A Phase 2 Study of Zipalertinib in People With Advanced Non-Small Cell Lung Cancer

Full Title

An Open-Label, Phase 2b, Global Multicenter Cohort Trial to Assess the Safety and Efficacy of Zipalertinib in Patients with Locally Advanced or Metastatic Non-Small Cell Lung Cancer with Exon 20 Insertion and Uncommon/Single or Compound Epidermal Growth Factor Receptor Mutations

Purpose

The purpose of this study is to see how well zipalertinib works to treat advanced lung cancer. The people in this study have non-small cell lung cancer (NSCLC) that has spread. The cancer also has a mutation (change) in the EGFR gene. When people have an EGFR mutation, the EGFR protein on their cells can trigger cancer growth.

Zipalertinib works against the EGFR protein to slow or stop the growth of NSCLC. It is taken orally (by mouth).

Contact

For more information and to see if you can join this study, please call Dr. Helena Yu’s office at 646-608-3912.