A Phase 2 Study of Ivonescimab in People With Endometrial and Cervical Cancers

Full Title

Purpose

Researchers want to see how well ivonescimab works as a treatment for endometrial and cervical cancers. The people in this study have endometrial or cervical cancer that keeps growing after treatment.

Ivonescimab works by binding to two proteins. One is found on the surface of cancer cells and the other is on immune system cells. Ivonescimab may strengthen your immune system’s ability to fight cancer cells by activating your own cells to destroy your tumor. It is given intravenously (by vein).

Who Can Join

To join this study, there are a few conditions. You must:

• Have endometrial or cervical cancer that keeps growing after at least 1 regimen of treatment that included a platinum-containing drug.
• Have recovered from the serious side effects of prior therapies before getting ivonescimab.
• Be able to walk and do routine activities for more than half the time you are awake.
• Be age 18 or older.

Contact

For more information or to see if you can join this study, please call Dr. Maria Rubinstein at 646-888-6954.