Publications

Gao C, Xiao G, Piersigilli A, Gou J, Ogunwobi O, Bargonetti J. Context-dependent roles of MDMX (MDM4) and MDM2 in breast cancer proliferation and circulating tumor cells. Breast Cancer Res. 2019 Jan 14;21(1):5. doi: 10.1186/s13058-018-1094-8.

Cheleuitte-Nieves C. Enrichment and outcomes in female mice. Lab Animal. 2019 Jan 14. 48:53–54.

Cheleuitte-Nieves C, Gulvik CA, McQuiston JR, Humrighouse BW, Bell ME, Villarma A, Fischetti VA, Westblade LF, Lipman NS. Genotypic differences between strains of the opportunistic pathogen Corynebacterium bovis isolated from humans, cows, and rodents. PLoS One. 2018 Dec 26;13(12):e0209231.

Cheal SM, Xu H, Guo HF, Patel M, Punzalan B, Fung EK, Lee SG, Bell M, Singh M, Jungbluth AA, Zanzonico PB, Piersigilli A, Larson SM, Cheung NV. Theranostic pretargeted radioimmunotherapy of internalizing solid tumor antigens in human tumor xenografts in mice: Curative treatment of HER2-positive breast carcinoma. Theranostics. 2018 Oct 6;8(18):5106-5125.

Gabrielson K, Maronpot R, Monette S, Mlynarczyk C, Ramot Y, Nyska A, Sysa-Shah P. In Vivo Imaging With Confirmation by Histopathology for Increased Rigor and Reproducibility in Translational Research: A Review of Examples, Options, and Resources. ILAR journal. 2018; 2018 Dec 12. [Epub ahead of print].

Farber G, Parks MM, Lustgarten Guahmich N, Zhang Y, Monette S, Blanchard SC, Di Lorenzo A, Blobel CP. ADAM10 controls the differentiation of the coronary arterial endothelium. Angiogenesis. 2018; 2018 Nov 16. [Epub ahead of print].

An Atypical Parvovirus Drives Chronic Tubulointerstitial Nephropathy and Kidney Fibrosis. Roediger B, Lee Q, Tikoo S, Cobbin JCA, Henderson JM, Jormakka M, O’Rourke MB, Padula MP, Pinello N, Henry M, Wynne M, Santagostino SF, Brayton CF, Rasmussen L, Lisowski L, Tay SS, Harris DC, Bertram JF, Dowling JP, Bertolino P, Lai JH, Wu W, Bachovchin WW, Wong JJ, Gorrell MD, Shaban B, Holmes EC, Jolly CJ, Monette S, Weninger W. Cell. 2018; 175(2):530-543.e24.

Giavridis T, van der Stegen SJC, Eyquem J, Hamieh M, Piersigilli A, Sadelain M. CAR T cell-induced cytokine release syndrome is mediated by macrophages and abated by IL-1 blockade. Nat Med. 2018 Jun;24(6):731-738. doi: 10.1038/s41591-018-0041-7. Epub 2018 May 28.

Haxaire C, Hakobyan N, Pannellini T, Carballo C, McIlwain D, Mak TW, Rodeo S, Acharya S, Li D, Szymonifka J, Song X, Monette S, Srivastava A, Salmon JE, Blobel CP. Blood-induced bone loss in murine hemophilic arthropathy is prevented by blocking the iRhom2/ADAM17/TNFα pathway. Blood. 2018; PubMed

Lee SC, North K, Kim E, Jang E, Obeng E, Lu SX, Liu B, Inoue D, Yoshimi A, Ki M, Yeo M, Zhang XJ, Kim MK, Cho H, Chung YR, Taylor J, Durham BH, Kim YJ, Pastore A, Monette S, Palacino J, Seiler M, Buonamici S, Smith PG, Ebert BL, Bradley RK, Abdel-Wahab O. Synthetic Lethal and Convergent Biological Effects of Cancer-Associated Spliceosomal Gene Mutations. Cancer cell. 2018; 34(2):225-241.e8. PubMed

Kodama H, Ueshima E, Gao S, Monette S, Paluch LR, Howk K, Erinjeri JP, Solomon SB, Srimathveeravalli G. High power microwave ablation of normal swine lung: impact of duration of energy delivery on adverse event and heat sink effects. International journal of hyperthermia: the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group. 2018; :1-8. PubMed

Moore AR, Ran L, Guan Y, Sher JJ, Hitchman TD, Zhang JQ, Hwang C, Walzak EG, Shoushtari AN, Monette S, Murali R, Wiesner T, Griewank KG, Chi P, Chen Y. GNA11 Q209L Mouse Model Reveals RasGRP3 as an Essential Signaling Node in Uveal Melanoma. Cell reports. 2018; 22(9):2455-2468. NIHMSID: NIHMS949230. PMCID: PMC5854482. PubMed 

Kim K, Watson PA, Lebdai S, Jebiwott S, Somma AJ, La Rosa S, Mehta D, Murray KS, Lilja H, Ulmert D, Monette S, Scherz A, Coleman JA. Androgen Deprivation Therapy Potentiates the Efficacy of Vascular Targeted Photodynamic Therapy of Prostate Cancer Xenografts. Clinical cancer research: an official journal of the American Association for Cancer Research. 2018; 24(10):2408-2416. NIHMSID: NIHMS945372 PMCID: PMC5955858. PubMed

Ueshima E, Schattner M, Mendelsohn R, Gerdes H, Monette S, Takaki H, Durack JC, Solomon SB, Srimathveeravalli G. Transmural ablation of the normal porcine common bile duct with catheter-directed irreversible electroporation is feasible and does not affect duct patency. Gastrointestinal endoscopy. 2018; 87(1):300.e1-300.e6. NIHMSID: NIHMS875417  PMCID: PMC5681441. PubMed

Cheleuitte-Nieves C, Gulvik C, Humrighouse B, Bell M, Villarma A, Westblade L, Lipman N, Fischetti V & McQuiston J. 2018. Draft Reference Genome of Corynebacterium mastitidis 16-1433 Isolated from a Mouse. Genome Announcements. 6(7):e00050-18.

Peneyra SM, Cardona-Costa J, White J, Whipps CM, Riedel ER, Lipman NS, Lieggi C. Zebrafish. Transmission of Pseudoloma neurophilia in Laboratory Zebrafish (Danio rerio) When Using Mass Spawning Chambers and Recommendations for Chamber Disinfection. Zebrafish. 2018 Feb; 15(1): 63-72.

