- This drug may lower the ability of the bone marrow to make blood cells that the body needs. This can lead to needing a blood transfusion and very bad and sometimes deadly bleeding problems or infections. Tell the doctor right away if your child has signs of infection like fever, chills, or sore throat; any bruising or bleeding; or if your child feels very tired or weak.
- Have blood work checked as you have been told by the doctor. Talk with the doctor.
- This drug may raise the chance of getting cancer. A type of cancer called leukemia and skin cancer have happened in people taking this drug for a long time. Your child will need to have regular check-ups. The doctor will tell you how often your child needs to have these. Talk with the doctor.
- Have your child avoid lots of sun, sunlamps, and tanning beds. Use sunscreen and dress your child in clothing and eyewear that protects him/her from the sun.
- It is used to treat sickle cell anemia.
- It is used to treat a type of leukemia.
- It is used to treat cancer of the head and neck.
- It may be given to your child for other reasons. Talk with the doctor.
- If your child has an allergy to this drug or any part of this drug.
- If your child is allergic to any drugs like this one or any other drugs, foods, or other substances. Tell the doctor about the allergy and what signs your child had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
- If your child has any of these health problems: Anemia (other than sickle cell anemia); bone marrow problems like low platelet count, low red blood cell count, or low white blood cell count; or wounds on the legs (leg ulcers).
- If your child is taking any of these drugs: Didanosine or stavudine.
If your child is breast-feeding a baby:
- Be sure your child does not breast-feed a baby while taking this drug.
- Tell all of your child’s health care providers that your child is taking this drug. This includes your child’s doctors, nurses, pharmacists, and dentists.
- Your child may have more chance of getting infections. Have your child wash hands often. Avoid crowds and people with infections, colds, or flu.
- Your child may bleed more easily. Make sure your child is careful and avoids injury. Be sure your child has a soft toothbrush.
- This drug may affect certain lab tests. Tell all of your child’s health care providers and lab workers that your child takes this drug.
- Talk with the doctor before your child gets any vaccines. Use with this drug may either raise the chance of very bad infection or make the vaccine not work as well.
- In people who have HIV, very bad and sometimes deadly pancreas, liver, and nerve problems have happened when this drug was taken with certain other drugs. Talk with the doctor.
- If your child has had or will be having radiation treatment, talk with the doctor. Worse side effects from radiation treatment have happened with this drug.
- Allergic reactions have happened with this drug. Sometimes, these have been very bad and people have had to go to the hospital. Talk with the doctor.
- This drug may affect sperm in males. This may affect being able to father a child later in life. Talk with the doctor.
- If your child is of childbearing age, a pregnancy test will need to be done before starting this drug to make sure she is not pregnant.
If your child is or may be sexually active:
- Have your child use birth control to prevent pregnancy while taking this drug and for 6 months after stopping this drug.
- If your child is a male and has sex with a female who could get pregnant, they must prevent pregnancy during care and for some time after care ends. Talk with the doctor to see how long they must use birth control after your child stops this drug.
- If your child is a male and his sex partner gets pregnant while he takes this drug or within several months after his last dose, call the doctor right away.
If your child is pregnant:
- This drug may cause harm to the unborn baby if your child takes it during pregnancy.
- If your child gets pregnant while taking this drug or within 6 months after her last dose, call the doctor right away.
- Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
- Signs of infection like fever, chills, very bad sore throat, ear or sinus pain, cough, more sputum or change in color of sputum, pain with passing urine, mouth sores, or wound that will not heal.
- Signs of bleeding like throwing up blood or throw up that looks like coffee grounds; coughing up blood; blood in the urine; black, red, or tarry stools; bleeding from the gums; vaginal bleeding that is not normal; bruises without a reason or that get bigger; or any bleeding that is very bad or that you cannot stop.
- Feeling very tired or weak.
- Change in color or size of a mole.
- A skin lump or growth.
- Change in skin or finger nails.
- Skin ulcers and dead body tissue (gangrene) has happened with this drug. Call your child’s doctor right away if your child has skin ulcers or any other skin changes.
- Upset stomach.
- Loose stools (diarrhea).
- Hard stools (constipation).
- Not hungry.
- Hair loss.
- Mouth sores.
- Weight gain.
- Give this drug at the same time of day.
- Give this drug with or without food.
- Give this drug with a full glass of water.
- Wash your hands before and after use.
- To gain the most benefit, do not miss giving your child doses.
- Keep giving this drug to your child as you have been told by your child’s doctor or other health care provider, even if your child feels well.
- You will need to take special care when handling this drug. Check with the doctor or pharmacist to see how to handle this drug.
- Wear gloves when touching this drug.
- Have your child swallow whole. Do not let your child chew or crush.
- Do not open the capsules.
- If the capsule is opened or broken, do not touch the contents. If the contents are touched or they get in the eyes, wash hands or eyes right away.
- The 1000 mg tablets may be split. If using 100 mg tablets, do not split the tablets into smaller parts.
- If your child cannot swallow tablets, they can be dissolved in a small amount of water in a teaspoon. After mixing, give the dose right away. Do not store for future use.
- If a tablet is crushed, do not touch it. If a crushed tablet is touched or gets it in the eyes, wash hands or eyes right away.
- Give a missed dose as soon as you think about it.
- If it is close to the time for your child’s next dose, skip the missed dose and go back to your child’s normal time.
- Do not give 2 doses at the same time or extra doses.
- Store at room temperature.
- Keep lid tightly closed.
- Store in a dry place. Do not store in a bathroom.
- Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
- Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.
- You must handle and throw away this drug the right way. If powder from the capsule is spilled, wipe it up with a damp paper towel. Throw away the towel and the empty capsules in a closed holder, such as a plastic bag. Wash your hands fully.
- If using the 1000 mg tablets and you have split them, store the smaller parts in the bottle. Use the smaller parts within 3 months.
- You must handle and throw away this drug the right way. If powder from a broken tablet is spilled, wipe it up with a damp paper towel. Throw away the towel in a closed holder, such as a plastic bag. Wash your hands fully.
- If your child’s symptoms or health problems do not get better or if they become worse, call your child’s doctor.
- Do not share your child’s drug with others and do not give anyone else’s drug to your child.
- Keep a list of all your child’s drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your child’s doctor.
- Talk with your child’s doctor before giving your child any new drug, including prescription or OTC, natural products, or vitamins.
- Some drugs may have another patient information leaflet. If you have any questions about this drug, please talk with your child’s doctor, nurse, pharmacist, or other health care provider.
- If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.