Eating and Drinking Before Your Surgery or Procedure When Taking GLP-1 Medicines

Time to Read: About 1 minute

GLP-1 medicines are medicines that are prescribed for weight loss. These medicines are also used in the treatment of diabetes and heart disease. If you take a GLP-1 medicine, ask the healthcare provider doing your procedure what to do before your procedure. You may need to stop taking it, follow different eating and drinking instructions before your procedure, or both. Follow your healthcare provider’s instructions.

Examples of medicines that are GLP-1 medicines are listed below. There are others, so make sure your care team knows all the medicines you take. 

  • Semaglutide (Wegovy®, Ozempic®, Rybelsus®)
  • Exenatide (Byetta, Bydureon®)
  • Tirzepatide (Zepbound®, Mounjaro®)
  • Dulaglutide (Trulicity®)
  • Liraglutide (Saxenda®)
  • Insulin Glargine and Lixisenatide (Soliqua®)
  • Insulin Degludec and Liraglutide (Xultophy®)

Instructions for eating and drinking before your surgery of procedure

These instructions are to keep you safe. It is dangerous to have food or liquid in your stomach when you get sedation or anesthesia. Following these instructions will help make sure your stomach is empty.

It is very important to follow these instructions. If you do not follow them, your surgery or procedure may be delayed or canceled.

The day before your surgery or procedure

The day before your surgery or procedure, follow a clear liquid diet. A clear liquid diet includes only liquids you can see through. Keep following it until midnight (12 a.m.).

Visit www.msk.org/pe/clear_liquid_diet to learn more.

If you have diabetes, pay attention to the amount of sugar in your drinks. It will be easier to control your blood sugar levels if you include sugar-free, low-sugar, or no added sugar versions of these drinks.

‌ 
After midnight (12 a.m.), do not eat or drink anything. You may have sips of water with your medicines.

Last Updated

July 31, 2025

Learn about our Health Information Policy.

Tell us what you think

Tell us what you think

Your feedback will help us improve the educational information we provide. Your care team cannot see anything you write on this feedback form. Please do not use it to ask about your care. If you have questions about your care, contact your healthcare provider.

While we read all feedback, we cannot answer any questions. Please do not write your name or any personal information on this feedback form.

Questions Yes Somewhat No
Please do not write your name or any personal information.