Farber G, Hurtado R, Loh S, Monette S, Mtui J, Kopan R, Quaggin S, Meyer-Schwesinger C, Herzlinger D, Scott RP, Blobel CP. Glomerular endothelial cell maturation depends on ADAM10, a key regulator of Notch signaling. Angiogenesis. 2018 Feb 3. doi: 10.1007/s10456-018-9599-4. PubMed

O’Shaughnessy MJ, Murray KS, La Rosa SP, Budhu S, Merghoub T, Somma A, Monette S, Kim K, Corradi RB, Scherz A, Coleman JA. Systemic Antitumor Immunity by PD-1/PD-L1 Inhibition Is Potentiated by Vascular-Targeted Photodynamic Therapy of Primary Tumors. Clin Cancer Res. 2018 Feb 1;24(3):592-599. doi: 10.1158/1078-0432.CCR-17-0186. PubMed

Sharma SK, Chow A, Monette S, Vivier D, Pourat J, Edwards KJ, Dilling TR, Abdel-Atti D, Zeglis BM, Poirier JT, Lewis JS. Fc-mediated Anomalous Biodistribution of Therapeutic Antibodies in Immunodeficient Mouse Models. Cancer Res. 2018 Jan 23. pii: canres.1958.2017. doi: 10.1158/0008-5472.CAN-17-1958. PubMed

Rosenberg JB, Kaplitt M, De BP, Chen A, Flagiello T, Salami CO, Pey E, Zhao L, Ricart Arbona R, Monette S, Dyke J, Ballon D, Kaminsky SM, Sondhi D, Petsko G, Paul S, Crystal RG. AAVrh.10-mediated APOE2 CNS Gene Therapy for APOE4-associated Alzheimer’s Disease. Hum Gene Ther Clin Dev. 2018 Feb 6. doi: 10.1089/humc.2017.231. PubMed

Sharma SK, Pourat J, Abdel-Atti D, Carlin SD, Piersigilli A, Bankovich AJ, Gardner EE, Hamdy O, Isse K, Bheddah S, Sandoval J, Cunanan KM, Johansen EB, Allaj V, Sisodiya V, Liu D, Zeglis BM, Rudin CM, Dylla SJ, Poirier JT, Lewis JS. Noninvasive Interrogation of DLL3 Expression in Metastatic Small Cell Lung Cancer. Cancer Res. 2017 Jul 15;77(14):3931-3941.

Lee KS, Santagostino SF, Li D, Ramjit A, Serrano K, Ginsberg MD, Ding BS, Rafii S, Madoff DC. Catheter-directed Intraportal Delivery of Endothelial Cell Therapy for Liver Regeneration: A Feasibility Study in a Large-Animal Model of Cirrhosis. Radiology. 2017 Oct;285(1):114-123. doi: 10.1148/radiol.2017162617. Epub 2017 May 11.

Nargund AM, Pham CG, Dong Y, Wang PI, Osmangeyoglu HU, Xie Y, Aras O, Han S, Oyama T, Takeda S, Ray CE, Dong Z, Berge M, Hakimi AA, Monette S, Lekaye CL, Koutcher JA, Leslie CS, Creighton CJ, Weinhold N, Lee W, Tickoo SK, Wang Z, Cheng EH, Hsieh JJ. The SWI/SNF Protein PBRM1 Restrains VHL-Loss-Driven Clear Cell Renal Cell Carcinoma. Cell reports. 2017; 18(12):2893-2906. NIHMSID: NIHMS856904 PMCID: PMC5431084. PubMed

Fischer JC, Bscheider M, Eisenkolb G, Lin CC, Wintges A, Otten V, Lindemans CA, Heidegger S, Rudelius M, Monette S, Porosnicu Rodriguez KA, Calafiore M, Liebermann S, Liu C, Lienenklaus S, Weiss S, Kalinke U, Ruland J, Peschel C, Shono Y, Docampo M, Velardi E, Jenq RR, Hanash AM, Dudakov JA, Haas T, van den Brink MRM, Poeck H. RIG-I/MAVS and STING signaling promote gut integrity during irradiation- and immune-mediated tissue injury. Science translational medicine.
2017; 9(386). NIHMSID: NIHMS896799 PMCID: PMC5604790. PubMed

Srimathveeravalli G, Cornelis F, Wimmer T, Monette S, Kimm SY, Maybody M, Solomon SB, Coleman JA, Durack JC. Normal Porcine Ureter Retains Lumen Wall Integrity but Not Patency Following Catheter-Directed Irreversible Electroporation: Imaging and Histologic Assessment over 28 Days. Journal of vascular and interventional radiology : JVIR. 2017; 28(6):913-919.e1. NIHMSID: NIHMS858022  PMCID: PMC5441958. PubMed

Santagostino SF, Arbona RJR, Nashat MA, White JR, Monette S. Pathology of Aging in NOD scid gamma Female Mice. Veterinary pathology. 2017; 54(5):855-869. NIHMSID: NIHMS866771 PMCID: PMC5548647. PubMed

Braden GC, Rasmussen S, Monette S, Tolwani RJ. Effects of Breeding Configuration on Maternal and Weanling Behavior in Laboratory Mice. Journal of the American Association for Laboratory Animal Science: JAALAS. 2017; 56(4):369-376. PMCID: PMC5517325. PubMed

Alidori S, Thorek DLJ, Beattie BJ, Ulmert D, Almeida BA, Monette S, Scheinberg DA, McDevitt MR. Carbon nanotubes exhibit fibrillar pharmacology in primates. PloS one. 2017; 12(8):e0183902. PMCID: PMC5573305. PubMed

Cheal SM, Fung EK, Patel M, Xu H, Guo HF, Zanzonico PB, Monette S, Wittrup KD, Cheung NV, Larson SM. Curative Multicycle Radioimmunotherapy Monitored by Quantitative SPECT/CT-Based Theranostics, Using Bispecific Antibody Pretargeting Strategy in Colorectal Cancer. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2017; 58(11):1735-1742. PMCID: PMC5666642. PubMed

Kaye EA, Maybody M, Monette S, Solomon SB, Gulati A. Ablation of the sacroiliac joint using MR-guided high intensity focused ultrasound: a preliminary experiment in a swine model. Journal of therapeutic ultrasound. 2017; 5:17. PMCID: PMC5483839. PubMed

Cheleuitte-Nieves C, Euler C, Lipman NS, Fischetti VA. 2017. Exploring novel antimicrobial therapies. Laboratory Animal Science Professional. September Ed. 27-28.

Kodama H, Vroomen LG, Ueshima E, Reilly J, Brandt W, Paluch LR, Monette S, Jones D, Solomon SB, Srimathveeravalli G. Catheter-based endobronchial electroporation is feasible for the focal treatment of peribronchial tumors. J Thorac Cardiovasc Surg. 2017 Dec 20. pii: S0022-5223(17)33003-9. doi: 10.1016/j.jtcvs.2017.11.097. PubMed

Grunert, P., Moriguchi, Y., Grossbard, B.P., Ricart Arbona, R.J., Bonassar, L.J., Härtl, R. Degenerative changes of the canine cervical spine after discectomy procedures, an in vivo study. BMC Vet Res. 2017 Jun 23;13(1):193.

Gerwin P.M., Ricart Arbona R.J., Riedel E.R., Lepherd M., Henderson K.S., Lipman N.S. Evaluation of Traditional and Contemporary Methods for Detecting Syphacia obvelata and Aspiculuris tetraptera in Laboratory Mice. J Am Assoc Lab Anim Sci. 2017 Jan; 56(1): 32–41.

Li X, Maretzky T, Perez-Aguilar JM, Monette S, Weskamp G, Le Gall S, Beutler B, Weinstein H, Blobel CP. Structural modeling defines transmembrane residues in ADAM17 that are crucial for Rhbdf2-ADAM17-dependent proteolysis. J Cell Sci. 2017;130(5):868-78. doi: 10.1242/jcs.196436. PubMed

Moriguchi Y, Mojica-Santiago J, Grunert P, Pennicooke B, Berlin C, Khair T, Navarro-Ramirez R, Ricart Arbona RJ, Nguyen J, Härtl R, Bonassar LJ. Total disc replacement using tissue-engineered intervertebral discs in the canine cervical spine. PLoS One. 2017 Oct 20;12(10):e0185716.

