Xarelto; Xarelto Starter Pack
- People who have any type of spinal or epidural procedure are more likely to have bleeding problems around the spine when already on this drug. This bleeding rarely happens, but can lead to not being able to move body (paralysis) long-term or paralysis that will not go away. The risk is raised in people who have problems with their spine, a certain type of epidural catheter, or have had spinal surgery. The risk is also raised in people who take any other drugs that may affect how the blood clots like blood-thinner drugs (like warfarin), aspirin, or nonsteroidal anti-inflammatory drugs (NSAIDs). Talk with the doctor.
- Tell your doctor you use this drug before you have a spinal or epidural procedure. Call your doctor right away if you have any signs of nerve problems like back pain, numbness or tingling, muscle weakness, paralysis, or loss of bladder or bowel control.
- Talk with your doctor if you have recently had or will be having a spinal or epidural procedure. Some time may need to pass between the use of this drug and your procedure. Talk with your doctor.
- Stopping this drug before you are supposed to may raise the chance of blood clots. Do not stop taking this drug without talking to your doctor.
- It is used to thin the blood so that clots will not form.
- It is used to treat blood clots.
- If you have an allergy to rivaroxaban or any other part of this drug.
- If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
- If you have bleeding problems.
- If you have any of these health problems: Kidney disease or liver disease.
- If you have had a heart valve replaced.
- If you are taking any of these drugs: Carbamazepine, conivaptan, indinavir, itraconazole, ketoconazole, lopinavir, phenobarbital, phenytoin, rifampin, ritonavir, or St. John’s wort.
- If you are breast-feeding or plan to breast-feed.
- Tell all of your health care providers that you take this drug. This includes your doctors, nurses, pharmacists, and dentists.
- You may bleed more easily. Be careful and avoid injury. Use a soft toothbrush and an electric razor.
- Very bad and sometimes deadly bleeding problems have happened with this drug. Talk with the doctor.
- Have blood work checked as you have been told by the doctor. Talk with the doctor.
- If you are 65 or older, use this drug with care. You could have more side effects.
- Tell your doctor if you are pregnant or plan on getting pregnant. You will need to talk about the benefits and risks of using this drug while you are pregnant.
- Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
- Signs of bleeding like throwing up blood or throw up that looks like coffee grounds; coughing up blood; blood in the urine; black, red, or tarry stools; bleeding from the gums; vaginal bleeding that is not normal; bruises without a reason or that get bigger; or any bleeding that is very bad or that you cannot stop.
- Very bad dizziness or passing out.
- A burning, numbness, or tingling feeling that is not normal.
- Muscle weakness.
- A fall or crash when you hit your head. Talk with your doctor even if you feel fine.
- Feeling confused.
- Very bad headache.
- Feeling very tired or weak.
- Pain, swelling, or new drainage at wound sites.
- Take with a full glass of water.
- If you cannot swallow tablets, the tablet may be crushed and mixed with applesauce. Take within 4 hours of mixing.
- To gain the most benefit, do not miss doses.
- Keep taking this drug as you have been told by your doctor or other health care provider, even if you feel well.
10 mg tablet:
- Take with or without food.
- Those who have feeding tubes may also use the 10 mg tablets. Crush tablets and mix with 10 teaspoons (50 mL) of water. Give within 4 hours of mixing.
15 mg and 20 mg tablets:
- Take this drug with food.
- Those who have feeding tubes may also use the 15 mg or 20 mg tablets. Crush tablets and mix with 50 mL of water. Give within 4 hours of mixing. Give enteral feeding right after giving dose.
15 mg twice daily dosing:
- Take missed dose right away to make sure you get 30 mg in one day. You may take 2 tablets at the same time. Then go back to your normal times the next day.
All other dosing:
- Take a missed dose as soon as you think about it.
- If it is close to the time for your next dose, skip the missed dose and go back to your normal time.
- Do not take 2 doses at the same time or extra doses.
- Store at room temperature.
- Store in a dry place. Do not store in a bathroom.
- Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
- Check with your pharmacist about how to throw out unused drugs.
- If your symptoms or health problems do not get better or if they become worse, call your doctor.
- Do not share your drugs with others and do not take anyone else’s drugs.
- Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
- Talk with the doctor before starting any new drug, including prescription or OTC, natural products, or vitamins.
- Some drugs may have another patient information leaflet. If you have any questions about this drug, please talk with your doctor, nurse, pharmacist, or other health care provider.
- If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.