Ascertainment of Families for Genetic Studies of Familial Lymphoproliferative Disorders

Full Title

Purpose

This study aims to obtain a better understanding of the genetic causes of Hodgkin’s disease (a kind of lymphoma) and non-Hodgkin’s lymphoma, as well as multiple myeloma, leukemia, and related diseases. Together these diseases are referred to as “lymphoproliferative disorders.”

Participants in the study will include: (1) patients who have had a lymphoproliferative disorder such as lymphoma, leukemia, or multiple myeloma, and have a family member with one of these disorders, or (2) individuals who are a member of a family with more than one case of a lymphoproliferative disorder. Study data will be collected by analyzing blood samples as well as family medical history.

The goal of the study is to identify genetic changes that may predict a person’s risk of developing one of these diseases. Research methods will involve sequencing to discover new genes. (Note: The results of individual research blood tests cannot be provided to participants; however, an overall summary of the research findings will be communicated to all interested enrollees.)