Eloxatin; Oxaliplatin Injection; PMS-Oxaliplatin
- Very bad and sometimes deadly allergic side effects have rarely happened. Talk with your child’s doctor.
- Other drugs may be given before this drug to help avoid side effects.
- It is used to treat colon cancer.
- It is used to treat colorectal cancer.
- It may be given to your child for other reasons. Talk with the doctor.
- If your child has an allergy to this drug or any part of this drug.
- If your child is allergic to any drugs like this one or any other drugs, foods, or other substances. Tell the doctor about the allergy and what signs your child had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
- If your child has any of these health problems: Long QT on ECG, low magnesium levels, or low potassium levels.
If your child is breast-feeding a baby:
- Talk with the doctor if your child is breast-feeding a baby or plans to breast-feed a baby.
- Tell dentists, surgeons, and other doctors that your child is using this drug.
- Have your child avoid tasks or actions that call for alertness or clear eyesight until you see how this drug affects your child. These are things like riding a bike, playing sports, or using items such as scissors, lawnmowers, electric scooters, toy cars, or motorized vehicles.
- Have blood work checked as you have been told by the doctor. Talk with the doctor.
- Your child may bleed more easily. Make sure your child is careful and avoids injury. Be sure your child has a soft toothbrush.
- Your child may have more chance of getting an infection. Some infections have been deadly. Have your child wash hands often. Have your child stay away from people with infections, colds, or flu.
- Talk with the doctor before your child gets any vaccines. Use with this drug may either raise the chance of very bad infection or make the vaccine not work as well.
- If your child has an upset stomach or loose stools (diarrhea), is throwing up, or is not hungry, talk with the doctor. There may be ways to lower these side effects.
- Numbness, tingling, or burning of the feet or hands or around the mouth or throat may happen with this drug. Cold temperatures can make it worse. Have your child avoid cold food or drinks. Dress your child warmly and cover the skin if your child goes out in the cold. Have your child wear socks or gloves if your child has to touch cold objects like cold flooring or items in the refrigerator or freezer.
- Some people may have nerve problems that cause problems with daily living. Sometimes, this may lead to long-lasting or life-threatening problems. Call the doctor right away if your child has burning, numbness, or tingling that bothers your child or causes problems with daily living. Call the doctor right away if your child has problems walking, talking, swallowing, or saying words. Call the doctor right away if your child has eye pain, jaw tightness, a strange feeling in the tongue, or chest pressure.
- A very bad and sometimes deadly brain problem called posterior reversible encephalopathy syndrome (PRES) has happened with this drug. Talk with the doctor.
- This drug may cause a very bad and sometimes deadly heartbeat that is not normal (long QT on ECG, torsades de pointes). Sometimes, this has happened in people who are not at risk for these health problems. Talk with the doctor.
- A certain muscle problem (rhabdomyolysis) has happened with this drug. Rarely, this has led to organ problems and death. Call the doctor right away if your child has muscle pain or weakness.
If your child is or may be sexually active:
- Have your child use birth control to prevent pregnancy while taking this drug.
If your child is pregnant:
- This drug may cause harm to the unborn baby if your child takes it during pregnancy. If your child is pregnant or gets pregnant while taking this drug, call the doctor right away.
- Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
- Signs of infection like fever, chills, very bad sore throat, ear or sinus pain, cough, more sputum or change in color of sputum, pain with passing urine, mouth sores, or wound that will not heal.
- Signs of bleeding like throwing up blood or throw up that looks like coffee grounds; coughing up blood; blood in the urine; black, red, or tarry stools; bleeding from the gums; vaginal bleeding that is not normal; bruises without a reason or that get bigger; or any bleeding that is very bad or that you cannot stop.
- Signs of liver problems like dark urine, feeling tired, not hungry, upset stomach or stomach pain, light-colored stools, throwing up, or yellow skin or eyes.
- Signs of fluid and electrolyte problems like mood changes, confusion, muscle pain or weakness, a heartbeat that does not feel normal, very bad dizziness or passing out, fast heartbeat, more thirst, seizures, feeling very tired or weak, not hungry, unable to pass urine or change in the amount of urine produced, dry mouth, dry eyes, or very bad upset stomach or throwing up.
- Weakness on 1 side of the body, trouble speaking or thinking, change in balance, or blurred eyesight.
- Very loose stools (diarrhea).
- Change in eyesight.
- Loss of eyesight.
- Hearing loss.
- Chest pain.
- Sweating a lot.
- Feeling confused.
- Feeling less alert.
- Very bad headache.
- Very bad dizziness or passing out.
- A heartbeat that does not feel normal.
- A fast heartbeat.
- Very bad and sometimes deadly lung problems have happened with this drug. Call the doctor right away if your child has lung or breathing problems like trouble breathing, shortness of breath, or a cough that is new or worse.
- This drug may cause tissue damage if the drug leaks from the vein. Tell your child’s nurse if your child has any redness, burning, pain, swelling, blisters, skin sores, or leaking of fluid where the drug is going into your child’s body.
- Upset stomach or throwing up.
- Loose stools (diarrhea).
- Mouth irritation or mouth sores.
- Hard stools (constipation).
- Belly pain.
- Feeling tired or weak.
- Not hungry.
- Back pain.
- Not able to sleep.
- Change in taste.
- Hair loss.
- It is given as an infusion into a vein over a period of time.
- Call your child’s doctor to find out what to do.
- This drug will be given to your child in a hospital or doctor’s office. You will not store it at home.
- If your child’s symptoms or health problems do not get better or if they become worse, call your child’s doctor.
- Do not share your child’s drug with others and do not give anyone else’s drug to your child.
- Keep a list of all your child’s drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your child’s doctor.
- Talk with your child’s doctor before giving your child any new drug, including prescription or OTC, natural products, or vitamins.
- Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
- Check with your pharmacist about how to throw out unused drugs.
- Some drugs may have another patient information leaflet. If you have any questions about this drug, please talk with your child’s doctor, nurse, pharmacist, or other health care provider.
- If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
If you have any questions or concerns, talk with a member of your healthcare team. You can reach them Monday through Friday from 9:00 am to 5:00 pm at ____________________. After 5:00 pm, during the weekend, and on holidays, please call____________________. If there’s no number listed, or you’re not sure, call 212-639-2000.
Oxaliplatin©2016 Memorial Sloan Kettering Cancer Center - Generated on April 26, 2016