Karen Hunter Cohn, PhD

Vice President, Translational Science at Celmatix, New York, NY

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Pictured: Karen Hunter Cohn

Office Phone

646-888-2046

Office Fax

646-422-0231

Lab Phone

646-888-2059

Email

hunterk@sloankettering.edu

Dissertation

Investigation of Tumor Cell Intrinsic and Extrinsic Regulators of Pancreatic Neuroendocrine Tumorigenesis (2013)

Mentor

Johanna Joyce, PhD

Start Year

2007

End Year

2013

Education

Massachusetts Institute of Technology

Publications

Akkari L, Gocheva V, Kester JC, Hunter KE, Quick ML, Sevenich L, Wang HW, Peters C, Tang LH, Klimstra DS, Reinheckel T, Joyce JA. (2014) Distinct functions of macrophage-derived and cancer cell-derived cathepsin Z combine to promote tumor malignancy via interactions with the extracellular matrix. Genes Dev., 28, 2134-50. PMCID: PMC4180975.

Hunter K, Palermo C, Kester J, Simpson K, Li J, Tang L, Klimstra D, Vlodavsky I, Joyce J. (2014) Heparanase promotes lymphangiogenesis and tumor invasion in pancreatic neuroendocrine tumors. Oncogene, 3, 1799-1808.

Hunter K, Quick M, Sadanandam A, Hanahan D, Joyce J. (2013) Identification and characterization of poorly differentiated invasive carcinomas in a mouse model of pancreatic neuroendocrine tumorigenesis. PLoS One, 8, 1-11.

Pyonteck S, Gadea B, Wang H, Gocheva V, Hunter K, Tang L, Joyce J. (2012) Deficiency of the macrophage growth factor CSF-1 disrupts pancreatic neuroendocrine tumor development. Oncogene, 31, 1459-1467.

Gocheva V, Wang H, Gadea B, Shree T, Hunter K, Garfall A, Berman T, Joyce J. (2010) IL-4 induces cathepsin protease activity in tumor-associated macrophages to promote cancer growth and invasion. Genes Dev, 24, 241-255.

Williams BR, Prabhu VR, Hunter KE, Glazier CM, Whittaker CA, Housman DE, Amon A. (2008) Aneuploidy affects proliferation and spontaneous immortalization in mammalian cells. Science. 322, 703-9. PMCID: PMC2701511