Desmoplastic Small Round Cell Tumors (DSRCT) Treatment

Treating desmoplastic small round cell tumors (DSRCTs) usually starts with chemotherapy to shrink the tumor and prevent new ones from forming. Then we perform surgery to remove the cancerous areas. Our surgeons are leaders in procedures that not only completely remove tumors but also make sure patients can use the affected body part as freely as possible.

For tumors that respond well to radiation, our radiation oncologists use a treatment called intensity-modulated radiation therapy. This precisely targets tumors, leaving healthy tissue unharmed, even when the cancer is near a vital organ.

Depending on the tumor’s size, we offer some patients the option to take part in a clinical trial that sends high doses of radiation to tumor cells without harming nearby healthy cells. This treatment, called radioimmunotherapy, uses a molecule called an antibody to bring radiation precisely to cancer cells. Since DSRCT usually begins in the abdomen and pelvis, we often start this treatment in the lower torso.

We are very proud of our expertise in caring for young people with DSRCTs and other rare cancers. Our pediatrics team is hopeful that further research will improve outcomes and set new standards of care for patients everywhere.