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Learn about what DNA repair looks like under a microscope.
… Friday, May 19, 2017 Summary When DNA is damaged, a cell stops dividing and recruits “lifeguard proteins” and repair proteins to get its life cycle back on track. The first microscope was invented almost 500 years ago, when two Dutch scientists placed lenses in a tube and found that they could magnify
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News
MSK investigators report exciting results for a new molecule that can block 16 different mutated forms of the KRAS protein. In the lab, the compound was effective against many cancer cell lines and in mouse models of lung cancer and colorectal cancer.
… Wednesday, May 31, 2023 KRAS was one of the first cancer genes ever discovered, but for a long time the cancer-causing KRAS protein was considered “undruggable” with targeted therapy. That started to change in May 2021, when the Food and Drug Administration granted accelerated approval to sotorasib (
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News
Cycle for Survival, the official rare cancer fundraising event of Memorial Sloan Kettering Cancer Center (MSK), will begin its 2024 signature team stationary-cycling events. As the founding partner of Cycle for Survival, Equinox will have its instructors leading high-energy rides across the country. 100% of the funds raised go directly to rare cancer research at MSK.
… Friday, February 2, 2024 Cycle for Survival, the official rare cancer fundraiser for Memorial Sloan Kettering Cancer Center (MSK), will kick off its annual team stationary-cycling fundraising events this weekend. Its community of people with rare cancers, survivors, caregivers, supporters, doctors, researchers
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The Samuel Bakhoum Lab
Our laboratory employs an interdisciplinary approach combining cell biology and biochemistry, as well as mouse and computational models to dissect the contributions of chromosomal instability toward three key processes in human cancer: therapeutic resistance, immune evasion, and metastasis.
… Our laboratory employs an interdisciplinary approach combining cell biology, biochemistry, as well as mouse and computational models to dissect the contributions of chromosomal instability (CIN) toward three key processes in human cancer: therapeutic resistance, immune evasion, and metastasis. Major
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News
An analysis of germline DNA in people with advanced cancer finds that inherited mutations may be more common than expected in this group.
… Tuesday, September 5, 2017 Summary An analysis of germline DNA in people with advanced cancer finds that inherited mutations may be more common than expected in this group. The findings have implications for genetic counseling and screening. Memorial Sloan Kettering’s genomic-sequencing test, called
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News
September is Pediatric Cancer Awareness Month and at MSK, we continue to work to advance research to bring about better treatments and awareness to our youngest and most vulnerable patients not only in September, but every day.
… Tuesday, September 1, 2020 When we think about progress in fighting cancer, some of the most hopeful stories over the last few years have involved advances in treating children diagnosed with pediatric cancers. Once uniformly fatal, today, many children are thriving, beating the odds that once were stacked
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The Hans-Guido Wendel Lab
… Job Title Graduate Student Email [email protected] Lab Phone 646-888-2528
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The David Scheinberg Lab
Principal Scientific Communication Lead at Genentech, San Francisco, CA
… Job Title Principal Scientific Communication Lead at Genentech, San Francisco, CA Science is constantly moving forward. It is never stagnant, and it pushes the boundaries of what we know and believe every second of every day. Being part of that is an amazing thing. In addition to my passion for science
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Clinical Trial
… Full Title A Phase 3, Open-label, Multicenter, Randomized Study of Xaluritamig vs Cabazitaxel or Second Androgen Receptor-Directed Therapy in Subjects With Metastatic Castration-Resistant Prostate Cancer Previously Treated With Chemotherapy (WCG) Purpose Prostate cancers initially need the male hormone