In the News

Learn whether eating soy products causes cancer.

Scientists are looking to exploit defects in DNA repair as an Achilles’ heel in cancer.

Get the latest research updates from investigators across MSK on why so many young adults are getting cancers.

Analysis of long-preserved single cells on pathology slides aims to provide new clues about the genes that make breast cancer more aggressive.

Radiation therapy after surgery can sharply reduce the chance that certain low-risk breast cancers will return.

Researchers find an epigenetic role in how breast cancer tumors develop resistance to treatment.

Read about a few of the MSK studies being presented at the 2019 American Society of Clinical Oncology's annual meeting.

Even the most common cancers have aspects that are not fully grasped by the public.

A new finding provides insight into how breast cancer develops resistance to aromatase inhibitors.

Researchers at Memorial Sloan Kettering Cancer Center have identified, for the first time, an epigenetic mechanism promoting breast cancer. The team found that inhibition of the PI3K pathway leads to activation of ER-dependent transcription through the epigenetic regulator KMT2D. These findings provide a rationale for epigenetic therapy in patients with PIK3CA-mutant, ER-positive breast cancer. While epigenetic factors have been known to play an important role in various cancers such as leukemia and lymphoma, this is the first evidence found in breast cancer. This research co-led by José Baselga, MD, PhD, Physician-in-Chief and Chief Medical Officer, appears in the March 24, 2017 issue of Science. For more information on this work and to speak with the study authors, contact [email protected].