Granix; Neupogen; Zarxio
- It is used to lower the chance of getting an infection in cancer patients who have had very bad bone marrow problems caused by chemo.
- It is used to raise the number of stem cells.
- It is used to treat low white blood cell counts.
- It may be given to you for other reasons. Talk with the doctor.
- If you have an allergy to filgrastim or any other part of this drug.
- If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
- Tell dentists, surgeons, and other doctors that you use this drug.
- Do not get this drug on the same day that you are getting chemo or radiation.
- Some people with sickle cell disease have had times where the sickle cell disease has gotten worse when taking this drug. Sometimes, this has been deadly. Talk with the doctor.
- Have blood work checked as you have been told by the doctor. Talk with the doctor.
- This drug may cause a very bad and sometimes deadly problem called capillary leak syndrome (CLS). CLS may lead to low blood pressure and harm to the organs. It may also lead to a heartbeat that is not normal, chest pain or pressure, heart attack, lung or breathing problems, bleeding or lower blood flow in the stomach or bowel, kidney problems, swelling, or change in thinking clearly and with logic. Talk with the doctor.
- This drug may affect certain lab tests. Be sure your doctor and lab workers know you take this drug.
- Tell your doctor if you are pregnant or plan on getting pregnant. You will need to talk about the benefits and risks of using this drug while you are pregnant.
- Tell your doctor if you are breast-feeding. You will need to talk about any risks to your baby.
Neupogen® and Zarxio®:
- If you have a latex allergy, talk with your doctor. Some products have latex.
- Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
- Signs of kidney problems like unable to pass urine, change in how much urine is passed, blood in the urine, or a big weight gain.
- Dark urine.
- A fast heartbeat.
- A heartbeat that does not feel normal.
- Dizziness or passing out.
- Sweating a lot.
- Shortness of breath.
- Fast breathing.
- Coughing up blood.
- Feeling very tired or weak.
- Any bruising or bleeding that is not normal.
- Very bad irritation where the shot was given.
- Purple spots or redness of the skin.
- Very bad headache.
- Swelling of belly.
- Enlarged and ruptured spleens have happened with this drug. Sometimes, ruptured spleens have been deadly. Call your doctor right away if you have left upper stomach pain or left shoulder pain.
- Back pain.
- Bone pain.
- Joint pain.
- Upset stomach.
- Irritation where the shot is given.
- It is given as a shot into the fatty part of the skin.
- You will be watched closely by your doctor.
- Your doctor may teach you how to give the shot.
- Follow how to use as you have been told by the doctor or read the package insert.
- Take as you have been told, even if you feel well.
- To gain the most benefit, do not miss doses.
- Do not shake the solution.
- Take this drug at the same time of day.
- Before using this drug, take it out of the refrigerator and leave it at room temperature for 30 minutes.
- Wash your hands before and after use.
- Do not use if the solution is cloudy, leaking, or has particles.
- Do not use if solution changes color.
- Do not give into skin that is irritated, bruised, red, infected, or scarred.
- Move the site where you give the shot with each shot.
- Throw syringe away after use. Do not use more than one time.
- Throw away needles in a needle/sharp disposal box. Do not reuse needles or other items. When the box is full, follow all local rules for getting rid of it. Talk with a doctor or pharmacist if you have any questions.
Neupogen® and Zarxio®:
- It may be given as a shot into a vein.
- If you get this drug on the skin, wash it off right away with soap and water.
- If you get this drug in the eyes, flush right away with cool water and get medical help.
- Call the doctor to find out what to do.
- Store in a refrigerator. Do not freeze.
- Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
- Check with your pharmacist about how to throw out unused drugs.
Neupogen® and Zarxio®:
- Protect from light.
- If this drug freezes, let it thaw in the refrigerator before the dose.
- Do not use if this drug has been frozen more than once.
- If needed, this drug can be left out at room temperature for up to 24 hours.
- Throw away unopened drug if left at room temperature for more than 24 hours.
- Store in the carton to protect from light.
- If needed, this drug can be left out at room temperature for up to 5 days. If not used within 5 days of being left out at room temperature, you can return this drug to the refrigerator. Do not do this more than 1 time.
- Throw away unopened drug if left at room temperature for more than 5 days.
- If your symptoms or health problems do not get better or if they become worse, call your doctor.
- Do not share your drugs with others and do not take anyone else’s drugs.
- Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
- Talk with the doctor before starting any new drug, including prescription or OTC, natural products, or vitamins.
- Some drugs may have another patient information leaflet. If you have any questions about this drug, please talk with your doctor, nurse, pharmacist, or other health care provider.
- If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
If you have any questions or concerns, talk with a member of your healthcare team. You can reach them Monday through Friday from 9:00 am to 5:00 pm at ____________________. After 5:00 pm, during the weekend, and on holidays, please call____________________. If there’s no number listed, or you’re not sure, call 212-639-2000.
Filgrastim©2016 Memorial Sloan Kettering Cancer Center - Generated on February 5, 2016