Li MM, Bozzacco L, Hoffmann HH, Breton G, Loschko J, Xiao JW, Monette S, Rice CM, MacDonald MR. Interferon regulatory factor 2 protects mice from lethal viral neuroinvasion. The Journal of experimental medicine. 2016; 213(13):2931-2947. PMCID: PMC5154937. PubMed

Kim SE, Zhang L, Ma K, Riegman M, Chen F, Ingold I, Conrad M, Turker MZ, Gao M, Jiang X, Monette S, Pauliah M, Gonen M, Zanzonico P, Quinn T, Wiesner U, Bradbury MS, Overholtzer M. Ultrasmall nanoparticles induce ferroptosis in nutrient-deprived cancer cells and suppress tumour growth. Nature nanotechnology. 2016; 11(11):977-985. NIHMSID: NIHMS808620 PMCID: PMC5108575. PubMed

Collymore C, Crim MJ, Lieggi C. Recommendations for Health Monitoring and Reporting for Zebrafish Research Facilities. Zebrafish. 2016;13 Suppl 1:S138-48. doi: 10.1089/zeb.2015.1210. PubMed PMID: 26991393; PubMed Central PMCID: PMC4932782.

Redelsperger IM, Taldone T, Riedel ER, Lepherd ML, Lipman NS, Wolf FR. Stability of Doxycycline in Feed and Water and Minimal Effective Doses in Tetracycline-Inducible Systems. Journal of the American Association for Laboratory Animal Science : JAALAS. 2016;55(4):467-74. PubMed PMID: 27423155; PubMed Central PMCID: PMC4943619.

Alabi RO, Glomski K, Haxaire C, Weskamp G, Monette S., Blobel CP. ADAM10-Dependent Signaling Through Notch1 and Notch4 Controls Development of Organ-Specific Vascular Beds. Circulation research. 2016;119(4):519-31. doi: 10.1161/CIRCRESAHA.115.307738. PubMed PMID: 27354212; PubMed Central PMCID: PMC4975635.

Kaye EA, Monette S., Srimathveeravalli G, Maybody M, Solomon SB, Gulati A. MRI-guided focused ultrasound ablation of lumbar medial branch nerve: Feasibility and safety study in a swine model. International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group. 2016:1-9. doi: 10.1080/02656736.2016.1197972. PubMed PMID: 27443328.

Murray KS, Winter AG, Corradi RB, LaRosa S, Jebiwott S, Somma A, Takaki H, Srimathveeravalli G, Lepherd M, Monette S, Kim K, Scherz A, Coleman JA. Treatment Effects of WST11 Vascular Targeted Photodynamic Therapy for Urothelial Cell Carcinoma in Swine. The Journal of urology. 2016;196(1):236-43. doi: 10.1016/j.juro.2016.01.107. PubMed PMID: 26860792; PubMed Central PMCID: PMC4914469.

Sharma SK, Sevak KK, Monette S, Carlin SD, Knight JC, Wuest FR, Sala E, Zeglis BM, Lewis JS. Preclinical 89Zr Immuno-PET of High-Grade Serous Ovarian Cancer and Lymph Node Metastasis. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2016;57(5):771-6. doi: 10.2967/jnumed.115.167072. PubMed PMID: 26837339; PubMed Central PMCID: PMC4959443.

Kimm SY, Tarin TV, Monette S, Srimathveeravalli G, Gerber D, Durack JC, Solomon SB, Scardino PT, Scherz A, Coleman J. Nonthermal Ablation by Using Intravascular Oxygen Radical Generation with WST11: Dynamic Tissue Effects and Implications for Focal Therapy. Radiology. 2016:141571. doi: 10.1148/radiol.2016141571. PubMed PMID: 26986047.

Warner SG, Haddad D, Au J, Carson JS, O’Leary MP, Lewis C, Monette S, Fong Y. Oncolytic herpes simplex virus kills stem-like tumor-initiating colon cancer cells. Molecular therapy oncolytics. 2016;3:16013. doi: 10.1038/mto.2016.13. PubMed PMID: 27347556; PubMed Central PMCID: PMC4909096.

Rao TD, Tian H, Ma X, Yan X, Thapi S, Schultz N, Rosales N, Monette S, Wang A, Hyman DM, Levine DA, Solit D, Spriggs DR. Expression of the Carboxy-Terminal Portion of MUC16/CA125 Induces Transformation and Tumor Invasion. PloS one. 2015;10(5):e0126633. doi: 10.1371/journal.pone.0126633. PubMed PMID: 25965947; PubMed Central PMCID: PMC4429113.

Harmsen S, Huang R, Wall MA, Karabeber H, Samii JM, Spaliviero M, White JR, Monette S, O’Connor R, Pitter KL, Sastra SA, Saborowski M, Holland EC, Singer S, Olive KP, Lowe SW, Blasberg RG, Kircher MF. Surface-enhanced resonance Raman scattering nanostars for high-precision cancer imaging. Science translational medicine. 2015;7(271):271ra7. doi: 10.1126/scitranslmed.3010633. PubMed PMID: 25609167; PubMed Central PMCID: PMC4414254.

Li X, Maretzky T, Weskamp G, Monette S, Qing X, Issuree PD, Crawford HC, McIlwain DR, Mak TW, Salmon JE, Blobel CP. iRhoms 1 and 2 are essential upstream regulators of ADAM17-dependent EGFR signaling. Proceedings of the National Academy of Sciences of the United States of America. 2015;112(19):6080-5. doi: 10.1073/pnas.1505649112. PubMed PMID: 25918388; PubMed Central PMCID: PMC4434755.

Lee KS, Takaki H, Yarmohammadi H, Srimathveeravalli G, Luchins K, Monette S., Nair S, Kishore S, Erinjeri JP. Pleural puncture that excludes the ablation zone decreases the risk of pneumothorax after percutaneous microwave ablation in porcine lung. Journal of vascular and interventional radiology : JVIR. 2015;26(7):1052-8. doi: 10.1016/j.jvir.2015.01.016. PubMed PMID: 25753501.

Srimathveeravalli G, Silk M, Wimmer T, Monette S, Kimm S, Maybody M, Solomon SB, Coleman J, Durack JC. Feasibility of catheter-directed intraluminal irreversible electroporation of porcine ureter and acute outcomes in response to increasing energy delivery. Journal of vascular and interventional radiology : JVIR. 2015;26(7):1059-66. doi: 10.1016/j.jvir.2015.01.020. PubMed PMID: 25769212; PubMed Central PMCID: PMC4478125.

Kaye EA, Gutta NB, Monette S, Gulati A, Loh J, Srimathveeravalli G, Ezell PC, Erinjeri JP, Solomon SB, Maybody M. Feasibility Study on MR-Guided High-Intensity Focused Ultrasound Ablation of Sciatic Nerve in a Swine Model: Preliminary Results. Cardiovascular and interventional radiology. 2015;38(4):985-92. doi: 10.1007/s00270-015-1141-0. PubMed PMID: 26040256.

