Jennifer Sims, PhD

Assistant Member, Human Oncology & Pathogenesis Program

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Jennifer Sims, PhD

Assistant Member, Human Oncology & Pathogenesis Program

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Jennifer Sims, PhD

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[email protected]

Education

PhD, Microbiology and Molecular Genetics (2009), Harvard University, Cambridge, MA; BS, Molecular Biology; BA, Literature/Writing (2004), University of California - San Diego, La Jolla, CA

Research Interests

Using next-generation sequencing technology to study the determinants of efficacy in the adaptive immune response to cancer.     

Publications

Sims, J.S., Grinshpun, B., Feng, Y., Ung, T.H., Neira, J.A., Samanamud, J.L., Canoll, P., Shen, Y., Sims, P.A. and Bruce, J.N., 2016. Diversity and divergence of the glioma-infiltrating T-cell receptor repertoire. Proceedings of the National Academy of Sciences, 113(25), pp.E3529-E3537. 

Gonzalez, C., Sims, J.S., Hornstein, N., Mela, A., Garcia, F., Lei, L., Gass, D.A., Amendolara, B., Bruce, J.N., Canoll, P. and Sims, P.A., 2014. Ribosome profiling reveals a cell-type-specific translational landscape in brain tumors. Journal of Neuroscience, 34(33), pp.10924-10936.

Feeley, E.M., Sims, J.S., John, S.P., Chin, C.R., Pertel, T., Chen, L.M., Gaiha, G.D., Ryan, B.J., Donis, R.O., Elledge, S.J. and Brass, A.L., 2011. IFITM3 inhibits influenza A virus infection by preventing cytosolic entry. PLoS Pathog, 7(10), p.e1002337. 

Sims, J.S., Militello, K.T., Sims, P.A., Patel, V.P., Kasper, J.M. and Wirth, D.F., 2009. Patterns of gene-specific and total transcriptional activity during the Plasmodium falciparum intraerythrocytic developmental cycle. Eukaryotic cell, 8(3), pp.327-338.