- It is used to treat cancer.
- It is used to treat nephrotic syndrome.
- It may be given to you for other reasons. Talk with the doctor.
- If you have an allergy to cyclophosphamide or any other part of this drug.
- If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
- If you have any of these health problems: Bone marrow disease or urinary tract block.
- Tell dentists, surgeons, and other doctors that you use this drug.
- Avoid driving and doing other tasks or actions that call for you to be alert or have clear eyesight until you see how this drug affects you.
- Very bad and sometimes deadly allergic side effects have rarely happened. Talk with your doctor.
- Have blood work checked as you have been told by the doctor. Talk with the doctor.
- Talk with your doctor before getting any vaccines. Use with this drug may either raise the chance of an infection or make the vaccine not work as well.
- You may bleed more easily. Be careful and avoid injury. Use a soft toothbrush and an electric razor.
- Very bad and sometimes deadly infections have happened in patients who take this drug. If you have any infection, are taking antibiotics now or in the recent past, or have had many infections, talk with your doctor.
- You may have more chance of getting an infection. Wash hands often. Stay away from people with infections, colds, or flu.
- Very bad and sometimes deadly heart problems like heart failure have happened with this drug. Talk with the doctor.
- Other types of cancer may rarely happen later in life.
- Pass urine often. You need to empty your bladder often. Drinking lots of liquids will help.
- If you have upset stomach, throwing up, loose stools (diarrhea), or are not hungry, talk with your doctor. There may be ways to lower these side effects.
- If you are 65 or older, use this drug with care. You could have more side effects.
- This drug may affect being able to father a child. In some people, this may go back to normal but may take some time. Talk with the doctor.
- If you are a man and have sex with a female who could get pregnant, protect her from pregnancy during care and for at least 4 months after stopping this drug. Use birth control that you can trust.
- If you are a man and your sex partner gets pregnant while you take this drug or within 4 months after your last dose, call your doctor right away.
- This drug may cause you to not be able to get pregnant. Talk with the doctor.
- This drug may cause harm to the unborn baby if you take it while you are pregnant.
- Use birth control that you can trust to prevent pregnancy while taking this drug and for up to 12 months after this drug.
- If you get pregnant while taking this drug or within 12 months after your last dose, call your doctor right away.
- Tell your doctor if you are breast-feeding. You will need to talk about any risks to your baby.
- Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
- Signs of infection like fever, chills, very bad sore throat, ear or sinus pain, cough, more sputum or change in color of sputum, pain with passing urine, mouth sores, or wound that will not heal.
- Signs of bleeding like throwing up blood or throw up that looks like coffee grounds; coughing up blood; blood in the urine; black, red, or tarry stools; bleeding from the gums; vaginal bleeding that is not normal; bruises without a reason or that get bigger; or any bleeding that is very bad or that you cannot stop.
- Signs of low sodium levels like headache, trouble focusing, memory problems, change in thinking clearly and with logic, weakness, seizures, or change in balance.
- Feeling very tired or weak.
- Shortness of breath, a big weight gain, swelling in the arms or legs.
- Very bad dizziness or passing out.
- A heartbeat that does not feel normal.
- A wound that does not heal.
- Not able to pass urine or change in how much urine is passed.
- Very bad and sometimes deadly urinary tract problems like hemorrhagic cystitis have happened with this drug. Call your doctor right away if you have blood in the urine or pain when passing urine.
- Very bad and sometimes deadly liver problems have happened with this drug. Call your doctor right away if you have signs of liver problems like dark urine, feeling tired, not hungry, upset stomach or stomach pain, light-colored stools, throwing up, or yellow skin or eyes.
- Not hungry.
- Loose stools (diarrhea).
- Hair loss.
- Upset stomach or throwing up.
- Belly pain.
- Change in color of skin.
- Change in nails.
- Drink lots of noncaffeine liquids unless told to drink less liquid by your doctor.
All oral products:
- Take with or without food.
- Wear gloves when touching this drug.
- Swallow whole. Do not chew, break, or crush.
- Do not open the capsules.
- If the capsule is opened or broken, do not touch the contents. If the contents are touched or they get in the eyes, wash hands or eyes right away.
- If the tablet is crushed or broken, do not touch the contents. If you do touch the contents or get it in your eyes, wash hands or eyes right away.
- It is given as an infusion into a vein over a period of time.
All oral products:
- Take a missed dose as soon as you think about it.
- If it is close to the time for your next dose, skip the missed dose and go back to your normal time.
- Do not take 2 doses at the same time or extra doses.
- Call the doctor to find out what to do.
All oral products:
- Store at room temperature.
- Store in a dry place. Do not store in a bathroom.
- This drug will be given to you in a hospital or doctor’s office. You will not store it at home.
- Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
- Check with your pharmacist about how to throw out unused drugs.
- If your symptoms or health problems do not get better or if they become worse, call your doctor.
- Do not share your drugs with others and do not take anyone else’s drugs.
- Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
- Talk with the doctor before starting any new drug, including prescription or OTC, natural products, or vitamins.
- Some drugs may have another patient information leaflet. If you have any questions about this drug, please talk with your doctor, nurse, pharmacist, or other health care provider.
- If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
If you have any questions or concerns, talk with a member of your healthcare team. You can reach them Monday through Friday from 9:00 am to 5:00 pm at ____________________. After 5:00 pm, during the weekend, and on holidays, please call____________________. If there’s no number listed, or you’re not sure, call 212-639-2000.
Cyclophosphamide©2016 Memorial Sloan Kettering Cancer Center - Generated on April 30, 2016