Wimmer T, Srimathveeravalli G, Silk M, Monette S, Gutta N, Maybody M, Erinjery JP, Coleman JA, Solomon SB, Sofocleous CT. Feasibility of a Modified Biopsy Needle for Irreversible Electroporation Ablation and Periprocedural Tissue Sampling. Technology in cancer research & treatment. 2015. doi: 10.1177/1533034615608739. PubMed PMID: 26443800.

Braden GC, Arbona RR, Lepherd M, Monette S, Toma A, Fox JG, Dewhirst FE, Lipman NS. A Novel alpha-Hemolytic Streptococcus Species (Streptococcus azizii sp. nov.) Associated with Meningoencephalitis in Naive Weanling C57BL/6 Mice. Comp Med. 2015;65(3):186-95. PubMed PMID: 26141443; PubMed Central PMCID: PMC4485627.

Dyke JP, Synan M, Ezell P, Ballon D, Racine J, Aaron RK. Characterization of bone perfusion by dynamic contrast-enhanced magnetic resonance imaging and positron emission tomography in the Dunkin-Hartley guinea pig model of advanced osteoarthritis. Journal of orthopaedic research : official publication of the Orthopaedic Research Society. 2015;33(3):366-72. doi: 10.1002/jor.22768. PubMed PMID: 25410523; PubMed Central PMCID: PMC4346481.

Milsom JW, Trencheva K, Ezell P, Maggiori L, Pavoor R, Vitellaro M, Zhuo C, Makino T, Lee SW, Shukla PJ. Feasibility and Safety of Laparoscopic Colon Surgery Performed Under Intravenous Sedation and Local Anesthesia Using Microinvasive (<3 mm) Instruments: An Acute and Survival Study on Porcine Model. Surgical innovation. 2015;22(2):131-6. doi: 10.1177/1553350614535854. PubMed PMID: 24902688.

Wimmer T, Srimathveeravalli G, Gutta N, Ezell PC, Monette S, Maybody M, Erinjery JP, Durack JC, Coleman JA, Solomon SB. Planning irreversible electroporation in the porcine kidney: are numerical simulations reliable for predicting empiric ablation outcomes? Cardiovascular and interventional radiology. 2015;38(1):182-90. doi: 10.1007/s00270-014-0905-2. PubMed PMID: 24831827.

Diaz LL, Zhang J, Heerdt PM. Comparative pharmacodynamics of pancuronium, cisatracurium, and CW002 in rabbits. Journal of the American Association for Laboratory Animal Science : JAALAS. 2014;53(3):283-9. PubMed PMID: 24827571; PubMed Central PMCID: PMC4128567.

Fujisawa S, Romin Y, Barlas A, Petrovic LM, Turkekul M, Fan N, Xu K, Garcia AR, Monette S, Klimstra DS, Erinjeri JP, Solomon SB, Manova-Todorova K, Sofocleous CT. Evaluation of YO-PRO-1 as an early marker of apoptosis following radiofrequency ablation of colon cancer liver metastases. Cytotechnology. 2014;66(2):259-73. doi: 10.1007/s10616-013-9565-3. PubMed PMID: 24065619; PubMed Central PMCID: PMC3918265.

Blachere NE, Orange DE, Santomasso BD, Doerner J, Foo PK, Herre M, Fak J, Monette S, Gantman EC, Frank MO, Darnell RB. T cells targeting a neuronal paraneoplastic antigen mediate tumor rejection and trigger CNS autoimmunity with humoral activation. European journal of immunology. 2014;44(11):3240-51. doi: 10.1002/eji.201444624. PubMed PMID: 25103845; PubMed Central PMCID: PMC4296561.

Chung SS, Kim E, Park JH, Chung YR, Lito P, Teruya-Feldstein J, Hu W, Beguelin W, Monette S, Duy C, Rampal R, Telis L, Patel M, Kim MK, Huberman K, Bouvier N, Berger MF, Melnick AM, Rosen N, Tallman MS, Park CY, Abdel-Wahab O. Hematopoietic stem cell origin of BRAFV600E mutations in hairy cell leukemia. Science translational medicine. 2014;6(238):238ra71. doi: 10.1126/scitranslmed.3008004. PubMed PMID: 24871132; PubMed Central PMCID: PMC4501573.

Collymore C, Porelli G, Lieggi C, Lipman NS. Evaluation of 5 cleaning and disinfection methods for nets used to collect zebrafish (Danio rerio). Journal of the American Association for Laboratory Animal Science : JAALAS. 2014;53(6):657-60. PubMed PMID: 25650972; PubMed Central PMCID: PMC4253579.

Collymore C, Tolwani A, Lieggi C, Rasmussen S. Efficacy and safety of 5 anesthetics in adult zebrafish (Danio rerio). Journal of the American Association for Laboratory Animal Science : JAALAS. 2014;53(2):198-203. PubMed PMID: 24602548; PubMed Central PMCID: PMC3966278.

Collymore C, Watral V, White JR, Colvin ME, Rasmussen S, Tolwani RJ, Kent ML. Tolerance and efficacy of emamectin benzoate and ivermectin for the treatment of Pseudocapillaria tomentosa in laboratory zebrafish (Danio rerio). Zebrafish. 2014;11(5):490-7. doi: 10.1089/zeb.2014.1021. PubMed PMID: 25237985; PubMed Central PMCID: PMC4172560.

Correa-Gallego C, Karkar AM, Monette S, Ezell PC, Jarnagin WR, Kingham TP. Intraoperative ultrasound and tissue elastography measurements do not predict the size of hepatic microwave ablations. Academic radiology. 2014;21(1):72-8. doi: 10.1016/j.acra.2013.09.022. PubMed PMID: 24331267.

Gulati A, Loh J, Gutta NB, Ezell PC, Monette S, Erinjeri JP, Maybody M, Solomon S. Novel use of noninvasive high-intensity focused ultrasonography for intercostal nerve neurolysis in a swine model. Regional anesthesia and pain medicine. 2014;39(1):26-30. doi: 10.1097/AAP.0000000000000028. PubMed PMID: 24317231.

Hicks MJ, Kaminsky SM, De BP, Rosenberg JB, Evans SM, Foltin RW, Andrenyak DM, Moody DE, Koob GF, Janda KD, Ricart Arbona RJ, Lepherd ML, Crystal RG. Fate of systemically administered cocaine in nonhuman primates treated with the dAd5GNE anticocaine vaccine. Human gene therapy Clinical development. 2014;25(1):40-9. doi: 10.1089/humc.2013.231. PubMed PMID: 24649839; PubMed Central PMCID: PMC4047994.

Paluch LR, Lieggi CC, Dumont M, Monette S, Riedel ER, Lipman NS. Developmental and behavioral effects of toe clipping on neonatal and preweanling mice with and without vapocoolant anesthesia. Journal of the American Association for Laboratory Animal Science : JAALAS. 2014;53(2):132-40. PubMed PMID: 24602538; PubMed Central PMCID: PMC3966268.

