Ipratropium and Albuterol

Adult Medication

Brand Names: US

Combivent Respimat; Combivent [DSC]; DuoNeb [DSC]

Brand Names: Canada

Apo-Salvent-Ipravent Sterules; Combivent Respimat; Combivent UDV; ratio-Ipra Sal UDV; Teva-Combo Sterinebs

What is this drug used for?

  • It is used to open the airways in lung diseases where spasm may cause breathing problems.

What do I need to tell my doctor BEFORE I take this drug?

  • If you have an allergy to ipratropium, albuterol, or any other part of this drug.
  • If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
  • If you are breast-feeding or plan to breast-feed.
This drug may interact with other drugs or health problems.
Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take this drug with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.

What are some things I need to know or do while I take this drug?

  • Tell all of your health care providers that you take this drug. This includes your doctors, nurses, pharmacists, and dentists.
  • Avoid driving and doing other tasks or actions that call for you to be alert or have clear eyesight until you see how this drug affects you.
  • Do not take more of this drug or use it more often than you have been told. Deaths have happened when too much of this drug was taken. Talk with your doctor.
  • Call your doctor right away if your normal dose does not work well, if your signs get worse, or if you need to use this drug more often than normal.
  • Tell your doctor if you are pregnant or plan on getting pregnant. You will need to talk about the benefits and risks of using this drug while you are pregnant.

What are some side effects that I need to call my doctor about right away?

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:
  • Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
  • Signs of low potassium levels like muscle pain or weakness, muscle cramps, or a heartbeat that does not feel normal.
  • Signs of high blood pressure like very bad headache or dizziness, passing out, or change in eyesight.
  • Chest pain or pressure or a fast heartbeat.
  • A heartbeat that does not feel normal.
  • If you are not able to get the breathing attack under control. Get help right away.
  • Peak flow measurement low.
  • Very nervous and excitable.
  • Change in eyesight, eye pain, or very bad eye irritation.
  • Seeing halos or bright colors around lights.
  • Trouble passing urine.
  • This drug can cause very bad breathing problems right after you take a dose. Sometimes, this may be life-threatening. If you have trouble breathing, breathing that is worse, wheezing, or coughing after using this drug, use a rescue inhaler and get medical help right away.

What are some other side effects of this drug?

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:
  • Feeling nervous and excitable.
  • Headache.
  • Shakiness.
These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.
You may report side effects to your national health agency.

How is this drug best taken?

Use this drug as ordered by your doctor. Read all information given to you. Follow all instructions closely.

All products:

  • Follow how to use as you have been told by the doctor or read the package insert.
  • Do not get this drug in the eyes.

Puffer (inhaler):

  • For breathing into the lungs.
  • Prepare before first use or when puffer has not been used for more than 21 days. Spray towards the ground until mist is seen. Once the mist is seen, repeat 3 more times. If it has been more than 3 days since it has been used, spray once at the ground.
  • After all sprays have been used, the puffer (inhaler) will lock.
  • Put the cap back on after you are done using your dose.
  • If using more than 1 type of puffer (inhaler), ask the doctor which puffer to use first.
  • Have your puffer (inhaler) use checked with your doctor at each visit. Read and follow facts on how to use the puffer. Make sure you use the puffer the right way.

Liquid for breathing in:

  • For breathing in only as a liquid (solution) by a special machine (nebulizer) into the lungs.
  • Do not use if the solution is cloudy, leaking, or has particles.
  • Do not use if solution changes color.
  • Do not mix other drugs in nebulizer.

What do I do if I miss a dose?

  • If you use this drug on a regular basis, use a missed dose as soon as you think about it.
  • If it is close to the time for your next dose, skip the missed dose and go back to your normal time.
  • Do not use 2 doses at the same time or extra doses.
  • Many times this drug is used on an as needed basis. Do not use more often than told by the doctor.

How do I store and/or throw out this drug?

All products:

  • Store at room temperature. Do not freeze.
  • Protect from light.
  • Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
  • Check with your pharmacist about how to throw out unused drugs.

Puffer (inhaler):

  • Throw away after 3 months from first use or after the most number of sprays have been used, whichever comes first, even if it feels like there is more drug in the can.

Liquid for breathing in:

  • Store unused containers in foil pouch until use.
  • Check how long vials may be stored once the pouch has been opened.

General drug facts

  • If your symptoms or health problems do not get better or if they become worse, call your doctor.
  • Do not share your drugs with others and do not take anyone else’s drugs.
  • Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
  • Talk with the doctor before starting any new drug, including prescription or OTC, natural products, or vitamins.
  • Some drugs may have another patient information leaflet. If you have any questions about this drug, please talk with your doctor, nurse, pharmacist, or other health care provider.
  • If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

Consumer Information Use and Disclaimer

This information should not be used to decide whether or not to take this medicine or any other medicine. Only the healthcare provider has the knowledge and training to decide which medicines are right for a specific patient. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from the healthcare provider. You must talk with the healthcare provider for complete information about the risks and benefits of using this medicine.

Last Reviewed Date



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