This information from Lexicomp® explains what you need to know about this medication, including what it’s used for, how to take it, its side effects, and when to call your healthcare provider.
Zeposia 7-Day Starter Pack; Zeposia Starter Kit
- It is used to treat MS (multiple sclerosis).
- If you are allergic to this drug; any part of this drug; or any other drugs, foods, or substances. Tell your doctor about the allergy and what signs you had.
- If you have ever had any of these health problems: Certain types of abnormal heartbeats (heart block, sick sinus syndrome, long QT on ECG), chest pain (angina), heart attack, heart failure, transient ischemic attack (TIA), or stroke.
- If you have liver disease.
- If you have sleep apnea.
- If you have had a vaccine in the past month.
- If you are taking or have recently taken any drugs that can cause a slow heartbeat, a certain type of abnormal heartbeat (prolonged QT interval), or suppress your immune system. There are many drugs that can do this. Ask your doctor or pharmacist if you are not sure.
- If you have taken certain drugs for depression or Parkinson’s disease in the last 14 days. This includes isocarboxazid, phenelzine, tranylcypromine, selegiline, or rasagiline. Very high blood pressure may happen.
- If you take any drugs (prescription or OTC, natural products, vitamins) that must not be taken with this drug, like certain drugs that are used for infections, MS (multiple sclerosis), or drugs that affect the immune system. There are many drugs that must not be taken with this drug.
- If you have taken alemtuzumab.
This is not a list of all drugs or health problems that interact with this drug.
Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take this drug with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.
- Tell all of your health care providers that you take this drug. This includes your doctors, nurses, pharmacists, and dentists.
- Have blood work checked as you have been told by the doctor. Talk with the doctor.
- You may have more chance of getting an infection while taking this drug and for 3 months after stopping it. Some infections have been severe. Rarely, this has been deadly. Wash hands often. Stay away from people with infections, colds, or flu.
- Talk with your doctor before getting any vaccines while taking this drug and for 3 months after stopping it. Use with this drug may either raise the chance of an infection or make the vaccine not work as well.
- If you have not had chickenpox or a chickenpox vaccine, talk with your doctor.
- Slow or abnormal heartbeat may happen with this drug, especially after your first dose. People with certain heart problems will need to be watched closely for 6 hours after the first dose of this drug. Before starting this drug, tell your doctor about all of your other drugs and health problems. Call your doctor right away if you have dizziness, slow heartbeat or a heartbeat that does not feel normal, or tiredness.
- You will need an ECG before starting this drug.
- High blood pressure has happened with this drug. Have your blood pressure checked as you have been told by your doctor.
- Too much of some foods and drinks, like some cheeses and red wine, may cause sudden, severe high blood pressure when you are taking this drug. Talk with your doctor about your risk for this effect. Get a list of foods and drinks that can cause this effect. Limit these foods and drinks as your doctor has told you.
- When this drug is stopped, MS signs can come back and may be worse than before or during treatment. If you stop this drug and your MS signs get worse, call your doctor right away.
- Do not stop taking this drug without calling the doctor who ordered it for you.
- Cases of cancer have happened in some people taking this drug. If you have questions, talk with the doctor.
- This drug may cause harm to the unborn baby if you take it while you are pregnant.
- Women must use birth control while taking this drug and for some time after the last dose. Ask your doctor how long to use birth control. If you get pregnant, call your doctor right away.
- Tell your doctor if you are breast-feeding. You will need to talk about any risks to your baby.
WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:
- Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
- Signs of infection like fever, chills, very bad sore throat, ear or sinus pain, cough, more sputum or change in color of sputum, pain with passing urine, mouth sores, or wound that will not heal.
- Signs of meningitis like headache with fever, stiff neck, upset stomach, confusion, or if lights bother the eyes.
- Signs of liver problems like dark urine, feeling tired, not hungry, upset stomach or stomach pain, light-colored stools, throwing up, or yellow skin or eyes.
- Signs of high or low blood pressure like very bad headache or dizziness, passing out, or change in eyesight.
- Chest pain or pressure.
- Shortness of breath.
- Trouble breathing that is new or worse.
- Change in eyesight.
- Passing urine more often.
- A very bad and sometimes deadly brain problem called posterior reversible encephalopathy syndrome (PRES) has happened with this drug. Call your doctor right away if you have signs like feeling confused, lowered alertness, change in eyesight, loss of eyesight, seizures, or very bad headache.
- A very bad brain problem called progressive multifocal leukoencephalopathy (PML) may happen with this drug. It may cause disability or can be deadly. Tell your doctor right away if you have signs like confusion, memory problems, low mood (depression), change in the way you act, change in strength on 1 side is greater than the other, trouble speaking or thinking, change in balance, or change in eyesight.
All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:
- Signs of a common cold.
- Back pain.
These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.
You may report side effects to your national health agency.
Use this drug as ordered by your doctor. Read all information given to you. Follow all instructions closely.
- Swallow whole. Do not chew, open, or crush.
- Take with or without food.
- It is important that you do not miss or skip a dose of this drug during treatment.
- If you miss 1 day of this drug within the first 2 weeks of taking it, call your doctor to find out how to restart.
- If you miss a dose of this drug after the first 2 weeks of taking it, skip the missed dose and go back to your normal time.
- Do not take 2 doses at the same time or extra doses.
- Store at room temperature in a dry place. Do not store in a bathroom.
- Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
- Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.
- If your symptoms or health problems do not get better or if they become worse, call your doctor.
- Do not share your drugs with others and do not take anyone else’s drugs.
- Some drugs may have another patient information leaflet. If you have any questions about this drug, please talk with your doctor, nurse, pharmacist, or other health care provider.
- This drug comes with an extra patient fact sheet called a Medication Guide. Read it with care. Read it again each time this drug is refilled. If you have any questions about this drug, please talk with the doctor, pharmacist, or other health care provider.
- If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
This information should not be used to decide whether or not to take this medicine or any other medicine. Only the healthcare provider has the knowledge and training to decide which medicines are right for a specific patient. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from the healthcare provider. You must talk with the healthcare provider for complete information about the risks and benefits of using this medicine.
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