- It is used to treat ovarian cancer.
- It is used to treat breast cancer.
- If you have an allergy to this drug or any part of this drug.
- If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
- If you have had chemo treatments before and you still have blood problems from those treatments.
- If you take any other drugs (prescription or OTC, natural products, vitamins). There are many drugs that interact with this drug, like certain drugs that are used for HIV, infections, or seizures.
- If you are taking St. John’s wort. Do not take St. John’s wort with this drug. This drug may not work as well.
- If you are breast-feeding. Do not breast-feed while you take this drug or for 1 month after you stop this drug.
- Tell all of your health care providers that you take this drug. This includes your doctors, nurses, pharmacists, and dentists.
- If you have upset stomach, throwing up, loose stools (diarrhea), or are not hungry, talk with your doctor. There may be ways to lower these side effects.
- Have blood work checked as you have been told by the doctor. Talk with the doctor.
- Do not switch between different forms of this drug without first talking with the doctor.
- If you are 65 or older, use this drug with care. You could have more side effects.
- This drug is found in semen. Do not donate semen while you take this drug and for 3 months after your last dose.
- If you are a man and have sex with a female who could get pregnant, protect her from pregnancy during care and for 3 months after care ends. Use birth control that you can trust.
- If you are a man and your sex partner gets pregnant while you take this drug or within 3 months after your last dose, call your doctor right away.
- This drug may cause harm to the unborn baby or loss of the unborn baby if you take it while you are pregnant.
- If you are able to get pregnant, a pregnancy test will be done to show that you are NOT pregnant before starting this drug. Talk with your doctor.
- Use birth control that you can trust to prevent pregnancy while taking this drug and for 6 months after stopping this drug.
- If you get pregnant while taking this drug or within 6 months after your last dose, call your doctor right away.
- Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
- Signs of a urinary tract infection (UTI) like blood in the urine, burning or pain when passing urine, feeling the need to pass urine often or right away, fever, lower stomach pain, or pelvic pain.
- Swelling in the arms or legs.
- Very bad and sometimes deadly lung problems have happened with this drug. Call your doctor right away if you have lung or breathing problems like trouble breathing, shortness of breath, or a cough that is new or worse.
- Some people have had certain bone marrow problems while taking this drug. This includes a type of cancer called acute myeloid leukemia (AML). These problems may be deadly. These people all had other treatments with chemo or certain other drugs for their cancer before taking this drug. Call your doctor right away if you have blood in the urine or stools, fever, infections that happen often, shortness of breath, any bruising or bleeding, feel very tired or weak, or have weight loss.
- Back pain.
- Hard stools (constipation).
- Not hungry.
- Muscle or joint pain.
- Nose or throat irritation.
- Change in taste.
- Feeling tired or weak.
- Mouth irritation or mouth sores.
- Signs of a common cold.
- Flu-like signs.
- It is common to have diarrhea, upset stomach, throwing up, or stomach pain with this drug. Call your doctor if any of these side effects get very bad, bother you, or do not go away.
- Take with or without food.
- Swallow whole. Do not chew, break, or melt.
- Avoid Seville oranges.
- Avoid grapefruit and grapefruit juice.
- To gain the most benefit, do not miss doses.
- Keep taking this drug as you have been told by your doctor or other health care provider, even if you feel well.
- Do not open the capsules.
- Do not take the capsule if it is deformed or leaking.
- Skip the missed dose and go back to your normal time.
- Do not take 2 doses at the same time or extra doses.
- Store at room temperature.
- Store in a dry place. Do not store in a bathroom.
- Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
- Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.
- Avoid temperatures higher than 104 degrees F (40 degrees C). Do not take this drug if it has been at a temperature higher than 104 degrees F (40 degrees C).
- Store in original container.
- If your symptoms or health problems do not get better or if they become worse, call your doctor.
- Do not share your drugs with others and do not take anyone else’s drugs.
- Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
- Talk with the doctor before starting any new drug, including prescription or OTC, natural products, or vitamins.
- Some drugs may have another patient information leaflet. If you have any questions about this drug, please talk with your doctor, nurse, pharmacist, or other health care provider.
- If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.