I am a medical oncologist with clinical and laboratory experience in cancer genetics. My research focuses on defining genetic factors that cause an increased susceptibility to cancer. My research team identified the most common mutation associated with an increased risk of breast and ovarian cancer among individuals of Ashkenazi Jewish ancestry. My MSKCC colleagues and I also published the first prospective series describing the outcome of preventive ovarian surgery and screening in women at hereditary risk for breast and ovarian cancer. Ongoing research is aimed at defining new genetic risk factors and tailored interventions for families at hereditary risk for cancers of the breast, ovary, colon, prostate, and lymphoid organs.
I have served as a member of the National Cancer Institute’s Cancer Genetics Working Group, chaired the subcommittee on cancer genetics of the American Society of Clinical Oncology, and serve on a number of local and federal advisory committees dealing with cancer genetic testing and genomic risk profiling.
- Clinical Expertise: Genetic Predisposition to Cancer; Lymphomas and Hodgkin's Disease; Cancer Risk Counseling
- Languages Spoken: English
- Education: MD, Harvard Medical School
- Residencies: Lenox Hill Hospital
- Fellowships: Memorial Sloan Kettering Cancer Center
- Board Certifications: Internal Medicine; Medical Oncology
Research is integral to our mission at Memorial Sloan Kettering, and clinical trials help us discover better forms of patient care and treatment. For you, this could mean access to a new therapy or therapy combination. Click to see a list of the trials I’m currently leading.
Clinical Trials Led by Kenneth Offit
Clinical Trials Co-Investigated by Kenneth Offit
- A Genotype-Phenotype Urothelial Cancer Study
- Adherence to Comprehensive, Multi-Organ Screening Recommendations in Hereditary Non-Polyposis Colorectal Cancer (HNPCC) Patients
- Evaluating the Causes of Cancer in Young Patients
- Hereditary Colorectal Cancer Family Registry
- Prospective Ascertainment for Late Effects Among Cancer Survivors
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