Marstacimab

Adult Medication
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This information from Lexicomp® explains what you need to know about this medication, including what it’s used for, how to take it, its side effects, and when to call your healthcare provider.

What is this drug used for?

  • It is used to prevent bleeding in people with hemophilia.

What do I need to tell my doctor BEFORE I take this drug?

  • If you are allergic to this drug; any part of this drug; or any other drugs, foods, or substances. Tell your doctor about the allergy and what signs you had.

This drug may interact with other drugs or health problems.

Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take this drug with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.

What are some things I need to know or do while I take this drug?

  • Tell all of your health care providers that you take this drug. This includes your doctors, nurses, pharmacists, and dentists.
  • If you will be having surgery, talk with your doctor. You may need to stop this drug and take another drug to lower the chance of blood clots after surgery.
  • If you have a fever, an infection, or an injury, talk with your doctor. You may need to stop this drug for some time.
  • This drug may cause harm to an unborn baby. A pregnancy test will be done before you start this drug to show that you are NOT pregnant.
  • If you may become pregnant, use birth control while taking this drug and for 2 months after your last dose. If you get pregnant, call your doctor right away.
  • Tell your doctor if you are breast-feeding. You will need to talk about any risks to your baby.

What are some side effects that I need to call my doctor about right away?

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:

  • Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
  • A fast heartbeat.
  • Dizziness or passing out.
  • Blood clots may happen with this drug. Tell your doctor if you have ever had a blood clot. Call your doctor right away if you have signs of a blood clot like chest pain or pressure; coughing up blood; shortness of breath; swelling, warmth, numbness, skin color change, or pain in a leg or arm; or trouble speaking or swallowing.

What are some other side effects of this drug?

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:

  • Pain, redness, swelling, or other reaction where the injection was given.
  • Headache.

These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.

You may report side effects to your national health agency.

You may report side effects to the FDA at 1-800-332-1088. You may also report side effects at https://www.fda.gov/medwatch.

How is this drug best taken?

Use this drug as ordered by your doctor. Read all information given to you. Follow all instructions closely.

All products:

  • It is given as a shot into the fatty part of the skin on the top of the thigh or the belly area.
  • If you will be giving yourself the shot, your doctor or nurse will teach you how to give the shot.
  • Before using this drug, take it out of the refrigerator. Allow to reach room temperature (15 to 30 minutes). Do not heat this drug.
  • This drug is colorless to light yellow. Do not use if the solution turns dark yellow or any other color, is cloudy, leaking, or has flakes or particles.
  • If you see a small air bubble in the device, do not get rid of it.
  • Do not shake.
  • Do not give into skin within 2 inches (5 cm) of the belly button.
  • Do not give into bony areas.
  • Do not give into skin that is irritated, tender, bruised, red, scaly, hard, scarred, or has stretch marks.
  • Move the site where you give the shot with each shot.
  • If your dose is more than 1 injection, give each injection in a different area.
  • If you are also using another drug as a shot under the skin, use this drug in a different area of the body if possible.
  • Throw away after using. Do not use the device more than 1 time.
  • Throw away needles in a needle/sharp disposal box. Do not reuse needles or other items. When the box is full, follow all local rules for getting rid of it. Talk with a doctor or pharmacist if you have any questions.

Prefilled syringes:

  • This drug may be given into the outer area of the upper arm if given by someone else.

Prefilled pen:

  • This drug may be given into the buttocks if given by someone else.

What do I do if I miss a dose?

150 mg maintenance dose:

  • Take a missed dose as soon as you think about it.
  • After taking a missed dose, keep taking on your normal day or start a new weekly schedule based on the day the dose is taken.
  • If it has been more than 13 days since your last dose, call your doctor to find out what to do.

300 mg maintenance dose:

  • Take a missed dose as soon as you think about it.
  • After taking a missed dose, keep taking on your normal day or start a new weekly schedule based on the day the dose is taken.

All products:

  • Do not take 2 doses on the same day.
  • If you are not sure what to do if you miss a dose, call your doctor.

How do I store and/or throw out this drug?

  • Store in a refrigerator. Do not freeze.
  • Do not use if it has been frozen.
  • Store in the original container to protect from light.
  • If needed, this drug may be stored at room temperature for up to 7 days. If stored at room temperature and not used within 7 days, throw this drug away.
  • Do not put this drug back in the refrigerator after it has been stored at room temperature.
  • Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
  • Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.

General drug facts

  • If your symptoms or health problems do not get better or if they become worse, call your doctor.
  • Do not share your drugs with others and do not take anyone else’s drugs.
  • Some drugs may have another patient information leaflet. If you have any questions about this drug, please talk with your doctor, nurse, pharmacist, or other health care provider.
  • Some drugs may have another patient information leaflet. Check with your pharmacist. If you have any questions about this drug, please talk with your doctor, nurse, pharmacist, or other health care provider.
  • If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

Consumer Information Use and Disclaimer

This generalized information is a limited summary of diagnosis, treatment, and/or medication information. It is not meant to be comprehensive and should be used as a tool to help the user understand and/or assess potential diagnostic and treatment options. It does NOT include all information about conditions, treatments, medications, side effects, or risks that may apply to a specific patient. It is not intended to be medical advice or a substitute for the medical advice, diagnosis, or treatment of a health care provider based on the health care provider’s examination and assessment of a patient’s specific and unique circumstances. Patients must speak with a health care provider for complete information about their health, medical questions, and treatment options, including any risks or benefits regarding use of medications. This information does not endorse any treatments or medications as safe, effective, or approved for treating a specific patient. UpToDate, Inc. and its affiliates disclaim any warranty or liability relating to this information or the use thereof. The use of this information is governed by the Terms of Use, available at https://www.wolterskluwer.com/en/know/clinical-effectiveness-terms.

Last Reviewed Date

2024-10-17

Copyright

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Last Updated

Sunday, October 20, 2024