This information from Lexicomp® explains what you need to know about this medication, including what it’s used for, how to take it, its side effects, and when to call your healthcare provider.
Brand Names: US
Brand Names: Canada
What is this drug used for?
- It is used to treat cancer.
What do I need to tell the doctor BEFORE my child takes this drug?
- If your child is allergic to this drug; any part of this drug; or any other drugs, foods, or substances. Tell the doctor about the allergy and what signs your child had.
- If your child is taking any of these drugs: Lenalidomide, pomalidomide, or thalidomide.
If your child is breast-feeding a baby:
- Be sure your child does not breast-feed a baby while taking this drug and for 4 months after the last dose.
This is not a list of all drugs or health problems that interact with this drug.
Tell the doctor and pharmacist about all of your child’s drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe to give this drug with all of your child’s other drugs and health problems. Do not start, stop, or change the dose of any drug your child takes without checking with the doctor.
What are some things I need to know or do while my child takes this drug?
- Tell all of your child’s health care providers that your child is taking this drug. This includes your child’s doctors, nurses, pharmacists, and dentists.
- Have blood work checked as you have been told by the doctor. Talk with the doctor.
- This drug may cause very bad side effects. Sometimes these have been life-threatening or deadly. These may happen in the lungs, bowels, liver, kidney, pituitary gland, thyroid gland, or other parts of the body. If you have questions, talk with the doctor.
- If your child has high blood sugar (diabetes), talk with the doctor. This drug can raise blood sugar.
- Check your child’s blood sugar as you have been told by the doctor.
- Infusion reactions have happened with this drug. Sometimes, these could be very bad or life-threatening. Talk with the doctor.
- If your child has had an organ transplant, talk with your child’s doctor. This drug may raise the chance of organ transplant rejection.
- If your child is having or has had a stem cell transplant with stem cells from someone else (allogeneic), talk with your child’s doctor. Some problems with these types of stem cell transplants have happened in people who have had this drug. These problems can be very bad and can lead to death.
- If your child is of childbearing age, a pregnancy test will need to be done before starting this drug to make sure your child is not pregnant.
If your child is or may be sexually active:
- This drug may cause harm to the unborn baby if your child takes it during pregnancy.
- Have your child use birth control while taking this drug and for some time after the last dose. Ask the doctor how long your child must use birth control. If your child becomes pregnant, call the doctor right away.
What are some side effects that I need to call my child’s doctor about right away?
WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your child’s doctor or get medical help right away if your child has any of the following signs or symptoms that may be related to a very bad side effect:
- Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
- Signs of high blood sugar like confusion, feeling sleepy, unusual thirst or hunger, passing urine more often, flushing, fast breathing, or breath that smells like fruit.
- Signs of low blood sugar like dizziness, headache, feeling sleepy, feeling weak, shaking, a fast heartbeat, confusion, hunger, or sweating.
- Signs of liver problems like dark urine, tiredness, decreased appetite, upset stomach or stomach pain, light-colored stools, throwing up, or yellow skin or eyes.
- Signs of kidney problems like unable to pass urine, change in how much urine is passed, blood in the urine, or a big weight gain.
- Signs of thyroid, pituitary, or adrenal gland problems like change in mood or behavior, change in weight or taste, constipation, deeper voice, dizziness, fainting, feeling cold, feeling very tired, hair loss, severe or long-lasting headache, change in sex interest, eye problems, fast heartbeat, more sweating, fast or deep breathing, sweet smelling breath, change in smell of urine or sweat, or passing urine more often.
- Signs of bowel problems (such as colitis) like black, tarry, or bloody stools; fever; mucus in the stools; throwing up blood or throw up that looks like coffee grounds; or severe stomach pain, constipation, or diarrhea.
- Signs of electrolyte problems like mood changes; confusion; muscle pain, cramps, or spasms; weakness; shakiness; change in balance; an abnormal heartbeat; seizures; loss of appetite; or severe upset stomach or throwing up.
- Signs of lung or breathing problems like shortness of breath or other trouble breathing, cough, or fever.
- Signs of a brain problem like change in balance, feeling confused, fever, memory problems, muscle weakness, seizures, stiff neck, or very upset stomach or throwing up.
- Signs of a spinal cord problem (myelitis) like pain, numbness, tingling, or weakness in the arms or legs; bladder problems like passing urine more often, leaking of urine, or trouble passing urine; or bowel problems like severe constipation.
- Chest pain or pressure.
- Fast or abnormal heartbeat.
- Fever, chills, or sore throat; any unexplained bruising or bleeding; or feeling very tired or weak.
- Change in eyesight, eye pain, or severe eye irritation.
- Swollen gland.
- Dizziness or passing out.
- Sweating a lot.
- A burning, numbness, or tingling feeling that is not normal.
- Not able to move.
- White patches on the skin.
- A severe skin reaction (Stevens-Johnson syndrome/toxic epidermal necrolysis) may happen. It can cause severe health problems that may not go away, and sometimes death. Get medical help right away if your child has signs like red, swollen, blistered, or peeling skin (with or without fever); red or irritated eyes; or sores in the mouth, throat, nose, or eyes.
What are some other side effects of this drug?
All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your child’s doctor or get medical help if any of these side effects or any other side effects bother your child or do not go away:
- Feeling tired or weak.
- Back, bone, joint, or muscle pain.
- Decreased appetite.
- Stomach pain.
- Weight loss.
- Hair loss.
- Change in taste.
- Trouble sleeping.
- Signs of a common cold.
- Flu-like signs.
- Constipation, diarrhea, throwing up, and upset stomach are common with this drug. If these happen, talk with your child’s doctor about ways to lower these side effects. Call your child’s doctor right away if any of these effects bother your child, do not go away, or are severe.
These are not all of the side effects that may occur. If you have questions about side effects, call your child’s doctor. Call your child’s doctor for medical advice about side effects.
You may report side effects to your national health agency.
How is this drug best given?
Give this drug as ordered by your child’s doctor. Read all information given to you. Follow all instructions closely.
- It is given as an infusion into a vein over a period of time.
What do I do if my child misses a dose?
- Call your child’s doctor to find out what to do.
How do I store and/or throw out this drug?
- If you need to store this drug at home, talk with your child’s doctor, nurse, or pharmacist about how to store it.
General drug facts
- If your child’s symptoms or health problems do not get better or if they become worse, call your child’s doctor.
- Do not share your child’s drug with others and do not give anyone else’s drug to your child.
- Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
- Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.
- Some drugs may have another patient information leaflet. If you have any questions about this drug, please talk with your doctor, nurse, pharmacist, or other health care provider.
- If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
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