This information from Lexicomp® explains what you need to know about this medication, including what it’s used for, how to take it, its side effects, and when to call your healthcare provider.
- It is used to lower the chance of getting an infection in people with bone marrow problems caused by chemo.
- It may be given to you for other reasons. Talk with the doctor.
- If you are allergic to this drug; any part of this drug; or any other drugs, foods, or substances. Tell your doctor about the allergy and what signs you had.
This drug may interact with other drugs or health problems.
Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take this drug with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.
- Tell all of your health care providers that you take this drug. This includes your doctors, nurses, pharmacists, and dentists.
- Do not take this drug within 14 days before or 24 hours after you get chemo.
- Have blood work checked as you have been told by the doctor. Talk with the doctor.
- This drug may affect certain lab tests. Tell all of your health care providers and lab workers that you take this drug.
- Low platelet counts have rarely happened with this drug. This may lead to a higher chance of bleeding. Call your doctor right away if you have any unexplained bruising or bleeding.
- Some people with sickle cell disease have had times where the sickle cell disease has gotten worse when taking this drug. Sometimes, this has been deadly. Talk with the doctor.
- A bone marrow problem called myelodysplastic syndrome (MDS) and a type of leukemia have happened with this drug in people with breast or lung cancer who are getting chemo or radiation. Call your doctor right away if you have a fever, feel very tired, or have unexplained bruising or bleeding.
- Tell your doctor if you are pregnant, plan on getting pregnant, or are breast-feeding. You will need to talk about the benefits and risks to you and the baby.
WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:
- Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
- Signs of kidney problems like unable to pass urine, change in how much urine is passed, blood in the urine, or a big weight gain.
- Signs of lung or breathing problems like shortness of breath or other trouble breathing, cough, or fever.
- Fast breathing.
- Dark urine.
- Sweating a lot.
- A fast heartbeat.
- Swelling of belly.
- Feeling full.
- Swelling in the arms or legs.
- Enlarged and ruptured spleens have happened with this drug. Sometimes, ruptured spleens have been deadly. Call your doctor right away if you have left upper stomach pain or left shoulder pain.
- Swelling of the main blood vessel that comes out of the heart (aorta) has happened with this drug. Call your doctor right away if you feel very tired or weak. Call your doctor if you have fever, stomach pain, or back pain.
- Capillary leak syndrome (CLS) is a very bad health problem that has happened with this drug. Sometimes, CLS can be deadly. Tell your doctor right away if you get signs of CLS like change in how much urine is passed; not able to pass urine; blood in the urine; a fast or abnormal heartbeat; chest pain or pressure; dizziness or passing out; shortness of breath; a big weight gain; swelling; throwing up blood or throw up that looks like coffee grounds; or if you have black, tarry, or bloody stools.
All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:
- Feeling dizzy, tired, or weak.
- Upset stomach.
- Stomach pain or diarrhea.
- Decreased appetite.
- Back, bone, joint, or muscle pain.
- Pain in arms or legs.
- Irritation where this drug is given.
These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.
You may report side effects to your national health agency.
Use this drug as ordered by your doctor. Read all information given to you. Follow all instructions closely.
- It is given as a shot into the fatty part of the skin on the top of the thigh or the belly area.
- This drug may be given into the buttocks or the outer area of the upper arm if given by someone else.
- If you will be giving yourself the shot, your doctor or nurse will teach you how to give the shot.
- Wash your hands before and after use.
- Do not shake.
- If you drop this drug on a hard surface, do not use it.
- Do not use if the solution is cloudy, leaking, or has particles.
- Do not use if solution changes color.
- Do not give into skin within 2 inches (5 cm) of the belly button.
- Do not give into a mole, scar, birthmark, or stretchmarks. Do not give into skin that is red, irritated, burned, tender, bruised, hard, or damaged.
- Move the site where you give the shot with each shot.
- To make the injection feel better, take this drug out of the refrigerator and allow it to sit at room temperature for up to 30 minutes before use. Do not remove it from the sealed tray yet. Do not heat this drug.
- Do not use if this drug has been out of the refrigerator for more than 12 hours. Throw the syringe away.
- Throw away after using. Do not use the device more than 1 time.
- Throw away needles in a needle/sharp disposal box. Do not reuse needles or other items. When the box is full, follow all local rules for getting rid of it. Talk with a doctor or pharmacist if you have any questions.
- Call your doctor to find out what to do.
- Store in a refrigerator. Do not freeze.
- Do not use if it has been frozen.
- Store in the original container to protect from light.
- Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
- Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.
- If your symptoms or health problems do not get better or if they become worse, call your doctor.
- Do not share your drugs with others and do not take anyone else’s drugs.
- Some drugs may have another patient information leaflet. If you have any questions about this drug, please talk with your doctor, nurse, pharmacist, or other health care provider.
- Some drugs may have another patient information leaflet. Check with your pharmacist. If you have any questions about this drug, please talk with your doctor, nurse, pharmacist, or other health care provider.
- If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
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