A Phase III Study Comparing Two Surgery Methods to Treat Cancer in the Lung in Patients with Bone Cancer

Full Title

A Phase 3 Randomized Controlled Trial Comparing Open vs Thoracoscopic Management of Pulmonary Metastases in Patients with Osteosarcoma (AOST2031) (CIRB)

Purpose

The purpose of this study is to compare two different approaches to surgery for children and adults with osteosarcoma (bone cancer) that has spread (metastasized) to the lungs. Participants will be randomly assigned to one of two techniques:

  • Open thoracic surgery, which is performed through a single larger incision between the ribs to open up the chest and remove the cancer from the lungs.
  • Video-assisted thoracoscopic surgery (VATS), where the surgeon makes several small incisions in the chest and uses a small camera to help guide removal of the cancer.

Contact

For more information about this study and to inquire about eligibility, please contact 1-833-MSK-KIDS.

Protocol
22-232
Phase
Phase III (phase 3)
Disease Status
Newly Diagnosed & Relapsed/Refractory
Investigator
ClinicalTrials.gov ID
NCT05235165