This information from Lexicomp® explains what you need to know about this medication, including what it’s used for, how to take it, its side effects, and when to call your healthcare provider.
Brand Names: US
Tremfya; Tremfya One-Press; Tremfya Pen; Tremfya-CD/UC Induction
Brand Names: Canada
Tremfya; Tremfya One-Press
What is this drug used for?
- It is used to treat plaque psoriasis.
- It is used to treat psoriatic arthritis.
- It may be given to your child for other reasons. Talk with the doctor.
What do I need to tell the doctor BEFORE my child takes this drug?
- If your child is allergic to this drug; any part of this drug; or any other drugs, foods, or substances. Tell the doctor about the allergy and what signs your child had.
- If your child has an infection.
- If your child has TB (tuberculosis).
This is not a list of all drugs or health problems that interact with this drug.
Tell the doctor and pharmacist about all of your child’s drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe to give this drug with all of your child’s other drugs and health problems. Do not start, stop, or change the dose of any drug your child takes without checking with the doctor.
What are some things I need to know or do while my child takes this drug?
- Tell all of your child’s health care providers that your child is taking this drug. This includes your child’s doctors, nurses, pharmacists, and dentists.
- Have blood work checked as you have been told by the doctor. Talk with the doctor.
- Your child may have more chance of getting infections. Have your child wash hands often. Avoid crowds and people with infections, colds, or flu.
- Your child will need a TB (tuberculosis) test before starting this drug.
- Talk with the doctor before your child gets any vaccines. Use of some vaccines with this drug may either raise the chance of very bad infection or make the vaccine not work as well.
- Make sure your child is up to date with all vaccines before treatment with this drug.
If your child is pregnant or breast-feeding a baby:
- Talk with the doctor if your child is pregnant, becomes pregnant, or is breast-feeding a baby. You will need to talk about the benefits and risks to your child and the baby.
- If your child used this drug while pregnant, tell the baby’s doctor.
What are some side effects that I need to call my child’s doctor about right away?
WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your child’s doctor or get medical help right away if your child has any of the following signs or symptoms that may be related to a very bad side effect:
- Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
- Signs of infection like fever, chills, very bad sore throat, ear or sinus pain, cough, more sputum or change in color of sputum, pain with passing urine, mouth sores, or wound that will not heal.
- Signs of tuberculosis (TB) like cough, chest pain, shortness of breath, fever, night sweats, weight loss, or feeling sick or weak.
- Signs of herpes infections like cold sores, shingles, genital sores, severe headache, confusion, change in eyesight, eye redness, or eye pain.
- Signs of liver problems like dark urine, tiredness, decreased appetite, upset stomach or stomach pain, light-colored stools, throwing up, or yellow skin or eyes.
- Red, painful, or itchy skin that is hot to touch.
- Passing urine more often.
- Stomach pain or diarrhea.
- Sweating a lot.
- Muscle pain.
- Dizziness or passing out.
What are some other side effects of this drug?
All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your child’s doctor or get medical help if any of these side effects or any other side effects bother your child or do not go away:
- Signs of a common cold.
- Nose or throat irritation.
- Headache.
- Bruising, itching, pain, redness, swelling, or other reaction where the injection was given.
- Joint pain.
These are not all of the side effects that may occur. If you have questions about side effects, call your child’s doctor. Call your child’s doctor for medical advice about side effects.
You may report side effects to your national health agency.
How is this drug best given?
Give this drug as ordered by your child’s doctor. Read all information given to you. Follow all instructions closely.
All products:
- It is given as a shot into the fatty part of the skin on the top of the thigh or the belly area.
- If using a prefilled syringe, this drug may be given into the outer area of the upper arm.
- If you will be giving your child this drug, the doctor or nurse will teach you how to give this drug.
- Wash your hands before and after use.
- Before using this drug, take it out of the refrigerator and leave it at room temperature for 30 minutes.
- Do not heat or microwave.
- Do not remove the cap until you are ready to use. Do not try to put the cap back on. Use within 5 minutes of removing the cap.
- Do not shake.
- Do not use this drug if it has been dropped or if it is broken.
- Do not give into skin within 2 inches (5 cm) of the belly button.
- Do not give into skin that is irritated, tender, bruised, red, scaly, hard, scarred, or has stretch marks.
- Do not give into skin that is affected by psoriasis.
- Do not rub the site where you give the shot.
- This product may contain small white particles. Do not use if the solution is cloudy, leaking, or has large lumps, flakes, or other particles.
- This drug is colorless to a faint yellow. Do not use if the solution changes color.
- Each prefilled syringe, prefilled pen, or One-Press injector is for one use only.
- Throw away any part left over after the dose is given.
- Throw away needles in a needle/sharp disposal box. Do not reuse needles or other items. When the box is full, follow all local rules for getting rid of it. Talk with a doctor or pharmacist if you have any questions.
One-Press injector:
- Push the handle all the way down while you are injecting this drug. Do not lift the device during the injection. If you do, the injector will lock and your child will not get the full dose.
What do I do if my child misses a dose?
- Give a missed dose as soon as you think about it and go back to your child’s normal time.
- Do not give 2 doses at the same time or extra doses.
- If you are not sure what to do if your child misses a dose, call the doctor.
How do I store and/or throw out this drug?
- Store in a refrigerator. Do not freeze.
- Store in the original container to protect from light.
- Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
- Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.
General drug facts
- If your child’s symptoms or health problems do not get better or if they become worse, call your child’s doctor.
- Do not share your child’s drug with others and do not give anyone else’s drug to your child.
- Some drugs may have another patient information leaflet. If you have any questions about this drug, please talk with your child’s doctor, nurse, pharmacist, or other health care provider.
- If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
Consumer Information Use and Disclaimer
This generalized information is a limited summary of diagnosis, treatment, and/or medication information. It is not meant to be comprehensive and should be used as a tool to help the user understand and/or assess potential diagnostic and treatment options. It does NOT include all information about conditions, treatments, medications, side effects, or risks that may apply to a specific patient. It is not intended to be medical advice or a substitute for the medical advice, diagnosis, or treatment of a health care provider based on the health care provider’s examination and assessment of a patient’s specific and unique circumstances. Patients must speak with a health care provider for complete information about their health, medical questions, and treatment options, including any risks or benefits regarding use of medications. This information does not endorse any treatments or medications as safe, effective, or approved for treating a specific patient. UpToDate, Inc. and its affiliates disclaim any warranty or liability relating to this information or the use thereof. The use of this information is governed by the Terms of Use, available at https://www.wolterskluwer.com/en/know/clinical-effectiveness-terms.
Last Reviewed Date
2025-10-15
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