Rosenberg JB, Sondhi D, Rubin DG, Monette S, Chen A, Cram S, De BP, Kaminsky SM, Sevin C, Aubourg P, Crystal RG. Comparative efficacy and safety of multiple routes of direct CNS administration of adeno-associated virus gene transfer vector serotype rh.10 expressing the human arylsulfatase A cDNA to nonhuman primates. Human gene therapy Clinical development. 2014;25(3):164-77. doi: 10.1089/humc.2013.239. PubMed PMID: 25144894; PubMed Central PMCID: PMC4227442.

Srimathveeravalli G, Kim C, Petrisor D, Ezell P, Coleman J, Hricak H, Solomon SB, Stoianovici D. MRI-safe robot for targeted transrectal prostate biopsy: animal experiments. BJU international. 2014;113(6):977-85. doi: 10.1111/bju.12335. PubMed PMID: 24118992.

Sui Y, Park SH, Xu J, Monette S, Helsley RN, Han SS, Zhou C. IKKbeta links vascular inflammation to obesity and atherosclerosis. The Journal of experimental medicine. 2014;211(5):869-86. doi: 10.1084/jem.20131281. PubMed PMID: 24799533; PubMed Central PMCID: PMC4010900.

Such KA, Petraitis V, Petraitiene R, Strauss GE, Moradi PW, Walsh TJ. Environmental monitoring for Aspergillus fumigatus in association with an immunosuppressed rabbit model of pulmonary aspergillosis. Journal of the American Association for Laboratory Animal Science : JAALAS. 2013;52(5):541-4. PubMed PMID: 24041208; PubMed Central PMCID: PMC3784658.

Abdel-Wahab O, Gao J, Adli M, Dey A, Trimarchi T, Chung YR, Kuscu C, Hricik T, Ndiaye-Lobry D, Lafave LM, Koche R, Shih AH, Guryanova OA, Kim E, Li S, Pandey S, Shin JY, Telis L, Liu J, Bhatt PK, Monette S, Zhao X, Mason CE, Park CY, Bernstein BE, Aifantis I, Levine RL. Deletion of Asxl1 results in myelodysplasia and severe developmental defects in vivo. The Journal of experimental medicine. 2013;210(12):2641-59. doi: 10.1084/jem.20131141. PubMed PMID: 24218140; PubMed Central PMCID: PMC3832937.

Au JT, Kingham TP, Jun K, Haddad D, Gholami S, Mojica K, Monette S, Ezell P, Fong Y. Irreversible electroporation ablation of the liver can be detected with ultrasound B-mode and elastography. Surgery. 2013;153(6):787-93. doi: 10.1016/j.surg.2012.11.022. PubMed PMID: 23489942.

Au JT, Mittra A, Song TJ, Cavnar M, Jun K, Carson J, Gholami S, Haddad D, Gaujoux S, Monette S, Ezell P, Wolchok J, Fong Y. Irreversible electroporation facilitates gene transfer of a GM-CSF plasmid with a local and systemic response. Surgery. 2013;154(3):496-503. doi: 10.1016/j.surg.2013.06.005. PubMed PMID: 23972655; PubMed Central PMCID: PMC4140181.

Collymore C, White JR, Lieggi C. Trichodina xenopodus, a ciliated protozoan, in a laboratory-maintained Xenopus laevis. Comp Med. 2013;63(4):310-2. PubMed PMID: 24209965; PubMed Central PMCID: PMC3750665.

Corse E, Gottschalk RA, Park JS, Sepulveda MA, Loke P, Sullivan TJ, Johnson LK, Allison JP. Cutting edge: chronic inflammatory liver disease in mice expressing a CD28-specific ligand. Journal of immunology. 2013;190(2):526-30. doi: 10.4049/jimmunol.1202621. PubMed PMID: 23248264.

Diaz LL, Lepherd M, Scott J. Enteric infection and subsequent septicemia due to attaching and effacing Escherichia coli in a Chinchilla. Comp Med. 2013;63(6):503-7. PubMed PMID: 24326226; PubMed Central PMCID: PMC3866984.

Hartrampf S, Dudakov JA, Johnson LK, Smith OM, Tsai J, Singer NV, West ML, Hanash AM, Albert MH, Liu B, Toth M, van den Brink MR. The central nervous system is a target of acute graft versus host disease in mice. Blood. 2013;121(10):1906-10. doi: 10.1182/blood-2012-09-456590. PubMed PMID: 23299314; PubMed Central PMCID: PMC3591808.

Issuree PD, Maretzky T, McIlwain DR, Monette S, Qing X, Lang PA, Swendeman SL, Park-Min KH, Binder N, Kalliolias GD, Yarilina A, Horiuchi K, Ivashkiv LB, Mak TW, Salmon JE, Blobel CP. iRHOM2 is a critical pathogenic mediator of inflammatory arthritis. The Journal of clinical investigation. 2013;123(2):928-32. doi: 10.1172/JCI66168. PubMed PMID: 23348744; PubMed Central PMCID: PMC3561822.

Kaminsky SM, Quach L, Chen S, Pierre-Destine L, Van de Graaf B, Monette S, Rosenberg JB, De BP, Sondhi D, Hackett NR, Mezey JG, Rosengart TK, Crystal RG. Safety of direct cardiac administration of AdVEGF-All6A+, a replication-deficient adenovirus vector cDNA/genomic hybrid expressing all three major isoforms of human vascular endothelial growth factor, to the ischemic myocardium of rats. Human gene therapy Clinical development. 2013;24(1):38-46. doi: 10.1089/humc.2013.054. PubMed PMID: 23692382.

Liu X, He Y, Xiao K, White JR, Fusco DN, Papanicolaou GA. Effect of linezolid on clinical severity and pulmonary cytokines in a murine model of influenza A and Staphylococcus aureus coinfection. PloS one. 2013;8(3):e57483. doi: 10.1371/journal.pone.0057483. PubMed PMID: 23478252; PubMed Central PMCID: PMC3589409.

Orange DE, Blachere NE, Fak J, Parveen S, Frank MO, Herre M, Tian S, Monette S, Darnell RB. Dendritic cells loaded with FK506 kill T cells in an antigen-specific manner and prevent autoimmunity in vivo. eLife. 2013;2:e00105. doi: 10.7554/eLife.00105. PubMed PMID: 23390586; PubMed Central PMCID: PMC3564474.

Power NE, Silberstein JL, Tarin T, Au J, Thorner D, Ezell P, Monette S, Fong Y, Rusch V, Finley D, Coleman JA. Endoscopic spray cryotherapy for genitourinary malignancies: safety and efficacy in a porcine model. Therapeutic advances in urology. 2013;5(3):135-41. doi: 10.1177/1756287212465457. PubMed PMID: 23730328; PubMed Central PMCID: PMC3655355.

Schoellnast H, Monette S, Ezell PC, Single G, Maybody M, Weiser MR, Fong Y, Solomon SB. Irreversible electroporation adjacent to the rectum: evaluation of pathological effects in a pig model. Cardiovascular and interventional radiology. 2013;36(1):213-20. doi: 10.1007/s00270-012-0393-1. PubMed PMID: 22562481.

Schoellnast H, Monette S, Ezell PC, Maybody M, Erinjeri JP, Stubblefield MD, Single G, Solomon SB. The delayed effects of irreversible electroporation ablation on nerves. European radiology. 2013;23(2):375-80. doi: 10.1007/s00330-012-2610-3. PubMed PMID: 23011210.

