This information describes the common uses of AHCC, how it works, and its possible side effects.
Active Hexose Correlated Compound
How It Works
AHCC appears to have immunomodulatory and anticancer effects, but large human studies are lacking.
Active hexose correlated compound (AHCC) is an extract of mushrooms from the Basidiomycete class, including shiitake mushrooms. This product contains polysaccharides called glucans, which scientists think are responsible for its biological activity.
Lab studies suggest AHCC may enhance the activity of some types of immune cells. Animal studies suggest that AHCC has antioxidant and anti-inflammatory effects, and may improve immune system response in mice with chemotherapy-weakened immune systems. In a few human studies, AHCC improved liver function in patients with hepatocellular carcinoma and cirrhosis, and reduced blood levels of some tumor markers.
To prevent and treat cancer
Laboratory experiments suggest anticancer activity. A clinical study supported the use of AHCC in patients undergoing surgical resection of hepatocellular carcinoma, but another study found it ineffective for early stage prostate cancer. More research is needed.
Do Not Take If
You are taking drugs that are substrates of Cytochrome P450 2D6: Lab studies suggest AHCC may make these drugs less effective. Clinical significance is not known.
Diarrhea and itching have been reported in patients following consumption of AHCC.
If you have any questions or concerns, contact a member of your healthcare team directly or call 212-639-2000 for help.
If you have any questions, contact a member of your healthcare team. After 5:00 pm, during the weekend, and on holidays, call 212-639-2000.