Docefrez [DSC]; Taxotere
Docetaxel for Injection; Docetaxel Injection; Taxotere
- Very bad and sometimes deadly allergic reactions have happened with this drug. Be sure your child does not get this drug if your child has ever had an allergic reaction to this drug or to other drugs that have polysorbate 80 in them.
- The risk of death that may rarely happen with this drug is raised in people with liver problems and in people who get high doses of this drug. The risk is also raised in people with a certain type of lung cancer who have been treated with certain chemo drugs in the past. Be sure your child does not get this drug if your child has liver disease. Talk with the doctor.
- This drug may cause your child to swell or keep fluid in his/her body. Tell your child’s doctor if he/she has swelling, weight gain, or trouble breathing after this drug is given.
- This drug may lower the ability of the bone marrow to make blood cells that the body needs. This can lead to needing a blood transfusion and very bad and sometimes deadly bleeding problems or infections. Tell the doctor right away if your child has signs of infection like fever, chills, or sore throat; any bruising or bleeding; or if your child feels very tired or weak.
- Be sure your child does not get this drug if your child has a low white blood cell count.
- Have your child’s blood work checked often. Talk with your child’s doctor.
- It is used to treat cancer.
- If your child has an allergy to this drug or any part of this drug.
- If your child is allergic to any drugs like this one or any other drugs, foods, or other substances. Tell the doctor about the allergy and what signs your child had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
If your child is breast-feeding a baby:
- Talk with the doctor if your child is breast-feeding a baby or plans to breast-feed a baby.
- Tell all of your child’s health care providers that your child is taking this drug. This includes your child’s doctors, nurses, pharmacists, and dentists.
- Your child may have more chance of getting infections. Avoid crowds and people with infections, colds, or flu.
- If your child has an upset stomach or loose stools (diarrhea), is throwing up, or is not hungry, talk with the doctor. There may be ways to lower these side effects.
- The doctor may start your child on a drug to help with swelling.
- Talk with the doctor before your child gets any vaccines. Use with this drug may either raise the chance of very bad infection or make the vaccine not work as well.
- Your child may bleed more easily. Make sure your child is careful and avoids injury. Be sure your child has a soft toothbrush.
- This drug may add to the chance of getting some types of cancer. Talk with the doctor.
- Hair loss is common with this drug. Most of the time, normal hair growth has come back. Sometimes, hair growth has not gone back to normal. Talk with the doctor.
If your child is or may be sexually active:
- Have your child use birth control to prevent pregnancy while taking this drug.
If your child is pregnant:
- This drug may cause harm to the unborn baby if your child takes it during pregnancy. If your child is pregnant or gets pregnant while taking this drug, call the doctor right away.
Products that contain alcohol:
- Have your child avoid tasks or actions that call for alertness for 1 to 2 hours after getting this drug and until you see how this drug affects your child. These are things like riding a bike, playing sports, or using items such as scissors, lawnmowers, electric scooters, toy cars, or motorized vehicles.
- This drug has alcohol in it. This may cause your child to feel drunk during and after treatment. Tell the doctor if your child has confusion, feels drunk, stumbles, or feels very sleepy during treatment or within 1 to 2 hours after treatment.
- Alcohol may interact with this drug. Be sure your child does not drink alcohol.
- Talk with the doctor before giving your child other drugs and natural products that may slow your child’s actions.
- Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
- Signs of infection like fever, chills, very bad sore throat, ear or sinus pain, cough, more sputum or change in color of sputum, pain with passing urine, mouth sores, or wound that will not heal.
- Signs of bleeding like throwing up blood or throw up that looks like coffee grounds; coughing up blood; blood in the urine; black, red, or tarry stools; bleeding from the gums; vaginal bleeding that is not normal; bruises without a reason or that get bigger; or any bleeding that is very bad or that you cannot stop.
- Signs of liver problems like dark urine, feeling tired, not hungry, upset stomach or stomach pain, light-colored stools, throwing up, or yellow skin or eyes.
- Shortness of breath, a big weight gain, or swelling in the arms or legs.
- Very bad dizziness or passing out.
- Very upset stomach or throwing up.
- A burning, numbness, or tingling feeling that is not normal.
- Feeling very tired or weak.
- Chest pain or pressure or a fast heartbeat.
- A heartbeat that does not feel normal.
- Very bad headache.
- Muscle pain.
- This drug may cause tissue damage if the drug leaks from the vein. Tell your child’s nurse if your child has any redness, burning, pain, swelling, blisters, skin sores, or leaking of fluid where the drug is going into your child’s body.
- This drug may cause a certain eye problem called cystoid macular edema (CME). Your child may need to have eye exams while using this drug. Call your child’s doctor right away if your child has a change in eyesight like blurred eyesight or loss of eyesight.
- Upset stomach or throwing up.
- Loose stools (diarrhea).
- Mouth irritation or mouth sores.
- Feeling tired or weak.
- Hair loss.
- Change in nails.
- Change in taste.
- Hard stools (constipation).
- Not hungry.
- Joint pain.
- Eye redness.
- It is given as an infusion into a vein over a period of time.
- A steroid drug like dexamethasone will be given before this drug to lower side effects. Talk with the doctor. Tell the doctor if the steroid drug is not used as your doctor has told you.
- Call your child’s doctor to find out what to do.
- If you need to store this drug at home, talk with your child’s doctor, nurse, or pharmacist about how to store it.
- If your child’s symptoms or health problems do not get better or if they become worse, call your child’s doctor.
- Do not share your child’s drug with others and do not give anyone else’s drug to your child.
- Keep a list of all your child’s drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your child’s doctor.
- Talk with your child’s doctor before giving your child any new drug, including prescription or OTC, natural products, or vitamins.
- Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
- Check with your pharmacist about how to throw out unused drugs.
- Some drugs may have another patient information leaflet. If you have any questions about this drug, please talk with your child’s doctor, nurse, pharmacist, or other health care provider.
- If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.