Schoellnast H, Monette S, Ezell PC, Keene A, Quehenberger F, Erinjeri JP, Solomon SB. Interstitial laser-induced thermotherapy of the lung: evaluation of the influence of ablation continuity on ablation size in a swine model. Cancer imaging : the official publication of the International Cancer Imaging Society. 2013;13:8-13. doi: 10.1102/1470-7330.2013.0002. PubMed PMID: 23439016; PubMed Central PMCID: PMC3581868.

Srimathveeravalli G, Wimmer T, Monette S, Gutta NB, Ezell PC, Maybody M, Weiser MR, Solomon SB. Evaluation of an endorectal electrode for performing focused irreversible electroporation ablations in the Swine rectum. Journal of vascular and interventional radiology : JVIR. 2013;24(8):1249-56. doi: 10.1016/j.jvir.2013.04.025. PubMed PMID: 23796856.

Wimmer T, Srimathveeravalli G, Gutta N, Ezell PC, Monette S, Kingham TP, Maybody M, Durack JC, Fong Y, Solomon SB. Comparison of simulation-based treatment planning with imaging and pathology outcomes for percutaneous CT-guided irreversible electroporation of the porcine pancreas: a pilot study. Journal of vascular and interventional radiology : JVIR. 2013;24(11):1709-18. doi: 10.1016/j.jvir.2013.05.056. PubMed PMID: 23891044.

Whipps CM, Lieggi C., Wagner R. Mycobacteriosis in zebrafish colonies. ILAR journal / National Research Council, Institute of Laboratory Animal Resources. 2012;53(2):95-105. doi: 10.1093/ilar.53.2.95. PubMed PMID: 23382341. 

Sondhi D, Johnson L, Purpura K, Monette S, Souweidane MM, Kaplitt MG, Kosofsky B, Yohay K, Ballon D, Dyke J, Kaminksy SM, Hackett NR, Crystal RG. Long-term expression and safety of administration of AAVrh.10hCLN2 to the brain of rats and nonhuman primates for the treatment of late infantile neuronal ceroid lipofuscinosis. Human gene therapy methods. 2012;23(5):324-35. doi: 10.1089/hgtb.2012.120. PubMed PMID: 23131032; PubMed Central PMCID: PMC3847998. 

Au JT, Mittra A, Wong J, Carpenter S, Carson J, Haddad D, Monette S, Ezell P, Patel S, Fong Y. Flexible CO2 laser and submucosal gel injection for safe endoluminal resection in the intestines. Surgical endoscopy. 2012;26(1):47-52. doi: 10.1007/s00464-011-1826-7. PubMed Central PMCID: PMC3275344.

Au JT, Carson J, Monette S, Finley DJ. Spray cryotherapy is effective for bronchoscopic, endoscopic and open ablation of thoracic tissues. Interactive cardiovascular and thoracic surgery. 2012;15(4):580-4. doi: 10.1093/icvts/ivs192. PubMed PMID: 22811511; PubMed Central PMCID: PMC3445345. 

Burr HN, Wolf FR, Lipman NS. Corynebacterium bovis: epizootiologic features and environmental contamination in an enzootically infected rodent room. Journal of the American Association for Laboratory Animal Science : JAALAS. 2012;51(2):189-98. PubMed PMID: 22776119; PubMed Central PMCID: PMC3314522. 

Cassano AE, White JR, Penraat KA, Wilson CD, Rasmussen S, Karatsoreos IN. Anatomic, hematologic, and biochemical features of C57BL/6NCrl mice maintained on chronic oral corticosterone. Comp Med. 2012;62(5):348-60. PubMed PMID: 23114038; PubMed Central PMCID: PMC3472599. 

Milsom J, Trencheva K, Monette S, Pavoor R, Shukla P, Ma J, Sonoda T. Evaluation of the safety, efficacy, and versatility of a new surgical energy device (THUNDERBEAT) in comparison with Harmonic ACE, LigaSure V, and EnSeal devices in a porcine model. Journal of laparoendoscopic & advanced surgical techniques Part A. 2012;22(4):378-86. doi: 10.1089/lap.2011.0420. PubMed PMID: 22364404. 

Roble GS, Boteler W, Riedel E, Lipman NS. Total IgE as a serodiagnostic marker to aid murine fur mite detection. Journal of the American Association for Laboratory Animal Science : JAALAS. 2012;51(2):199-208. PubMed PMID: 22776120; PubMed Central PMCID: PMC3314523.

Roble GS, Gillespie V, Lipman NS. Infectious disease survey of Mus musculus from pet stores in New York City. Journal of the American Association for Laboratory Animal Science : JAALAS. 2012;51(1):37-41. PubMed PMID: 22330866; PubMed Central PMCID: PMC3276964.

Whipps CM, Lieggi C, Wagner R. Mycobacteriosis in zebrafish colonies. ILAR journal / National Research Council, Institute of Laboratory Animal Resources. 2012;53(2):95-105. doi: 10.1093/ilar.53.2.95. PubMed PMID: 23382341. 

Xiong X, Chorzalska A, Dubielecka PM, White JR, Vedvyas Y, Hedvat CV, Haimovitz-Friedman A, Koutcher JA, Reimand J, Bader GD, Sawicki JA, Kotula L. Disruption of Abi1/Hssh3bp1 expression induces prostatic intraepithelial neoplasia in the conditional Abi1/Hssh3bp1 KO mice. Oncogenesis. 2012;1:e26. doi: 10.1038/oncsis.2012.28. PubMed PMID: 23552839; PubMed Central PMCID: PMC3503296. 

Au JT, Wong J, Mittra A, Carpenter S, Haddad D, Carson J, Jayaraman S, Monette S, Solomon SB, Ezell P, Fong Y. Irreversible electroporation is a surgical ablation technique that enhances gene transfer. Surgery. 2011;150(3):474-9. doi: 10.1016/j.surg.2011.07.007. PubMed Central PMCID: PMC3266825.

Burr HN, Lipman NS, White JR, Zheng J, Wolf FR. Strategies to prevent, treat, and provoke Corynebacterium-associated hyperkeratosis in athymic nude mice. Journal of the American Association for Laboratory Animal Science: JAALAS. 2011;50(3):378-88. PubMed Central PMCID: PMC3103290. PubMed

Clegg NJ, Couto SS, Wongvipat J, Hieronymus H, Carver BS, Taylor BS, Ellwood-Yen K, Gerald WL, Sander C, Sawyers CL. MYC cooperates with AKT in prostate tumorigenesis and alters sensitivity to mTOR inhibitors. PloS one. 2011;6(3):e17449. doi: 10.1371/journal.pone.0017449. PubMed; PubMed Central PMCID: PMC3048873.

