A Phase 1/2 Study of BGB-11417 Given Alone and With Carfilzomib and/or Dexamethasone to Treat Multiple Myeloma

Full Title

A Study of BGB-11417 Given Alone and in Combination With Carfilzomib and/or Dexamethasone, Dexamethasone/Daratumumab, and Dexamethasone/Pomalidomide in People With Multiple Myeloma

Purpose

Researchers want to learn if BGB-11417 given alone or with dexamethasone and carfilzomib may help people with multiple myeloma. The people in this study have multiple myeloma that keeps growing after standard treatment. BGB-11417 blocks a protein called Bcl-2 that helps multiple myeloma cells to live and grow.

If you join this study, you will get one of these treatments:

• BGB-11417 alone
• BGB-11417 plus dexamethasone
• BGB-11417 plus dexamethasone and a higher dose of carfilzomib
• BGB-11417 plus dexamethasone and a lower dose of carfilzomib
• Dexamethasone plus a higher dose of carfilzomib

Contact

For more information and to see if you can join this study, please contact the office of Dr. Malin Hultcrantz 646-608-3714.