This information from Lexicomp® explains what you need to know about this medication, including what it’s used for, how to take it, its side effects, and when to call your healthcare provider.
- This drug may raise the chance of some lung or breathing problems like coughing up blood or trouble breathing. Sometimes, lung problems have gotten worse in people who already have them and have needed to be treated in a hospital. Call your doctor right away if you have any new or worse lung or breathing problems like coughing up blood, fast breathing, shortness of breath, wheezing or other trouble breathing, cough, or fever.
- It is used to treat a type of bacterial infection.
- If you are allergic to this drug; any part of this drug; or any other drugs, foods, or substances. Tell your doctor about the allergy and what signs you had.
- If you are taking any of these drugs: Ethacrynic acid, furosemide, mannitol, or urea.
- If you are taking or have recently taken any drugs that can cause nerve, kidney, or hearing problems. This may be drugs like amphotericin B, bacitracin, cephaloridine, cisplatin, colistin, cyclosporine, paromomycin, polymyxin B, vancomycin, viomycin, or other drugs like this one. There are many other drugs that can do this. Ask your doctor or pharmacist if you are not sure.
This is not a list of all drugs or health problems that interact with this drug.
Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take this drug with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.
- Tell all of your health care providers that you take this drug. This includes your doctors, nurses, pharmacists, and dentists.
- Allergic reactions have happened with this drug. Rarely, some reactions can be very bad or life-threatening. Talk with the doctor.
- Have blood work checked as you have been told by the doctor. Talk with the doctor.
- Have a hearing test before starting this drug and while you take this drug.
- Muscle weakness has happened with drugs like this one. If you have nerve or muscle problems like myasthenia gravis, talk with your doctor. Call your doctor right away if you have any muscle weakness.
- Do not use longer than you have been told. A second infection may happen.
- This drug may cause harm to the unborn baby if you take it while you are pregnant. If you are pregnant or you get pregnant while taking this drug, call your doctor right away.
- Tell your doctor if you are breast-feeding. You will need to talk about any risks to your baby.
WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:
- Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
- Signs of kidney problems like unable to pass urine, change in how much urine is passed, blood in the urine, or a big weight gain.
- Change in balance.
- Dizziness or passing out.
- Ringing in the ears, hearing loss, or any other changes in hearing.
- Trouble speaking.
- Chest pain or pressure or a fast heartbeat.
- Diarrhea, upset stomach, or throwing up.
- Stomach pain or cramps.
- Not able to control stools or urine.
- High-pitched abnormal breathing sound.
All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:
- Change in voice.
- Mouth or throat pain or irritation.
- Back, muscle, or joint pain.
- Feeling tired or weak.
- Weight loss.
- More sputum.
These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.
You may report side effects to your national health agency.
Use this drug as ordered by your doctor. Read all information given to you. Follow all instructions closely.
- For breathing in only as a liquid (solution) by a special machine (nebulizer) into the lungs.
- Only use the type of nebulizer that you have been told to use. If you are not sure what type of nebulizer to use, talk with the doctor.
- If stored in a refrigerator, let this drug come to room temperature before using it. Leave it at room temperature for at least 45 minutes. Do not heat this drug.
- Before use, shake the vial for at least 10 to 15 seconds until contents are mixed well.
- Use right after opening.
- Throw away any part of opened vial not used after use.
- Keep using this drug as you have been told by your doctor or other health care provider, even if you feel well.
- If you are taking more than 1 inhaled drug, talk to your doctor about the best order for taking your drugs.
- Skip the missed dose and go back to your normal time.
- Do not take 2 doses at the same time or extra doses.
- Store in a refrigerator. Do not freeze.
- Do not use if it has been frozen.
- You may store unopened vials at room temperature. If you store at room temperature, throw away any part not used after 28 days.
- Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
- Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.
- If your symptoms or health problems do not get better or if they become worse, call your doctor.
- Do not share your drugs with others and do not take anyone else’s drugs.
- Some drugs may have another patient information leaflet. If you have any questions about this drug, please talk with your doctor, nurse, pharmacist, or other health care provider.
- This drug comes with an extra patient fact sheet called a Medication Guide. Read it with care. Read it again each time this drug is refilled. If you have any questions about this drug, please talk with the doctor, pharmacist, or other health care provider.
- If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
© 2022 UpToDate, Inc. and its affiliates and/or licensors. All rights reserved.