Deodhar A, Monette S, Single GW, Jr., Hamilton WC, Jr., Thornton R, Maybody M, Coleman JA, Solomon SB. Renal tissue ablation with irreversible electroporation: preliminary results in a porcine model. Urology. 2011;77(3):754-60. doi: 10.1016/j.urology.2010.08.036. PubMed

Deodhar A, Monette S, Single GW, Jr., Hamilton WC, Jr., Thornton RH, Sofocleous CT, Maybody M, Solomon SB. Percutaneous irreversible electroporation lung ablation: preliminary results in a porcine model. Cardiovascular and interventional radiology. 2011;34(6):1278-87. doi: 10.1007/s00270-011-0143-9. PubMed

Donkor MK, Sarkar A, Savage PA, Franklin RA, Johnson LK, Jungbluth AA, Allison JP, Li MO. T cell surveillance of oncogene-induced prostate cancer is impeded by T cell-derived TGF-beta1 cytokine. Immunity. 2011;35(1):123-34. doi: 10.1016/j.immuni.2011.04.019. PubMed; PubMed Central PMCID: PMC3430371.

Glomski K, Monette S, Manova K, De Strooper B, Saftig P, Blobel CP. Deletion of Adam10 in endothelial cells leads to defects in organ-specific vascular structures. Blood. 2011;118(4):1163-74. doi: 10.1182/blood-2011-04-348557. PubMed; PubMed Central PMCID: PMC3148163.

Gravaghi C, La Perle KM, Ogrodwski P, Kang JX, Quimby F, Lipkin M, Lamprecht SA. Cox-2 expression, PGE(2) and cytokines production are inhibited by endogenously synthesized n-3 PUFAs in inflamed colon of fat-1 mice. The Journal of nutritional biochemistry. 2011;22(4):360-5. doi: 10.1016/j.jnutbio.2010.03.003. PubMed

Rasmussen S, Miller MM, Filipski SB, Tolwani RJ. Cage change influences serum corticosterone and anxiety-like behaviors in the mouse. Journal of the American Association for Laboratory Animal Science : JAALAS. 2011;50(4):479-83. PubMed; PubMed Central PMCID: PMC3148651.

Rezende NC, Lee MY, Monette S, Mark W, Lu A, Gudas LJ. Rex1 (Zfp42) null mice show impaired testicular function, abnormal testis morphology, and aberrant gene expression. Developmental biology. 2011;356(2):370-82. doi: 10.1016/j.ydbio.2011.05.664. PubMed; PubMed Central PMCID: PMC3214085.

Schoellnast H, Monette S, Ezell PC, Deodhar A, Maybody M, Erinjeri JP, Stubblefield MD, Single GW, Jr., Hamilton WC, Jr., Solomon SB. Acute and subacute effects of irreversible electroporation on nerves: experimental study in a pig model. Radiology. 2011;260(2):421-7. doi: 10.1148/radiol.11103505. PubMed

Servais EL, Colovos C, Bograd AJ, White J, Sadelain M, Adusumilli PS. Animal models and molecular imaging tools to investigate lymph node metastases. Journal of molecular medicine. 2011;89(8):753-69. doi: 10.1007/s00109-011-0764-0. PubMed ; PubMed Central PMCID: PMC3269816.

Ricart Arbona RJ, Lipman NS, Riedel ER, Wolf FR. Treatment and eradication of murine fur mites: I. Toxicologic evaluation of ivermectin-compounded feed. Journal of the American Association for Laboratory Animal Science : JAALAS. 2010;49(5):564-70. PubMed; PubMed Central PMCID: PMC2949424.

Ricart Arbona RJ, Lipman NS, Wolf FR. Treatment and eradication of murine fur mites: II. Diagnostic considerations. Journal of the American Association for Laboratory Animal Science : JAALAS. 2010;49(5):583-7. PubMed; PubMed Central PMCID: PMC2949427.

Ricart Arbona RJ, Lipman NS, Wolf FR. Treatment and eradication of murine fur mites: III. Treatment of a large mouse colony with ivermectin-compounded feed. Journal of the American Association for Laboratory Animal Science : JAALAS. 2010;49(5):633-7. PubMed; PubMed Central PMCID: PMC2949434.

Roble GS, Lingenhol NM, Baker B, Wilkerson A, Tolwani RJ. A comprehensive laboratory animal facility pandemic response plan. Journal of the American Association for Laboratory Animal Science : JAALAS. 2010;49(5):623-32. PubMed; PubMed Central PMCID: PMC2949433.

Roepke TK, Purtell K, King EC, La Perle KM, Lerner DJ, Abbott GW. Targeted deletion of Kcne2 causes gastritis cystica profunda and gastric neoplasia. PloS one. 2010;5(7):e11451. doi: 10.1371/journal.pone.0011451. PubMed; PubMed Central PMCID: PMC2897890.

Ruggiero A, Brader P, Serganova I, Zanzonico P, Cai S, Lipman NS, Hricak H, Blasberg RG. Different strategies for reducing intestinal background radioactivity associated with imaging HSV1-tk expression using established radionucleoside probes. Molecular imaging. 2010;9(1):47-58. PubMed; PubMed Central PMCID: PMC3068838.

Traslavina RP, King EJ, Loar AS, Riedel ER, GarveyMS, Ricart-Arbona R, Wolf FR, Couto SS. Euthanasia by CO(2) inhalation affects potassium levels in mice. Journal of the American Association for Laboratory Animal Science : JAALAS. 2010;49(3):316-22. PubMed; PubMed Central PMCID: PMC2877304.

Couto SS, Cao M, Duarte PC, Banach-Petrosky W, Wang S, Romanienko P, Wu H, Cardiff RD, Abate-Shen C, Cunha GR. Simultaneous haploinsufficiency of Pten and Trp53 tumor suppressor genes accelerates tumorigenesis in a mouse model of prostate cancer. Differentiation; research in biological diversity. 2009;77(1):103-11. doi: 10.1016/j.diff.2008.09.010. PubMed; PubMed Central PMCID: PMC2828345.

King JC, Xu J, Wongvipat J, Hieronymus H, Carver BS, Leung DH, Taylor BS, Sander C, Cardiff RD, Couto SS, Gerald WL, Sawyers CL. Cooperativity of TMPRSS2-ERG with PI3-kinase pathway activation in prostate oncogenesis. Nature genetics. 2009;41(5):524-6. doi: 10.1038/ng.371. PubMed; PubMed Central PMCID: PMC2898503.

Postel EH, Wohlman I, Zou X, Juan T, Sun N, D’Agostin D, Cuellar M, Choi T, Notterman DA, La Perle KM. Targeted deletion of Nm23/nucleoside diphosphate kinase A and B reveals their requirement for definitive erythropoiesis in the mouse embryo. Developmental dynamics : an official publication of the American Association of Anatomists. 2009;238(3):775-87. doi: 10.1002/dvdy.21887. PubMed

Postel EH, Zou X, Notterman DA, La Perle KM. Double knockout Nme1/Nme2 mouse model suggests a critical role for NDP kinases in erythroid development. Molecular and cellular biochemistry. 2009;329(1-2):45-50. doi: 10.1007/s11010-009-0110-9. PubMed

Rasmussen S, Glickman G, Norinsky R, Quimby FW, Tolwani RJ. Construction noise decreases reproductive efficiency in mice. Journal of the American Association for Laboratory Animal Science : JAALAS. 2009;48(4):363-70. PubMed; PubMed Central PMCID: PMC2715925.

Santos EB, Yeh R, Lee J, Nikhamin Y, Punzalan B, Punzalan B, La Perle K, Larson SM, Sadelain M, Brentjens RJ. Sensitive in vivo imaging of T cells using a membrane-bound Gaussia princeps luciferase. Nature medicine. 2009;15(3):338-44. doi: 10.1038/nm.1930. PubMed; PubMed Central PMCID: PMC2837150.

