Full Title
Randomized Phase II/III Trial of Sentinel Lymph Node Biopsy Versus Elective Neck Dissection for Early-Stage Oral Cavity Cancer (NRG-HN006) (CIRB)Purpose
Researchers in this study want to compare sentinel lymph node biopsy surgery with standard neck dissection as part of the treatment for people with early-stage oral cavity (mouth) cancer. Sentinel lymph node biopsy is a procedure that removes a smaller number of lymph nodes from the neck because it uses an imaging agent to see which lymph nodes are most likely to have cancer. Standard elective neck dissection removes many of the lymph nodes in the neck but may reduce shoulder mobility and strength.
In this study, patients with squamous cell carcinoma of the oral cavity whose PET/CT scans do not show evidence of cancer spread will be randomly assigned to have either sentinel lymph node biopsy or elective neck dissection. Investigators will also compare quality of life and shoulder function between the two groups.
Contact
For more information about this study and to ask about eligibility, please contact the office of Dr. Jennifer Cracchiolo at 646-497-9161.