Full Title
An Open-Label, Multicenter Phase 2 Study to Evaluate the Efficacy and Safety of BCL2 Inhibitor BGB-11417 in Patients With Relapsed/Refractory Waldenström’s MacroglobulinemiaPurpose
In this study, researchers want to learn if BGB-11417 works well against Waldenström’s macroglobulinemia (WM). The people in this study have WM that keeps growing or came back after treatment.
BGB-11417 blocks a protein called Bcl-2, which helps blood cancer cells to live and grow. It is taken orally (by mouth).
Who Can Join
To join this study, there are a few conditions. You must:
- Have WM that keeps growing or came back even after treatment.
- Have recovered from the serious side effects of prior cancer therapies before taking BGB-11417.
- Be able to walk and do routine activities for more than half the time you are awake.
- Be age 18 or older.
Contact
For more information and to see if you can join this study, please call Dr. Lia Palomba’s office at 646-608-3711.
Protocol
24-067
Phase
Phase II (phase 2)
Disease Status
Relapsed or Refractory
Investigator
Co-Investigators
Diseases
ClinicalTrials.gov ID
NCT05952037