Stracker TH, Couto SS, Cordon-Cardo C, Matos T, Petrini JH. Chk2 suppresses the oncogenic potential of DNA replication-associated DNA damage. Molecular cell. 2008;31(1):21-32. doi: 10.1016/j.molcel.2008.04.028. PubMed; PubMed Central PMCID: PMC2586815.

Couto SS, Cardiff RD. The genomic revolution and endocrine pathology. Endocrine pathology. 2008;19(3):139-47. doi: 10.1007/s12022-008-9042-2. PubMed

Hockemeyer D, Palm W, Wang RC, Couto SS, de Lange T. Engineered telomere degradation models dyskeratosis congenita. Genes & development. 2008;22(13):1773-85. doi: 10.1101/gad.1679208. PubMed; PubMed Central PMCID: PMC2492664. [PMID: 18550783]

Brentjens RJ, Santos E, Nikhamin Y, Yeh R, Matsushita M, La Perle K, Quintas-Cardama A, Larson SM, Sadelain M. Genetically targeted T cells eradicate systemic acute lymphoblastic leukemia xenografts. Clinical cancer research : an official journal of the American Association for Cancer Research. 2007;13(18 Pt 1):5426-35. doi: 10.1158/1078-0432.CCR-07-0674. PubMed

Cohen JK, Cai LQ, Zhu YS, La Perle KM. Pancreaticoduodenal arterial rupture and hemoabdomen in ACI/SegHsd rats with polyarteritis nodosa. Comp Med. 2007;57(4):370-6. PubMed

McIntyre A, La Perle KM. Hermaphroditism in 3 chimeric mice. Veterinary pathology. 2007;44(2):249-52. doi: 10.1354/vp.44-2-249. PubMed

McIntyre AR, Drummond RA, Riedel ER, Lipman NS. Automated mouse euthanasia in an individually ventilated caging system: system development and assessment. Journal of the American Association for Laboratory Animal Science : JAALAS. 2007;46(2):65-73. PubMed

McIntyre AR, Lipman NS. Amoxicillin-clavulanic acid and trimethoprim- sulfamethoxazole in rodent feed and water: effects of compounding on antibiotic stability. Journal of the American Association for Laboratory Animal Science : JAALAS. 2007;46(5):26-32. PubMed

Mutlu AD, Cavallin LE, Vincent L, Chiozzini C, Eroles P, Duran EM, Asgari Z, Hooper AT, La Perle KM, Hilsher C, Gao SJ, Dittmer DP, Rafii S, Mesri EA. In vivo-restricted and reversible malignancy induced by human herpesvirus-8 KSHV: a cell and animal model of virally induced Kaposi’s sarcoma. Cancer cell. 2007;11(3):245-58. doi: 10.1016/j.ccr.2007.01.015. PubMed; PubMed Central PMCID: PMC2180156.

Stracker TH, Morales M, Couto SS, Hussein H, Petrini JH. The carboxy terminus of NBS1 is required for induction of apoptosis by the MRE11 complex. Nature. 2007;447(7141):218-21. doi: 10.1038/nature05740. PubMed; PubMed Central PMCID: PMC3089978.

Thurlow RW, Arriola R, Soll CE, Lipman NS. Evaluation of a flash disinfection process for surface decontamination of gamma-irradiated feed packaging. Journal of the American Association for Laboratory Animal Science : JAALAS. 2007;46(4):46-9. PubMed

Altholtz LY, La Perle KMD, Quimby FW. Dose-dependant hypothyroidism in mice induced by commercial trimethoprim-sulfamethoxazole rodent feed. Comparative Med. 2006;56(5):395-401. PubMed PMID: WOS:000241270600003.

Mark WH, Romanienko P, Lipman N, Lacy E. The new transgenic mouse core: no longer a facility just for making mice. Lab animal. 2006;35(10):27-34. doi: 10.1038/laban1106-27. PubMed

Lipman NS, Jackson LR, Trudel LJ, Weis-Garcia F. Monoclonal versus polyclonal antibodies: distinguishing characteristics, applications, and information resources. ILAR journal / National Research Council, Institute of Laboratory Animal Resources. 2005;46(3):258-68. PubMed

Nathan C, Calingasan N, Nezezon J, Ding A, Lucia MS, La Perle K, Fuortes M, Lin M, Ehrt S, Kwon NS, Chen J, Vodovotz Y, Kipiani K, Beal MF. Protection from Alzheimer’s-like disease in the mouse by genetic ablation of inducible nitric oxide synthase. The Journal of experimental medicine. 2005;202(9):1163-9. doi: 10.1084/jem.20051529. PubMed; PubMed Central PMCID: PMC2213235.

Parisi MA, Lipman NS, Clarke CM, Taylor B, Kapur RP. Evaluation of Hox11L1 in the fmc/fmc rat model of chronic intestinal pseudo-obstruction. Journal of pediatric surgery. 2005;40(11):1760-5. doi: 10.1016/j.jpedsurg.2005.07.010. PubMed

Shen Y, La Perle KM, Levy DE, Darnell JE, Jr. Reduced STAT3 activity in mice mimics clinical disease syndromes. Biochemical and biophysical research communications. 2005;330(1):305-9. doi: 10.1016/j.bbrc.2005.02.154. PubMed

Veugelers M, Wilkes D, Burton K, McDermott DA, Song Y, Goldstein MM, La Perle K, Vaughan CJ, O’Hagan A, Bennett KR, Meyer BJ, Legius E, Karttunen M, Norio R, Kaariainen H, Lavyne M, Neau JP, Richter G, Kirali K, Farnsworth A, Stapleton K, Morelli P, Takanashi Y, Bamforth JS, Eitelberger F, Noszian I, Manfroi W, Powers J, Mochizuki Y, Imai T, Ko GT, Driscoll DA, Goldmuntz E, Edelberg JM, Collins A, Eccles D, Irvine AD, McKnight GS, Basson CT. Comparative PRKAR1A genotype-phenotype analyses in humans with Carney complex and prkar1a haploinsufficient mice. Proceedings of the National Academy of Sciences of the United States of America. 2004;101(39):14222-7. doi: 10.1073/pnas.0405535101. PubMed; PubMed Central PMCID: PMC521100.

Lipman NS, Homberger FR. Rodent quality assurance testing: use of sentinel animal systems. Lab animal. 2003;32(5):36-43. doi: 10.1038/laban0503-36. PubMed

Lipman NS, Perkins S, Nguyen H, Pfeffer M, Meyer H. Mousepox resulting from use of ectromelia virus-contaminated, imported mouse serum. Comp Med. 2000;50(4):426-35. PubMed

Lohmiller J, Lipman N. Silicon Crystals in Water of Autoclaved Glass Bottles. Contemporary topics in laboratory animal science / American Association for Laboratory Animal Science. 1998;37(1):62-5. PubMed

Tu H, Diberadinis LJ, Lipman NS. Determination of Air Distribution, Exchange, Velocity, and Leakage in Three Individually Ventilated Rodent Caging Systems. Contemporary topics in laboratory animal science / American Association for Laboratory Animal Science. 1997;36(1):69-73. PubMed