- This drug may cause very bad nervous system problems including great sleepiness, seizures, weakness, or numbness or tingling of the feet or hands. Talk with the doctor.
- This drug may cause kidney problems in some patients. Talk with the doctor.
- This drug may cause liver problems in some patients. Talk with the doctor.
- This drug may cause lung problems. Closely read the part in this leaflet which lists when to call your child’s doctor.
- Some people using this drug with fludarabine had very bad or deadly lung problems. Do not give this drug to your child if your child is also being treated with fludarabine.
- It is used to treat leukemia.
- It may be given to your child for other reasons. Talk with the doctor.
- If your child has an allergy to this drug or any part of this drug.
- If your child is allergic to any drugs like this one or any other drugs, foods, or other substances. Tell the doctor about the allergy and what signs your child had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
- Tell dentists, surgeons, and other doctors that your child is using this drug.
- Your child may have more chance of getting infections. Avoid crowds and people with infections, colds, or flu.
- Your child may bleed more easily. Make sure your child is careful and avoids injury. Be sure your child has a soft toothbrush.
- If your child has an infection before starting this drug it may get worse and sometimes lead to death. Talk with the doctor.
- Very bad and sometimes deadly lung problems and low blood pressure have happened when this drug was used with other drugs like carmustine, cyclophosphamide, and etoposide. Talk with your doctor.
- Have your child’s blood work checked often. Talk with your child’s doctor.
- Talk with the doctor before your child gets any vaccines. Use with this drug may either raise the chance of very bad infection or make the vaccine not work as well.
If your child is or may be sexually active:
- Have your child use birth control to prevent pregnancy while taking this drug.
If your child is pregnant or breast-feeding a baby:
- This drug may cause harm to the unborn baby if your child takes it during pregnancy.
- Talk with the doctor if your child is pregnant, becomes pregnant, or is breast-feeding a baby. You will need to talk about the benefits and risks of using this drug.
- Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
- Signs of infection like fever, chills, very bad sore throat, ear or sinus pain, cough, more sputum or change in color of sputum, pain with passing urine, mouth sores, or wound that will not heal.
- Signs of liver problems like dark urine, feeling tired, not hungry, upset stomach or stomach pain, light-colored stools, throwing up, or yellow skin or eyes.
- Signs of kidney problems like unable to pass urine, change in how much urine is passed, blood in the urine, or a big weight gain.
- Shortness of breath.
- Chest pain or pressure or a fast heartbeat.
- Change in thinking clearly and with logic.
- Low mood (depression).
- Feeling nervous and excitable.
- Very bad dizziness or passing out.
- Any bruising or bleeding that is not normal.
- Feeling very tired or weak.
- Swelling in the arms or legs.
- Upset stomach or throwing up.
- Feeling tired or weak.
- Loose stools (diarrhea).
- Belly pain.
- Not hungry.
- Runny nose.
- Mouth irritation or mouth sores.
- Muscle or joint pain.
- Sweating a lot.
- It is given as a shot into a vein over a period of time.
- Call the doctor to find out what to do.
- This drug will be given to your child in a hospital or doctor’s office. You will not store it at home.
- If your child’s symptoms or health problems do not get better or if they become worse, call your child’s doctor.
- Do not share your child’s drug with others and do not give anyone else’s drug to your child.
- Keep a list of all your child’s drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your child’s doctor.
- Talk with your child’s doctor before giving your child any new drug, including prescription or OTC, natural products, or vitamins.
- Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
- Check with your pharmacist about how to throw out unused drugs.
- Some drugs may have another patient information leaflet. If you have any questions about this drug, please talk with your child’s doctor, nurse, pharmacist, or other health care provider.
- If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
If you have any questions or concerns, talk with a member of your healthcare team. You can reach them Monday through Friday from 9:00 am to 5:00 pm at ____________________. After 5:00 pm, during the weekend, and on holidays, please call____________________. If there’s no number listed, or you’re not sure, call 212-639-2000.
Pentostatin©2016 Memorial Sloan Kettering Cancer Center - Generated on February 12, 2016