer Care in Melanoma Award, 2014
  • Virginia and Daniel K. Ludwig Chair for Clinical Investigation, 2013
  • Melanoma International Foundation's Doctor of the Year award, 2012
  • Director, Cancer Vaccine Collaborative, 2011
  • Melanoma Research Foundation – Humanitarian Award
  • 2010
  • Damon Runyon-Lilly Clinical Investigator Award, 2008

Colleagues

Doctors at Memorial Sloan Kettering work as teams, with specialists from all different areas. This allows us to consider all your needs together, and to give you the best possible care.

Clinical Trials

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Find a Clinical Trial for You

Memorial Sloan Kettering's doctors and scientists are constantly developing new treatments for cancer. MSK is typically running hundreds of clinical trials at a given time.

You may be able to participate in a clinical trial even if you are new to MSK. Search our online directory to find trial information and see more about who can participate.

Research and Publications

View Dr. Wolchok's Lab

Publications on PubMed

Visit PubMed for a full listing of Dr. Wolchok’s journal articles. Pubmed is an online index of research papers and other articles from the US National Library of Medicine and the National Institutes of Health.